Practical Transfusion Medicine, 2nd edition

Practical Transfusion Medicine......Page 1
Contents......Page 7
List of Contributors......Page 9
Foreword......Page 13
Preface to the second edition......Page 15
Preface to the first edition......Page 17
Part 1: Basic principles of transfusion......Page 19
1 Introduction......Page 21
2 Essential immunology for transfusion medicine......Page 31
3 Human blood group systems......Page 42
4 Human leucocyte antigens......Page 52
5 Platelet and neutrophil antigens......Page 68
Part 2: Clinical transfusion practice......Page 83
6 The effective and safe use of blood components......Page 85
7 Bleeding associated with trauma and surgery......Page 104
8 Prenatal and childhood transfusions......Page 115
9 Haematological disease......Page 137
10 Transfusion strategies in organ transplant patients......Page 150
11 Inherited and acquired coagulation disorders......Page 156
12 Uses of intravenous immunoglobulin......Page 169
Part 3: Complications of transfusion......Page 177
13 Haemolytic transfusion reactions......Page 179
14 Febrile reactions and transfusion-related acute lung injury......Page 189
15 Urticarial and anaphylactic reactions......Page 197
16 Bacterial contamination......Page 202
17 Post-transfusion purpura......Page 209
18 Immunomodulation and graft-versus-host disease......Page 213
19 Transfusion-transmitted infections......Page 226
20 Variant Creutzfeldt–Jakob disease......Page 247
Part 4: Practice in blood centres and hospitals......Page 257
21 Donors and blood collection......Page 259
22 Blood donation testing and the safety of the blood supply......Page 268
23 Production and storage of blood components......Page 277
24 Medicolegal aspects......Page 292
25 Blood transfusion in hospitals......Page 298
26 Autologous transfusion......Page 316
27 Tissue banking......Page 331
28 Cord blood banking......Page 342
29 Therapeutic apheresis......Page 350
Part 5: Developments in transfusion medicine......Page 361
30 Blood substitutes......Page 363
31 Cytokines in transfusion practice......Page 372
32 Haemopoietic stem cell processing and storage......Page 379
33 Haemopoietic stem cell transplantation and immunotherapy......Page 391
34 Gene therapy......Page 412
35 Recombinant antibodies and other proteins......Page 425
36 Blood transfusion in a global context......Page 437
37 The design of interventional trials in transfusion medicine......Page 446
38 Getting the most out of the evidence for transfusion medicine......Page 458
39 The future of transfusion medicine......Page 467
Index......Page 479
Colour plates......Page 323