Prostaglandin E1 in Atherosclerosis

Front Matter....Pages I-XII
Front Matter....Pages 1-1
Biochemistry and Pharmacology of Prostaglandin E 1 : Introductory Remarks....Pages 3-7
On the Metabolism of Prostaglandin E 1 in Patients Suffering from Arterial Occlusive Disease....Pages 8-12
Effects of Prostaglandins on Platelet Function Ex Vivo and in Animal Thrombosis Models....Pages 13-21
Different Effects of E- and l-Type Prostaglandins on Human Platelet and Polymorphonuclear Cell Function....Pages 22-31
Effects of Prostaglandin E 1 on Low Density Lipoprotein Receptor Activity and Cholesterol Synthesis in Freshly Isolated Human Mononuclear Leukocytes....Pages 32-38
Inhibition of Mitotic and Proliferative Activity of Smooth Muscle Cells by Prostaglandin E 1 ....Pages 39-48
The Effect of Intra-Arterial and Intravenous Prostaglandin E 1 in a Model of Ischaemia in Healthy Volunteers....Pages 49-53
Front Matter....Pages 55-55
Prospective Open Pilot Study to Investigate the Effect of Intermittent Intra-Arterial Infusion Treatment with Prostaglandin E 1 in Patients with Intermittent Claudication....Pages 57-65
Treatment of Stage IIb Peripheral Arterial Occlusive Disease with Short-Term Intra-Arterial Infusion of Prostaglandin E 1 ....Pages 66-74
Clinical Efficacy of Intra-Arterial PGE 1 -Infusion in Intermittent Claudication: A Double-Blind Study....Pages 75-80
Prostaglandin E 1 in Arterial Occlusive Disease in Stages III and IV According to Fontaine....Pages 81-91
Long-Term Intravenous Infusion of PGE 1 in Peripheral Arterial Blood Flow Disorders: Results of an Open Screening Study with Patients in Fontaine’s Stages III and IV....Pages 92-98
Experiences with PGE 1 in Patients with Phlegmasia Coerulea Dolens and in Ergotism....Pages 99-105
PGE 1 in Patients with Macular Degeneration....Pages 106-109
Back Matter....Pages 111-112