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دانلود کتاب Pharmacology for nurses
دانلود کتاب فارماکولوژی برای پرستاران
مشخصات کتاب
Pharmacology for nurses
ویرایش: [Second edition.] نویسندگان: Diane Pacitti, Blaine T. Smith (editor) سری: ISBN (شابک) : 9781284141986, 1284141985 ناشر: سال نشر: 2020 تعداد صفحات: [570] زبان: English فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود) حجم فایل: 50 Mb
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توضیحاتی در مورد کتاب فارماکولوژی برای پرستاران
فارماکولوژی برای پرستاران، ویرایش دوم به دانشجویان پرستاری در مقطع کارشناسی مفاهیم اساسی فارماکولوژی را آموزش می دهد.
توضیحاتی درمورد کتاب به خارجی
Pharmacology for Nurses, Second Edition teaches undergraduate nursing students the basic concepts of pharmacology.
فهرست مطالب
Pharmacology for Nurses Half title page Title page Copyright Dedication Contents Pharmacology for Nurses Introduction About the Editor Contributors Reviewers Section I Pharmacology for Nurses: Basic Principles Chapter 1 Introduction to Pharmacology Introduction Nursing and Pharmacology Drug Classifications Drug Names Prescription and Nonprescription Drugs Controlled Substances Sources of Drug Information QSEN Competencies Overview of the Nursing Process Assessment Nursing Diagnosis Planning Intervention Evaluation Cultural Aspects of Drug Therapy Legal–Ethical Aspects of Drug Therapy Medication Errors How Often Do Medication Errors Occur? How Can Medication Errors Be Prevented? Conclusion: Pharmacology in Nursing Practice Chapter Summary References Chapter 2 Introduction to Drug Action: The Interplay of Pharmacodynamics and Pharmacokinetics Introduction What Happens After a Drug Is Administered? Making the Connection: Pharmacology in Clinical Nursing Practice Pharmacokinetics Versus Pharmacodynamics The Relationship Between the Drug and the Body What Is a Drug? Advances in New Drug Development: Personalized Medicine Drug Nomenclature Chemical Name Generic Name Brand Name The Liver: Anatomical First Stop for Orally Administered Drugs Nursing Considerations Drug Meet Patient; Patient Meet Drug Toxicology Nursing Considerations What, Then, Is the Right Dose? The Interplay of Pharmacokinetics and Pharmacodynamics Pharmacodynamics Pharmacokinetics Biopharmaceutics Nursing Considerations Clinical Pharmacology Pharmacodynamics What the Drug Does to the Body The Mechanism of Drug Action The Receptor Molecule The Nature of Ligand-Receptor Interactions: Chemical Bonding Interactions/Forces Nursing Considerations The Drug–Receptor Complex The Drug–Receptor Interaction and Therapeutic Response Types of Receptors Transmembrane Receptor Activation and Response Signal Transduction The Dose-Response Relationship Pharmacodynamic Parameters Obtained from the Dose-Response Curve Efficacy Potency Potency vs. Efficacy: A Source of Confusion Nursing Considerations Limitations of a Dose-Response Curve The Drug Activity Profile Pharmacodynamic Parameters Obtained from the Drug Activity Profile Duration of Action Onset of Action Therapeutic Index Classes of Medications Agonist Drugs Mimic Ligand-Receptor Activation Responses Antagonist Drugs Block the Receptor’s Activation Response Different Types of Antagonists Nursing Considerations Variability in Pharmacodynamics Pharmacokinetics How the Body Affects the Drug Overview of the Pharmacokinetic Processes, ADME Absorption Distribution Metabolism Elimination Nursing Considerations Overview of Pharmacokinetic Terminology The Pharmacokinetic Parameters Used to Characterize the Rate of Drug Movement Nursing Considerations Pharmacokinetic Studies and Determination