Pancreatic Cytopathology

Pancreatic\rCytopathology......Page 1
Copyright Page\r......Page 5
Foreword......Page 7
Series Preface......Page 9
Table of Contents\r......Page 11
Indications of Cytologic Sampling......Page 12
Methods of Sampling......Page 13
Complications......Page 14
Sample Preparation......Page 15
Performance......Page 18
Cytology of Normal Pancreas......Page 19
Contaminants......Page 23
Suggested Reading......Page 31
2 Pancreatic Cytopathology: A Pragmatic Approach......Page 33
Clinical and Imaging Data......Page 34
Solid/Mass Lesions......Page 35
Cystic Lesions......Page 40
Reporting......Page 42
3 Pancreatic Ductal Adenocarcinoma and Its Variants......Page 46
Diagnostic Criteria......Page 47
Well-Differentiated Adenocarcinoma......Page 49
Moderately and Poorly Differentiated Adenocarcinoma......Page 55
Variants of Pancreatic Ductal Carcinoma......Page 58
Ancillary Studies......Page 72
Differential Diagnosis and Pitfalls......Page 73
Clinical Management and Prognosis......Page 75
Suggested Reading......Page 76
Carcinogenesis of Pancreatic Ductal Carcinoma......Page 78
Oncogenes......Page 79
Tumor Suppressor Genes......Page 80
Proteins......Page 81
Oncogenes......Page 82
Tumor Suppressor Genes......Page 83
Other Tests, Future Directions......Page 84
Suggested Reading......Page 85
5 Acinar Cell Carcinoma......Page 86
Diagnostic Criteria......Page 87
Differential Diagnosis and Pitfalls (Table 5-2)......Page 94
Clinical Management and Prognosis......Page 97
Suggested Reading......Page 98
Diagnostic Approach......Page 99
Cytologic Findings......Page 100
Differential Diagnosis and Pitfalls......Page 102
Ancillary Studies (Table 6-3)......Page 103
Suggested Reading......Page 104
General Diagnostic Approach......Page 106
Diagnostic Criteria......Page 107
Ancillary Studies......Page 115
Differential Diagnosis and Pitfalls......Page 116
Clinical Management and Prognosis......Page 117
Suggested Reading......Page 118
8 Pancreatic Endocrine Tumors......Page 119
General Diagnostic Approach......Page 120
Diagnostic Criteria (Table 8-2)......Page 122
Differential Diagnosis (Table 8-3)......Page 131
Ancillary Studies (Table 8-4)......Page 133
Suggested Reading......Page 135
9 Cystic Mucus-Producing Neoplasia: IntraductalPapillary Mucinous Neoplasms and Mucinous Cystic Neoplasms......Page 136
General Diagnostic Approach......Page 137
Intraductal Papillary Mucinous Neoplasms......Page 143
Mucinous Cystic Neoplasms......Page 146
Differential Diagnosis and Pitfalls......Page 149
Ancillary Studies......Page 151
Suggested Reading......Page 153
General Diagnostic Approach......Page 155
Pseudocysts......Page 156
Infectious Cysts......Page 158
Squamous Cysts......Page 160
Serous Neoplasms......Page 165
Suggested Reading......Page 167
11 Inflammatory Disease of the Pancreas......Page 169
General Diagnostic Approach......Page 170
Chronic Pancreatitis......Page 171
Autoimmune Pancreatitis......Page 177
Clinical Management and Prognosis......Page 180
Suggested Reading......Page 181
12 Secondary Malignancies of the Pancreas......Page 182
Diagnostic Criteria and Differential Diagnosis......Page 183
Suggested Readings......Page 194
Index......Page 196