Presystemic Drug Elimination

Content: 
Butterworths International Medical Reviews: Clinical Pharmacology and Therapeutics 1, Page ii
Front Matter, Page iii
Copyright, Page iv
Preface, Pages v-vi, Charles F. George, Andrew G. Renwick, David G. Shand
List of Contributors, Pages vii-viii
1 - First-pass metabolism within the lumen of the gastrointestinal tract, Pages 3-28, A.G. Renwick
2 - Metabolism of drugs by the gastrointestinal tract, Pages 29-42, John Caldwell, Mary Varwell Marsh
3 - In vivo studies of gut wall metabolism, Pages 43-65, Kenneth F. Ilett, Donald S. Davies
4 - Presystemic drug metabolism in the liver, Pages 69-77, Charles F. George, David G. Shand
5 - Physiological factors affecting hepatic first-pass metabolism, Pages 78-95, Grant R. Wilkinson
6 - Presystemic hepatic drug elimination in cirrhosis, Pages 96-107, David G. Shand
First-pass metabolism by the lung: introduction, Pages 111-116, P.A. Routledge, C.F. George
The metabolic potential of the lungs, Pages 117-146, Gary E.R. Hook
8 - First-pass metabolism of endogenous and exogenous substrates by lung, Pages 147-172, Y.S. Bakhle
9 - Presystemic drug metabolism of exogenous compounds by the lung, Pages 173-185, P.A. Routledge
10 - Methods for distinguishing between the various sites of first-pass metabolism in man, Pages 189-205, Charles F. George
Index, Pages 207-213