ras Oncogenes

Front Matter....Pages i-x
Structure and Organization of the ras Gene Family, in Human....Pages 1-10
Transcriptional Regulatory Sequences in the H-ras1 Gene....Pages 11-14
Mutational Activation of Human ras Genes....Pages 15-18
Early Detection of ras Oncogenes Activated by Chemical Carcinogentreatment....Pages 19-22
Ras Mutations in Primary Myelodysplasia and in Patients Following Cytotoxic Therapy....Pages 23-28
High Frequency of ras Oncogene Activation in Benign and Malignant Human Thyroid Tumours....Pages 29-36
Alterations of C-Ha-ras Gene are Associated with c -myc Activation in Human Cervical Cancers....Pages 37-46
Human Thyroid Neoplasms Express ras p21 Protein at High Levels....Pages 47-49
Detection of Mutations in the H-ras Proto-Oncogene in Liver Tumours of the CF1 Mouse....Pages 51-53
Analysis of Hras1-Associated Polymorphisms and Segregation of Taq1-Defined Alleles in Different Human Tumors....Pages 55-65
DNA Methylation of the Human Hras1 Gene....Pages 67-73
Structure of the Drosophila ras2 Bidirectional Promoter....Pages 75-81
The rap Proteins : GTP Binding Proteins Related to p21 ras with a Possible Reversion Effect on ras Transformed Cells....Pages 83-91
Suppression of Temperature-Sensitive RAS in S.cerevisiae by a Putative Protein Kinase....Pages 93-97
The Function of the Mammalian ras Proteins....Pages 99-104
 Ras Proteins as Potential Activators of Protein Kinase C Function....Pages 105-118
Novel Phosphorylation of ras p21 and Mutational Studies....Pages 119-128
The Role of p21 ras in Proliferative Signal Transduction....Pages 129-139
Characterization of ras Proteins Produced at High Levels in the Baculovirus Expression System....Pages 141-144
Phenotypic and Cytogenetic Alterations in Human Skin Keratinocytes after Transfection with the Cellular Harvey-ras (c-Ha-ras) Oncogene....Pages 145-148
Regulation of Cell Death by ras and myc Oncogenes....Pages 149-155
Ras-Induced Phenotypic Changes in Human Fibroblasts....Pages 157-163
Suppression of ras Oncogene Expression Using Sequence Specific Oligodeoxynucleotides....Pages 165-174
Expression of ras, myc and fos Oncogenes During the DMSO-Induced Detransformation of a Colon Carcinoma Line (HT29)....Pages 175-189
The ras Oncogene and Myogenic Commitment and Differentiation....Pages 191-198
Tumorigenic Conversion of in vivo Differentiation Competent Mammary Cells by Introduction and Expression of ras or mil(raf) but not myc ....Pages 199-210
Activation of the Human c-Ha-ras-1 Gene by Chemical Carcinogens in vitro ....Pages 211-215
Activation of ras Oncogenes During Colonic Carcinogenesis: Detection by the Polymerase Chain Reaction....Pages 217-223
Post-Translational Modification of ras Proteins: Palmitoylation and Phosphorylation of Yeast ras Proteins....Pages 225-233
Molecular Interactions of p21....Pages 235-241
Ras-Transformed Cells Contain Microtubules Rich in Modified α-Tubulin in Their Trailing Edges....Pages 243-253
Glutathione S-Transferase/ras Fusion Protein: A Tool for Affinity Chromatography of ras Associated Proteins....Pages 255-260
Aristolochic Acid I Induced Tumors in Wistar Rats Contain Activating Mutations in Codon 61 of the H- ras Protooncogene....Pages 261-262
β-Adrenoceptor is Required for Activation of Avian Erythrocyte G S by Guanine Nucleotides....Pages 263-268
Expression of ras Oncogene in Xenopus laevis ....Pages 269-274
An Appraisal of Four Monoclonal Antibodies Used in the Immunohistochemical Detection of ras p21....Pages 275-280
Identification of a Protein Interacting with ras -p21- by Chemical Cross-Linking....Pages 281-285
Isolation and Partial Characterization of a New Gene ( br1 ) Belonging to the Superfamily of the Small GTP-Binding Proteins....Pages 287-296
Structural Investigations on the G-Binding Domain of p21....Pages 297-301
Molecular Biology of GAP and its Interaction with Oncogenic ras p21....Pages 303-309
The Cooperation between Viral ras Genes and Different Immortalizing Genes Induces the Transformation of Rat Thyroid Epithelial Cells....Pages 311-318
Back Matter....Pages 319-323