of Kinetic Parameters The Plasma Level-Time Curve Rate Processes of Pharmacokinetics Zero-Order Rate Process Nursing Considerations The First-Order Rate Process Further Explanation of Rate Constants in Pharmacokinetics Half-Life in Pharmacokinetics Nursing Considerations Drug Absorption: The “A” in ADME The Pharmacokinetics of Oral Absorption Bioavailability Factors Affecting the Rate and Extent of Absorption Impact of First-Pass Effect on Bioavailability Steady-State Drug Levels Nursing Considerations Distribution: The “D” in ADME Pharmacokinetics: Rate of Drug Distribution Pharmacokinetic Models: Compartmental Model Theory One-Compartment Model Multicompartment Model Volume of Distribution Drug Binding to Plasma Proteins Competition for Binding Sites Ramifications of Protein Binding on Therapy Metabolism: The “M” in ADME Enzyme Reactions in the Liver Metabolism and Liver Blood Flow Drug Interactions Involving Drug Metabolism Nursing Considerations Elimination: The “E” in ADME Biliary Excretion of Drugs Drug Clearance Glomerular Filtration Active Renal Secretion Tubular Reabsorption Case Study: Making the Connection to Clinical Nursing Considerations Affecting Drug Delivery: Dosing Frequency, Timing, and Route Chronic Medication Use: Long-Term Dosing Regimens Chapter Summary References External Links Chapter 3 Medication Administration Introduction Before Administering Medications: The Eight Medication “Rights” Procedures for Administering Medications Which Factors Hamper Safe Medication Administration? Systemic Factors in Medication Errors Proper Procedure for Administering All Medications Administering Oral Medications Injecting Medications Safely Giving Subcutaneous Injections Preparing the Medication for a Subcutaneous Injection Injectable Pens Rotating Injection Sites for Subcutaneous Injections General Guidelines for Subcutaneous Injections Intramuscular Injections Anatomic Locations for Administering Intramuscular Injections Supplies Needed for Administering Intramuscular Injections General Procedure for Administering Intramuscular Injections Intravenous and Intraosseous Medications IV Medication Safety Issues Matters of Key Concern When Administering IV Medications Administering an IV Medication Identifying a Site Inhaled Medications Proper Procedure for Using a Metered-Dose Inhaler or Dry-Powder Inhaler Delivering Medication with an Inhaler Proper Procedure for Administering a Nasal Spray Using a Nebulizer Preparing for Nebulizer Therapy Using the Nebulizer Medication Transfer Across Permeable Tissues Administering a Transdermal Patch Applying Topical Preparations Vaginal Rings Administering Vaginal Rings Administering Rectal Suppositories Buccal and Sublingual Administration Administering a Sublingual or Buccal Medication Medication Errors What are Medication Administration Errors? Causes and Prevention of Medication Errors Conclusion: Medication Administration in Nursing Practice Chapter Summary Suggested Readings References Section II The Pharmacology of Physiological Systems Chapter 4 Central Nervous System Drugs Nervous System Physiology Conditions Affecting CNS Function Drugs Used for Conditions of the Central Nervous System Classes of Medications for Treating CNS Disorders Analgesics and Pain Management Acute Versus Chronic Pain Narcotics Nursing Process Nonsteroidal Anti-Inflammatory Drugs Nursing Process Seizure Disorders and Epilepsy Anticonvulsants Valproic Acid Phenobarbital Levetiracetam Phenytoin Benzodiazepines Anticonvulsant Side Effects Nursing Process Neurodegenerative Diseases Parkinson’s Disease Carbidopa–Levodopa