Pathophysiology : laboratory exercises

Content
 1/ Basic Methods
 1.1 Laboratory animals
 1.1.1 Division of laboratory animals
 1.1.2 The quality of animals 
 1.1.3 Ethics of work with experimental animals
 1.1.4 Some vertebrates used in experiments
 1.1.5 Manipulation with laboratory animals
 1.2 Laboratory protocol (report)
 1.3 Anesthesia
 1.3.1 General anesthesia
 1.3.2 Local anesthesia
 1.4 Injection technique
 1.5 Basic surgical instruments and sewing material
 1.6 Surgical technique in laboratory animals
 1.6.1 General principles
 1.6.2 Surgical sutures
 1.6.3 Cannulation of the vessels 1.6.4 Tracheostomia (Insertion of the tracheal cannula)1.7 Basic evaluation of measured data
 2/ General pathological physiology
 2.1 Skin resistance measurement 
 2.1.1 Changes of skin resistance --
galvanic reaction 
 2.2 Disturbances in thermoregulation --
fever
 3/ Blood
 3.1 Experimental hemolytic anemia
 3.2 Changes of coagulation due to peroral anticoagulants
 3.3 The effect of heparin on fibrin formation 
 3.4 Rumpel --
Leede test
 3.5 Direct test of phagocytosis by neutrophils
 4/ Circulation
 4.1 Examination of functional efficiencies of circulation
 4.2 Harvard step test 4.3 Letunov's test4.4 Telemetric observation of heart rate 
 4.5 Electrocardiogram (ECG) in pathological states of the heart. 
 4.5.1 Description of ECG curve
 4.5.2 Pathological changes on ECG curve
 4.5.2.1 Arrhythmias
 4.5.2.1.1 Disturbances of cardiac impulse initiation
 4.5.2.1.2 Disorders in impulse conduction
 4.5.2.2 ECG changes in inflammatory heart diseases
 4.5.2.3 ECG changes in ischemic heart disease
 4.5.2.4 ECG changes caused by pharmaceuticals
 4.5.2.5 Electrocardiogram changes in electrolyte disturbances
 4.5.2.6 Changes of the P wave
 4.5.2.7 Electric heart stimulation 4.6 Experimental disorders of the heart5/ Respiration
 5.1 Examination of pulmonary ventilation
 5.2 Influence of decreased partial pressure of oxygen
 5.3 Voluntary apnea
 6/ Digestion
 6.1 Investigation of saliva properties 
 6.2 Operation of the stomach --
insertion of stomach cannula
 7/ Metabolism and thermoregulation
 7.1 Obesity after stereotaxically performed hypothalamic lesion 
 7.2 Developmental dependence of thermoregulation 
 8/ Excretion
 8.1 Ureterostomia
 9/ Endocrinology
 9.1 Metabolic and circulatory changes in experimental thyroid dysfunction
 9.2 Adrenalectomy in rats 9.3 Castration in male rats10/ Nervous system
 10.1 Vestibular ataxia in a guinea pig
 10.2 Test of motor ability
 10.3 Recordings of bioelectrical brain activity in man --
electroencephalography
 10.4 EEG recordings --
evoked potentials (EP)
 10.5 Recordings of spontaneous end evoked ECoG in experimental animal. Experimental epilepsy