Radiation Health Risk Sciences: Proceedings of the First International Symposium of the Nagasaki University Global COE Program “Global Strategic Center for Radiation Health Risk Control”

Front Matter....Pages I-XXXV
Front Matter....Pages 1-1
Global Strategic Center for Radiation Health Risk Control....Pages 3-10
Front Matter....Pages 11-11
Discussion on Points of Radiation Safety and the Scope of The University of Tokyo Global COE Program....Pages 13-22
Network System for Radiation Emergency Medicine in Japan and the Role of Hiroshima University....Pages 23-28
Non-DNA-Targeted Effects and Low-Dose Radiation Risk....Pages 29-33
Update from the Chernobyl Tissue Bank: Effect of Latency on Different Types of Thyroid Cancer Post-Chernobyl....Pages 34-42
Current Risk Estimate of Radiation-Related Cancer and Our Insight into the Future....Pages 43-48
Front Matter....Pages 49-49
Introduction of Atomic Bomb Disease Medical Research in Global COE Program....Pages 51-56
The Offspring of Atomic Bomb Survivors: Cancer and Non-Cancer Mortality and Cancer Incidence....Pages 57-62
Ischemic Heart Disease Among Atomic Bomb Survivors: Possible Mechanism(s) Linking Ischemic Heart Disease and Radiation Exposure....Pages 63-68
Leukemia, Lymphoma, and Multiple Myeloma Incidence in the LSS Cohort: 1950–2001....Pages 69-73
Follow-Up Study of 78 Healthy Exposed Atomic Bomb Survivors for 35 Years in Hiroshima, with Special Reference to Multiple Cancers....Pages 74-78
Front Matter....Pages 79-79
Research Activities and Projects Within a Framework of International Radiation Health Sciences Research....Pages 81-89
Age and Prognosis: Do Adjuvant Therapies Influence the Real Prognosis?....Pages 90-94
Mortality of the Chernobyl Emergency Workers: Analysis of Dose Response by Cohort Studies Covering Follow-Up Period of 1992–2006....Pages 95-102
Twenty Years After Chernobyl: Implications for Radiation Health Risk Control....Pages 103-112
Fallout Exposure of the Population and Thyroid Nodular Diseases....Pages 113-119
Front Matter....Pages 121-121
Higher-Order Chromatin Structure and Nontargeted Effects....Pages 123-126
p53 Dependency of Delayed and Untargeted Recombination in Mouse Embryos Fertilized by Irradiated Sperm....Pages 127-134
The Yin and Yang of Low-Dose Radiobiology....Pages 135-142
Induction and Persistence of Cytogenetic Damage in Mouse Splenocytes Following Whole-Body X-Irradiation Analysed by Fluorescence In Situ Hybridisation. V. Heterogeneity/Chromosome Specificity....Pages 143-149
Front Matter....Pages 151-151
Molecular Understanding of RET/PTC-Mediated Thyroid Carcinogenesis....Pages 153-176
Molecular Prediction of Therapeutic Response and Adverse Effect of Chemotherapy in Breast Cancer....Pages 177-182
Multiple Roles of NBS1 for Genotoxic and Nongenotoxic Stresses....Pages 183-189
Front Matter....Pages 191-191
The DNA Damage Response in Nontargeted Cells....Pages 193-198
The Role of Telomere Dysfunction in Driving Genomic Instability....Pages 199-203
Secretory Clusterin Is a Marker of Tumor Progression Regulated by IGF-1 and Wnt Signaling Pathways....Pages 204-211
Target of Radiation Carcinogenesis Is Protein: Becoming Triploid Is Proximate Cause of Cell Transformation....Pages 212-215
Adult Stem Cells, the Barker Hypothesis, Epigenetic Events, and Low-Level Radiation Effects....Pages 216-226
Combined Effect of Ionizing Radiation and N -Ethyl- N -Nitrosourea on Mutation Induction and Lymphoma Development....Pages 227-231
γ-Ray-Induced Mouse Thymic Lymphomas: Bcl11b Inactivation and Prelymphoma Cells....Pages 232-239
Front Matter....Pages 241-241
Framework of Radiation Safety Management in Japan: Laws, Administrative Agencies, and Supporting Associations....Pages 243-247
Background Radiation Dose to the Population Around the Kudankulam Nuclear Power Plant....Pages 248-253
International Cooperation in Radiation Emergency Medical Preparedness: Establishment of a Medical Network in Asia....Pages 254-259
Front Matter....Pages 261-261
Long-Term Biopsychosocial Consequences of Disaster: Focus on Atomic Bomb Survivors....Pages 263-270
Health Status of Children Exposed to the Chernobyl Accident In Utero: Observations in 1989–2003 and the Implications for Prioritizing Prophylactic Programs....Pages 271-276
Psychological Consequences More Than Half a Century After the Nagasaki Atomic Bombing....Pages 277-282
Front Matter....Pages 283-283
Significance of Oncogene Amplifications in Breast Cancer in Atomic Bomb Survivors: Associations with Radiation Exposure and Histological Grade....Pages 285-293
Paracrine Interactions Between Normal, but Not Cancer, Epithelial and Normal Mesenchymal Cells Attenuate Radiation-Induced DNA Damage....Pages 294-301
Front Matter....Pages 303-303
Thyroid Cancer in Ukraine After the Chernobyl Accident: Incidence, Pathology, Treatment, and Molecular Biology....Pages 305-316
Current Trends in Incidence and Mortality from Thyroid Cancer in Belarus....Pages 317-321
Front Matter....Pages 303-303
The Health Status of the Population in the Semey Region and Scientifically Proven Measures to Improve It....Pages 322-327
Nuclear Explosions and Public Health Development....Pages 328-333
Back Matter....Pages 335-340