Paediatric Endocrinology: Management of Endocrine Disorders in Children and Adolescents

Series Preface
Volume Preface
Contents
About the Editors
Contributors
1 Disorders or Differences of Sex Development
	Introduction
		Typical Sex Development
		Terminology
	Causes of DSD
		Impaired Gonadal Development
			XY Individuals
				Complete and Partial Gonadal (Testicular) Dysgenesis
				Testis Regression/Anorchia
			XX Individuals
				Testicular and Ovotesticular DSD
				Ovarian Dysgenesis and Primary Ovarian Insufficiency
		Sex Chromosomal DSD
			45,X/46,XY (and Variants)
			46,XX/46,XY Chimerism (and Variants)
		Disturbances of Testicular Hormone Production or Action
			Impaired Biosynthesis
			Impaired Testosterone Action
		Virilization of an XX Individual
		Other Forms of 46,XY and 46,XX DSD
			Persistent Mullerian Duct Syndrome
			Hypospadias and Cryptorchidism
			Mayer-Rokitansky-Küster-Hauser Syndrome
			Endocrine Disrupters
	Management of DSD
		Initial Evaluation and Diagnostic Approach
			Examination
			Hormonal Work-Up
			Imaging
			Genetic Tests
		Sex Assignment, Gender Development, and Earl