Nursing Process for Carbidopa–Levodopa Ropinirole Nursing Process for Ropinirole Benztropine Nursing Process for Benztropine Amantadine Nursing Process for Amantadine Alzheimer Disease Nursing Process Amyotrophic Lateral Sclerosis Nursing Process Musculoskeletal Dysfunction Muscle Relaxants Specific Drugs and Their Uses Side Effects and Contraindications Nursing Process Local Anesthetics Specific Drugs and Uses Nursing Process Chapter Summary Suggested Readings References Chapter 5 Autonomic Nervous System Drugs Introduction The Three Systems of the ANS Anatomy of the Autonomic Nervous System Integration of ANS Systems Sympathetic Nervous System Parasympathetic Nervous System Neurotransmitters in the Autonomic Nervous System Adrenergic Receptors Drugs That Affect the ANS Adrenergic Agonist Drugs Nonselective Agents Selective Adrenergic Agents Nursing Considerations for Adrenergic Drugs Adrenergic Antagonists Alpha-Adrenergic Antagonists Selectivity Nursing Considerations for α-Receptor Antagonists Beta-Adrenergic Antagonists Selectivity Nursing Considerations for ß-Adrenergic Antagonists Cholinergic Drugs Cholinergic Agents Directly Acting Acetylcholine Receptor Agonist Acetylcholinesterase Inhibitors Nursing Considerations for Cholinergic Agonists Nursing Interventions Cholinergic Antagonists Clinical Indications for Use Individual Cholinergic Antagonists Nursing Process for Cholinergic Antagonists Nursing Interventions Chapter Summary Suggested Readings References Chapter 6 Cardiovascular Medications Introduction The Cardiovascular System Treatment of High Blood Pressure What Is High Blood Pressure? JNC 7: “Older” Guidelines for Treatment of Hypertension JNC 8: Updated Guidelines for Treatment of Hypertension The Renin–Angiotensin–Aldosterone System (RAAS) Direct Renin Inhibitors Angiotensin-Converting-Enzyme Inhibitors (ACE Inhibitors) Angiotensin II Receptor Blockers (ARBs) Aldosterone Antagonists (AAs) The Role of the Autonomic Nervous System in Blood Pressure Regulation Adverse Effects of Beta-Blockers Blockade of α1-Receptors Adverse Effects of Alpha-Blockers Drug–Drug Interactions Calcium-Channel Blockers Adverse Effects of Calcium Channel Blockers Diuretics Thiazide Diuretics Loop Diuretics Potassium-Sparing Diuretics Hypertensive Emergencies Cardiac Agents Coronary Artery Disease Chest Pain/Angina Exertional Angina Variant Angina Unstable Angina Antianginal Agents Nursing Considerations Hyperlipidemia Statin Drugs Fibrates Niacin Bile Acid Sequestrants Congestive Heart Failure Inotropic Agents Cardiac Glycosides Nursing Considerations Prevention of Thrombosis and Stroke: Anticoagulant Therapy Anticoagulants Heparin Low-Molecular-Weight Heparin Oral Anticoagulants Warfarin Direct Thrombin Inhibitors Direct Factor Xa Inhibitors Antiplatelet Agents Antiarrhythmic Agents Group I Antiarrhythmics: Sodium-Channel Blockers Group II Antiarrhythmics: Beta-Blockers Group III Antiarrhythmics: Potassium-Channel Blockers Group IV Antiarrhythmics: Calcium-Channel Blockers Group V Antiarrhythmics: Miscellaneous Chapter Summary References Chapter 7 Respiratory Medications Introduction Assessment of Lung Function Asthma Approach to the Treatment of Asthma Oral Preventive Medications Leukotriene-Receptor Antagonists Thromboxane Antagonists Oral Corticosteroids Inhaled Preventive Medications Inhaled Corticosteroids Inhaled Long-Acting Beta Agonists Combination Inhalers (Corticosteroid + LABA) Injected Preventive Therapies Monoclonal Antibodies Methylxanthines Fast-Acting “Rescue” Medications Short-Acting Inhaled Beta Agonists Anticholinergic Agents Intravenous