Recent Advances in the Synthesis, Functionalization and Applications of Pyrazole-Type Compounds II

Cover
Half Title
Recent Advances in the Synthesis, Functionalization and Applications of Pyrazole-Type Compounds II
Copyright
Contents
About the Editors
Special Issue “Recent Advances in the Synthesis, Functionalization and Applications of Pyrazole-Type Compounds II”
Convenient Synthesis of N-Heterocycle-Fused Tetrahydro-1,4-diazepinones
Fluorinated and Non-Fluorinated 1,4-Diarylpyrazoles via MnO2-Mediated Mechanochemical Deacylative Oxidation of 5-Acylpyrazolines
On the Question of the Formation of Nitro-Functionalized 2,4-Pyrazole Analogs on the Basis of Nitrylimine Molecular Systems and 3,3,3-Trichloro-1-Nitroprop-1-Ene
Regioselective Synthesis, Structural Characterization, and Antiproliferative Activity of Novel Tetra-Substituted Phenylaminopyrazole Derivatives
Reaction Products of β-Aminopropioamidoximes Nitrobenzenesulfochlorination: Linear and Rearranged to Spiropyrazolinium Salts with Antidiabetic Activity
An Orthogonal Synthetic Approach to Nonsymmetrical Bisazolyl 2,4,6-Trisubstituted Pyridines
Structural Requirements of 1-(2-Pyridinyl)-5-pyrazolones for Disproportionation of Boronic Acids
Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2H-pyrazolo[4,3-c]pyridines
Convenient Synthesis of Pyrazolo[4´,3´:5,6]pyrano[4,3-c][1,2] oxazoles via Intramolecular Nitrile Oxide Cycloaddition
Synthesis, Characterization, and Biological Evaluation of Some Novel Pyrazolo[5,1-b]thiazole Derivatives as Potential Antimicrobial and Anticancer Agents
Recent Developments in Reactions and Catalysis of Protic Pyrazole Complexes
Recent Applications of the Multicomponent Synthesis for Bioactive Pyrazole Derivatives
Revisiting the Chemistry of Vinylpyrazoles: Properties, Synthesis, and Reactivity
1H-Pyrazolo[3,4-b]quinolines: Synthesis and Properties over 100 Years of Research
1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications
	1. Introduction
	2. Structural Features of 1H-Pyrazolo[3,4-b]pyridines: Substitution Patterns
		2.1. Substitution Pattern at N1
		2.2. Substitution Pattern at C3
		2.3. Substitution Pattern at C4, C5, and C6
	3. Synthetic Approaches to 1H-Pyrazolo[3,4-b]pyridines
		3.1. Pyridine Formation onto a Preexisting Pyrazole Ring
			3.1.1. 1,3-Dicarbonyl Compounds and Derivatives as 1,3-CCC-Biselectrophiles
			3.1.2. Michael Acceptors Used as 1,3-CCC-Biselectrophiles
			3.1.3. Diethyl 2-(Ethoxymethylene)malonate as 1,3-CCC-Biselectrophile (Gould–Jacobs Reaction)
			3.1.4. In Situ Formation of the 1,3-CCC-Biselectrophiles or the 1,3-NCC-Dinucleophiles
		3.2. Pyrazole Formation onto a Preexisting Pyridine Ring
		3.3 Other Reactions
	4. Biomedical Applications of 1H-Pyrazolo[3,4-b]pyridines
		4.1 Antitumor Agents
		4.2 Anti-Inflammatory Agents
	5. Conclusions
	References
Title back
Cover back