Principles and applications of quinoproteins

Cover......Page 1
Half Title......Page 2
Title Page......Page 4
Copyright Page......Page 5
Preface......Page 6
Table of Contents......Page 8
Contributors......Page 12
Part I: Introduction......Page 16
 1. A Brief History of Quinoproteins......Page 18
Part II: Selected Quinoproteins......Page 30
 2. Methanol Dehydrogenase in Gram-Negative Bacteria......Page 32
 3. Bacterial Quinoproteins Glucose Dehydrogenase and Alcohol Dehydrogenase......Page 62
 4. Quinoprotein Aldehyde Dehydrogenases in Microorganisms......Page 80
 5. Methylamine Dehydrogenase......Page 88
 6. Copper-Containing Amine Oxidases......Page 112
 7. Lysyl Oxidase......Page 188
Part III: Biosynthesis, Structure, and Function of Quinoproteins......Page 206
 8. Regulation and Expression of Bacterial Quinoproteins......Page 208
 9. The Role of Quinoproteins in Bacterial Energy Transduction......Page 238
 10. X-Ray Crystallographic Studies of Quinoproteins......Page 260
 11. Resonance Raman Spectroscopy of Quinoproteins......Page 290
Part IV: Analysis and Properties of PQQ and Quinonoid Cofactors......Page 322
 12. The Chemistry of PQQ and Related Compounds......Page 324
 13. Glycine-Dependent Redox Cycling and Other Methods for PQQ and Quinoprotein Detection......Page 346
 14. Biosynthesis of PQQ......Page 358
 15. PQQ, A Growth-Stimulating Substance for Microorganisms......Page 370
Part V: PQQ and Quinoproteins in Medicine and Biotechnology......Page 380
 16. PQQ: Effect on Growth, Reproduction, Immune Function, and Extracellular Matrix Maturation in Mice......Page 382
 17. The Biomedical Significance of PQQ......Page 396
 18. Pharmacological Application of PQQ......Page 410
 19. Quinoproteins as Biocatalysts......Page 424
 20. Quinoproteins as Biosensors......Page 444
Index......Page 462