Corticosteroids Epinephrine Late-Phase Asthma Treatment: Emergency Room Only Chronic Obstructive Pulmonary Disease COPD Adjunct Therapies Antibiotics Smoking Cessation Mucus Reduction Smoking-Cessation Therapy Oral Medications for Smoking Cessation Antidepressants Nicotinic-Receptor Agonists Nicotine Replacement Therapies Chapter Summary Suggested Readings References Chapter 8 Pharmacology of the Gastrointestinal Tract Introduction The Nursing Care Process Drugs to Control Gastric Acidity Antacids Drug–Drug Interactions Histamine 2 (H2) Receptor Antagonists Drug–Drug Interactions Proton-Pump Inhibitors Drug–Drug Interactions Mucosal Protectants Drug–Drug Interactions Drugs to Stimulate Gastrointestinal Motility Cholinergic Mimetic Agents Dopamine (D2) Receptor Blockers Drug–Drug Interactions Drugs to Control Diarrhea Opioid Agonists Drug–Drug Interactions Bismuth Compounds Octreotide Drugs to Relieve Constipation Bulk-Forming Laxatives Drug–Drug Interactions Stimulant Laxatives Drug–Drug Interactions Stool Softeners/Surfactants Drug–Drug Interactions Osmotic Laxatives Drug–Drug Interactions Drugs to Treat Irritable Bowel Syndrome Anticholinergics Serotonin 5-HT Receptor Agonists and Antagonists Drug–Drug Interactions Chloride-Channel Activators Drug–Drug Interactions Drugs to Control Nausea and Vomiting 5-HT3 Receptor Antagonists Drug–Drug Interactions Corticosteroids Neurokinin-1 (NK1) Receptor Antagonists Drug–Drug Interactions Dopamine-Receptor Antagonists Drug–Drug Interactions Antihistamines and Anticholinergics Cannabinoids Drug–Drug Interactions Drugs to Treat Inflammatory Bowel Disease Aminosalicylates Drug–Drug Interactions Glucocorticoids Purine Analogs Drug–Drug Interactions Methotrexate Anti-Tumor Necrosis Factor Therapy Anti-Integrin Therapy Drug–Drug Interactions Bile Acid Therapy for Gallstones Drug–Drug Interactions Chapter Summary References Chapter 9 Endocrine System Drugs Introduction Endocrine Glands and Their Hormones Hypothalamus Pituitary Pineal Gland Thyroid Parathyroid Thymus Pancreas Adrenal Glands Reproductive Glands Treating Endocrine Conditions Diabetes Mellitus Insulin Nursing Process Oral and Injectable Hypoglycemic Medications Nursing Process Thyroid Disorders Thyroid Hormone Replacement Nursing Process Thyroid Hormone Suppression Nursing Process Polycystic Ovary Syndrome (PCOS) Nursing Process Adrenal Disorders Adrenal Insufficiency Nursing Process Hypercortisolism (Cushing Disease) Nursing Process Hyperaldosteronism (Conn Disease) References Chapter 10 Medications for Eye and Ear Disorders Introduction Medications for Ophthalmic Disorders Proper Instillation of Topical Ophthalmic Medication Drops Ointments Glaucoma Beta Blockers Therapeutic and Adverse Effects Drug Interactions Miotics Carbonic Anhydrase Inhibitors Therapeutic and Adverse Effects Drug Interactions Alpha-Adrenergic Agonists Therapeutic and Adverse Effects Drug Interactions Prostaglandin Analogs Therapeutic and Adverse Effects Adverse Drug Reactions Chronic Dry or Bloodshot Eyes Ocular Lubricants Therapeutic and Adverse Effects Drug Interactions Ophthalmic Vasoconstrictors Therapeutic and Adverse Effects Drug Interactions Corticosteroids Therapeutic and Adverse Effects Drug Interactions Ophthalmic Antibiotics Therapeutic and Adverse Effects Drug Interactions Drugs Used in Treating Otic Disorders Prevention Begins at Birth Acute Otitis Media Choosing an Antibacterial Agent Treatment for Antibiotic-Resistant AOM Pharmacodynamics Therapeutic and Adverse Effects Drug Interactions Otitis Media with Effusion Otitis Externa and Its Management Prevention Treatment