Prevention of Coronary Heart Disease: From the Cholesterol Hypothesis to w6 w3 Balance (World Review of Nutrition and Dietetics Vol 96)

Contents......Page 6
The Cholesterol Hypothesis – Its Basis and Its Faults......Page 11
Cholesterol Hypothesis, Keys’ Equation and Key Concepts for New Interpretations......Page 12
Current Nutritional Recommendations for the Prevention of Coronary Heart Disease Are Diverse among Scientists’ Groups......Page 13
Effect of Dietary Cholesterol and P/S Ratio of Fatty Acids on Total Cholesterol – Shortand Long-Term Effects Differ......Page 14
Dietary Saturated Fatty Acids, Polyunsaturated Fatty Acids and Cholesterol Are Positively Correlated with Age-Adjusted Relative......Page 18
Increased Coronary Heart Disease Risk by Dietary Recommendations That Were Made Based on the Cholesterol Hypothesis......Page 22
Association of High Total Cholesterol with Coronary Heart Disease Mortality Differs among Subject Populations – Familial Hyperch......Page 29
Characteristics of Familial Hypercholesterolemia......Page 30
Epidemiological Studies Led to Different Conclusions for the Relationship between Total Cholesterol and Coronary Heart D isease......Page 31
Data Rearranged to Convince Japanese People that High Total Cholesterol Is a Major Risk Factor for Coronary Heart Disease......Page 33
The Association of Total Cholesterol with Coronary Heart Disease Differs among Different Age Groups, Which Is Likely to Be Corre......Page 37
Lipid Metabolism Is Likely to Differ Qualitatively between Familial Hypercholesterolemia and Hypercholesterolemic Non-Familial H......Page 41
Cancer and All-Cause Mortalities Are Lower in the Higher Total Cholesterol Groups among General Populations......Page 47
Reports Showing Longer Survival in the Higher Total Cholesterol Groups Except for the Highest Total Cholesterol Group in Western......Page 49
A Large-Scale, Long-Term Follow-Up Study in Austria Demonstrated Age Group Differences in Mortalities......Page 52
Reports on Japanese General Populations Showing Lower Mortalities from Cancer and All Causes in the Higher Total Cholesterol Gro......Page 55
Interpretation of Reports on Korean, British and Japanese American Men......Page 61
Pleiotropic Effects of Statins in the Prevention of Coronary Heart Disease – Potential Side Effects......Page 65
Effectiveness of Statins for the Primary and Secondary Prevention of Coronary Heart Disease Proved in Western Countries......Page 66
Potential Side Effects of Statins......Page 69
Effectiveness of Statin Might Be Different in Japan Where People Eat Relatively Large Amounts of Seafood, and Coronary Heart Dis......Page 72
Side Effects of Statins and Socio-Economic Aspects of Statin Treatment......Page 75
Objective Measures of the Pathology of Coronary Heart Disease......Page 77
Hisayama Study (Japan) in Which the Cause of Death Was Defined by Postmortem Examination......Page 79
Pathobiological Studies of Americans in the PDAY Study......Page 82
Pulse Wave Velocity Correlated Positively with Ischemic Changes in Electrocardiogram but Not with Total Cholesterol Levels......Page 83
Angiograms Estimate Progression of Atherosclerosis That Was Independent of Total Cholesterol Values......Page 85
Heart Rate Variability Measured with 24-Hour Holter Monitoring Relates to Risk for Coronary Heart Disease......Page 86
Intima-Media Thickness Relates to Dietary Fatty Acids and 5-Lipoxygenase Genotype......Page 87
Hypertension – Relationships to Coronary Heart Disease and Stroke......Page 91
3 Fatty Acids Effectively Prevent Coronary Heart Disease and Other Late-Onset Diseases – The Excessive Linoleic Acid Syndrome......Page 93
Three Different Types of Highly Unsaturated Fatty Acid......Page 94
3 Fatty Acids Are Effective for the Primary and Secondary Prevention of Coronary Heart Disease......Page 96
9) Were More Effective than StatinTreatment for the Secondary Prevention of Coronary Heart Disease......Page 112
Why Isn’t the Causal Relationship between Linoleic Acid and Mortalities from Coronary Heart Disease and Stroke Revealed by Clini......Page 115
Linoleic Acid and Stroke – Epidemiological Studies......Page 117
Factors Affecting the Variability of Serum Polyunsaturated Fatty Acid Compositions......Page 121
Factors Other than Triacylglycerol in Vegetable Oils May Be Involved......Page 128
Mechanisms by Which Dietary Fats Affect Coronary Heart Diesease Mortality......Page 129
Two Dietary Imbalances Cause Diet-Induced Dyslipidemias That Associate with Impaired Human Health......Page 130
3 Fatty Acids......Page 133
The Injury-Inflammation-Ischemia Hypothesis of Atherosclerosis......Page 141
-Fatty Acids and Other Unidentified Factors in Oils......Page 142
Cancers Common in the USA Are\rStimulated by 
 6 Fatty Acids and Large\rAmounts of Animal Fats, but Suppressed\rby  3 Fatty Acids and Cholesterol......Page 153
Enhanced Linoleic Acid Cascade as a Major Risk Factor of Cancers Common in Industrialized Countries......Page 154
Failure to Reveal the Causal Relationship between Linoleic Acid Intake and Cancer Mortality......Page 158
New Directions of Lipid Nutrition for the Primary and Secondary Prevention of Coronary Heart Disease and Other Late-Onset Diseas......Page 161
Critical Comments on Adult Treatment Panel III from National Heart, Lung and Blood Institute, NIH, USA......Page 162
Guidelines from the American College of Physicians for Using Cholesterol Test......Page 163
Workshop of the International Society for the Study of Fatty Acids and Lipids (ISSFAL), NIH, Washington, D.C., 1999......Page 164
Lipid Nutrition for the Prevention of Coronary Heart Disease and Other Late-Onset Diseases – New Directions......Page 165
Reference Books......Page 168
References......Page 169
Subject Index......Page 176