Recent Advances in Parkinson’S Disease: Translational and Clinical Research

Content: 
Volume Editors
Page iii

Copyright
Page iv

List of Contributors
Pages v-vi

Preface
Pages vii-viii
Anders Björklund, M. Angela Cenci

Chapter 1 - What have we learned from Drosophila models of Parkinson’s disease?
Pages 2-16
Ming Guo

Chapter 2 - Neurotoxic in vivo models of Parkinson’s disease: recent advances
Pages 17-33
Jason R. Cannon, J. Timothy Greenamyre

Chapter 3 - Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson’s disease
Pages 35-51
Stephen B. Dunnett, Mariah Lelos

Chapter 4 - Genetic mouse models of Parkinson’s disease: The state of the art
Pages 53-87
Iddo Magen, Marie-Françoise Chesselet

Chapter 5 - Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson’s disease
Pages 89-111
Ayse Ulusoy, Mickael Decressac, Deniz Kirik, Anders Björklund

Chapter 6 - Modeling neuroinflammatory pathogenesis of Parkinson’s disease
Pages 113-132
Christopher J. Barnum, Malú G. Tansey

Chapter 7 - The MPTP-lesioned non-human primate models of Parkinson’s disease. Past, present, and future
Pages 133-157
Susan H. Fox, Jonathan M. Brotchie

Chapter 8 - Abnormal metabolic brain networks in Parkinson’s disease: from blackboard to bedside
Pages 160-176
Chris C. Tang, David Eidelberg

Chapter 9 - Imaging the nigrostriatal system to monitor disease progression and treatment-induced complications
Pages 177-192
Renju Kuriakose, A. Jon Stoessl

Chapter 10 - Brain imaging after neural transplantation
Pages 193-203
Marios Politis, Paola Piccini

Chapter 11 - Imaging non-motor aspects of Parkinson’s disease
Pages 205-218
David J. Brooks, Nicola Pavese

Chapter 12 - Gene therapy for dopamine replacement
Pages 220-235
Tomas Björklund, Erik Ahlm Cederfjäll, Deniz Kirik

Chapter 13 - Neurotrophic factor therapy for Parkinson’s disease
Pages 237-264
Suresh Babu Rangasamy, Katherine Soderstrom, Roy A.E. Bakay, Jeffrey H. Kordower

Chapter 14 - Neural grafting in Parkinson’s disease: Problems and possibilities
Pages 265-294
Patrik Brundin, Roger A. Barker, Malin Parmar

CHAPTER 15 - Neural grafting in Parkinson’s disease: unraveling the mechanisms underlying graft-induced dyskinesia
Pages 295-309
Emma L. Lane, Anders Björklund, Stephen B. Dunnett, Christian Winkler

Chapter 16 - Deep brain stimulation: state of the art and novel stimulation targets
Pages 311-324
Francisco A. Ponce, Andres M. Lozano

Chapter 17 - The challenge of non-motor symptoms in Parkinson’s disease
Pages 325-341
K. Ray Chaudhuri, Per Odin

Subject Index
Pages 343-358