Topical Medications Systemic Treatment Fungal Otitis Externa (Otomycosis) Treatment Analgesics Chapter Summary References Chapter 11 Pharmacology of the Genitourinary System Introduction Urinary Tract Infections Complicated UTI in Adults Complicated UTI in Pediatric Patients Medications for Treatment of Uncomplicated UTI (Cystitis) Trimethoprim-Sulfamethoxazole Nitrofurantoin Fosfomycin Trometamol Second-Line Agents for UTI Beta-Lactam Agents Non-Antimicrobial Biological Mediators for Prevention of Uncomplicated Recurrent Cystitis Cranberry Juice, Capsules, or Tablets Topical/Local Estrogen Vaccines and Probiotic Application Treatment of Complicated UTI Candida albicans Vaginitis (Vaginal Yeast Infection) Benign Hyperplasia of the Prostate Medications for the Treatment of BPH Antimuscarinic Agents (Tolterodine) Selective α1-Adrenoreceptor Antagonists (Alfuzosin, Prazosin, Doxazosin, Tamsulosin, Terazosin) 5-α-Reductase Inhibitors (Finasteride, Dutasteride) PDE-5 Inhibitors (Tadalafil) Erectile Dysfunction Medications for the Treatment of ED PDE-5 Inhibitors (Sildenafil, Tadalafil, Vardenafil) Alprostadil Sexually Transmitted Infections Sexually Transmitted Viral Infections HPV, Genital Warts, and Cervical Cancer Herpes and HIV Infections Sexually Transmitted Bacterial Infections Sexually Transmitted Parasitic Infections Female Hormonal Contraception Estrogen Analogs Progestins Testosterone Pharmacodynamics Delivery System Comparison Oral Hormonal Contraceptives Transdermal Contraceptive System Vaginal Rings Implants Intrauterine Device Emergency Contraception Urinary Incontinence Chapter Summary References Section III Special Conditions and Supplemental Areas Chapter 12 Drugs Associated with Pregnancy, Labor and Delivery, and Lactation Introduction FDA Pregnancy Categories Medication Use on a Preconception Basis and in Early Pregnancy Physiological Changes in Pregnancy Use of Nonprescribed and Illicit Drugs Patient Emotions Around Medication Use Common Conditions Arising in Pregnancy Constipation Diabetes Mellitus Heartburn Nausea and Vomiting in Pregnancy Hypertension in Pregnancy Group B Streptococcal Infection Human Immunodeficiency Virus Neoplastic Disease Drugs Used During Labor Preterm Labor Tocolytic Medications Labor Induction Analgesia/Anesthesia Drugs Used During the Postpartum Period Drugs Administered During Lactation Chapter Summary References Chapter 13 Pharmacology in Dermatologic Conditions Introduction Topical Administration Systemic Administration Intralesional Administration Physiological Factors Affecting Transdermal Medication Administration Acne Medications: An Example of Delivery Systems Pharmacology of Topical Acne Medication Benzoyl Peroxide Salicylic Acid Tretinoin Pharmacology of Systemic Acne Medications Tetracyclines Isotretinoin Hormonal Medications Pharmacology of Intralesional Injection Acne Treatment Intralesional Steroid Injection Atopic Dermatitis Pharmacology of Topical Preparations for AD Triamcinolone Acetonide Emollient Ointment Bacterial Skin Infections Antifungal Preparations Pharmacology of Common Antifungal Medications Ketoconazole 2% Cream Terbinafine Chapter Summary References Chapter 14 Pharmacology of Psychotropic Medications Introduction Delusional Disorders (Psychoses): Schizophrenia and Antipsychotic Medications Antipsychotic Medications First-Generation Antipsychotics (FGAs) Second-Generation Antipsychotics Depression and Anxiety Monoamine Oxidase Inhibitors Adverse Reactions Drug–Drug Interactions Prescribing Considerations Tricyclic Antidepressants (TCAs) Adverse Reactions Drug–Drug Interactions