Pathogenesis and Mechanisms of Liver Cell Necrosis

Front Matter....Pages i-xi
Morphology of liver cell necrosis....Pages 1-14
Morphologic features of hepatocellular necrosis in human disease....Pages 15-24
Hydrolases and cellular death....Pages 25-35
Macromolecular syntheses and the maintenance of liver cell integrity....Pages 37-44
Quantitative aspects of biochemical mechanisms leading to cell death....Pages 45-56
Pathogenesis of hepatic necrosis caused by amanitin-albumin conjugate....Pages 57-67
Amanitin poisoning in the dog....Pages 69-74
Pathogenesis of frog virus 3 induced hepatitis in mice....Pages 75-86
Consequences of uridine triphosphate deficiency in liver and hepatoma cells....Pages 87-101
Ribosomes in dying liver cells....Pages 103-111
Histotopochemistry of glycogen and glycogen enzymes after allyl formate poisoning....Pages 113-117
The measurement of liver injury and protection, with special reference to paracetamol, dimethylnitrosamine and carbon tetrachloride....Pages 119-127
Hepatoprotective substances: a partial assessment....Pages 129-145
Liver morphology and enzyme release: further studies in the isolated perfused rat liver....Pages 147-162
Phalloidin, a membrane specific toxin....Pages 163-173
Morphological changes induced by phalloidin in the rat liver....Pages 175-192
Interaction of phalloidin with actin....Pages 193-197
Mechanism of necrosis induced by hepatotoxic bile acids....Pages 199-208
The role of lipid peroxidation in liver injury....Pages 209-223
Inhibition of protein synthesis in carbon tetrachloride-induced liver injury....Pages 225-238
Mechanism of hepatic necrosis induced by halogenated aromatic hydrocarbons....Pages 239-254
Back Matter....Pages 255-257