Prescribing Considerations SSRIs and SNRIs Adverse Reactions Drug–Drug Interactions Prescribing Considerations Buspirone Adverse Reactions Drug–Drug Interactions Benzodiazepines Adverse Reactions Drug–Drug Interactions Prescribing Considerations Bipolar Disorder Mood Stabilizers First-Line Medications: Lithium, Valproic Acid, and Carbamazepine Lamotrigine Antipsychotic Drugs in Bipolar Disorder Prescribing Considerations for Drugs Used To Treat Bipolar Disorder Attention-Deficit Disorder and Attention-Deficit/Hyperactivity Disorder Stimulant Medications Adverse Effects Drug–Drug Interactions Nonstimulant Medications Adverse Reactions Drug–Drug Interactions Prescribing Considerations for Drugs Used for ADD/ADHD Sleep Disorders Sleep Hypnotic Drugs Adverse Reactions Drug–Drug Interactions Other Sleep Aids Prescribing Considerations for Sleep Aids Chapter Summary References Chapter 15 Pharmacology of Anesthetic Drugs Introduction Types of Anesthesia Local and Topical Anesthesia Adverse Effects Inhalational Anesthesia Drugs Used for Inhalational Anesthesia Nitrous Oxide Isoflurane Desflurane Sevoflurane Intravenous Anesthetics Induction Anesthetics Propofol Ketamine Etomidate Barbiturates Anesthetic Adjuncts Benzodiazepines Opioids Nonanesthetic Adjuncts Muscle Relaxants Acetylcholinesterase Inhibitors Anticholinergic Drugs Antiemetics Chapter Summary References Chapter 16 Pharmacology of Antimicrobial Drugs Introduction Antibacterials Sulfonamides Drug Interactions and Contraindications Nursing Considerations Tetracyclines Nursing Considerations a–Lactam Antibiotics Mechanism of Action Penicillins Drug Interactions and Contraindications Nursing Implications Cephalosporins Drug Interactions and Contraindications Nursing Implications Carbapenems Drug Interactions and Contraindications Nursing Considerations Monobactams Drug Interactions and Contraindications Nursing Considerations Beta-Lactamase Inhibitors Drug Interactions and Contraindications Aminoglycosides Drug Interactions and Contraindications Nursing Considerations Macrolides Drug Interactions and Contraindications Nursing Considerations Quinolones and Fluoroquinolones Drug Interactions and Contraindications Nursing Considerations Lincosamides Drug Interactions and Contraindications Nursing Considerations Vancomycin Drug Interactions and Contraindications Nursing Considerations Newer Anti-Infective Drugs for Resistant Infections Drug Interactions and Contraindications Quinupristin/Dalfopristin Linezolid Nursing Considerations Quinupristin/Dalfopristin Linezolid Antitubercular Drugs Drug Interactions and Contraindications Isoniazid (INH) Ethambutol Ethionamide Pyrazinamide (PZA) Rifampin Streptomycin Nursing Considerations Isoniazid Ethambutol Ethionamide Pyrazinamide Rifampin Streptomycin Antifungal Agents Drug Interactions and Contraindications Nursing Considerations Antiparasitic Agents Protozoal Infections Antiprotozoal Medications Drug Interactions and Contraindications Nursing Considerations Anthelmintic Agents Drug Interactions and Contraindications Nursing Considerations Antivirals Anti-Herpesvirus Agents Anti-Influenza Agents Anti-Hepatitis Agents Antiretroviral Agents Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Drug Interactions and Contraindications Nursing Considerations Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) Drug Interactions and Contraindications Nursing Considerations Protease Inhibitors (PIs) Drug Interactions and Contraindications Nursing Considerations Entry Inhibitors (EI) Integrase Strand Transfer Inhibitors (ISTIs) Chapter Summary References Glossary Index
