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دانلود کتاب Our Genes, Our Choices. How genotype and gene interactions affect behavior
دانلود کتاب ژنهای ما ، گزینه های ما. چگونگی اثر متقابل ژنوتیپ و ژن بر رفتار
مشخصات کتاب
Our Genes, Our Choices. How genotype and gene interactions affect behavior
ویرایش:
نویسندگان: David Goldman (Auth.)
سری:
ISBN (شابک) : 9780123969521
ناشر: Academic Press
سال نشر: 2012
تعداد صفحات: 257
زبان: English
فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود)
حجم فایل: 4 مگابایت
قیمت کتاب (تومان) : 53,000
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توجه داشته باشید کتاب ژنهای ما ، گزینه های ما. چگونگی اثر متقابل ژنوتیپ و ژن بر رفتار نسخه زبان اصلی می باشد و کتاب ترجمه شده به فارسی نمی باشد. وبسایت اینترنشنال لایبرری ارائه دهنده کتاب های زبان اصلی می باشد و هیچ گونه کتاب ترجمه شده یا نوشته شده به فارسی را ارائه نمی دهد.
توضیحاتی درمورد کتاب به خارجی
-
In a bold, new integrative treatment of
the confusing facts and fictions about human behavior and
genetic determinism, David Goldman has provided a
user-friendly death to determinism and a rebirth of
genetic probabilism. He uses his breadth and depth of
neuroscience experience to optimize the necessary
reductionism for understanding violence, impulsivity,
depression, anxiety, and personality variations while
explaining the newest technologies of the researcher with
access to the laboratories of the National Institute of
Health and his colleagues.He
bravely confronts the numerous ethical dilemmas that
arise when dealing with new knowledge about our genetic
makeup and their implications for good and
evil.Drawing on his personal
exposure to mental disease in his own family, his
sensitive and energized writing reminds me of Sylvia
Nasars explication of ''A Beautiful Mind'', now giving
us a beautiful genome from a self-described ''behavioral
genomicist.'' We are treated to an insiders knowledge
about the work and hoopla about a gay gene and what may
be a better conceptualization closer to the
facts.Freed from the constraints of
journal writing with its 3 to 6 page shackles, Goldman
tackles the utility of race as a construct without
racism, communist ideology in science, insurance
discrimination against the mentally ill, free will, and
even pedophilia.His work provides
essential reading across the humanities, social and
medical sciences, and the courtroom. As fascinating as
any whodunit, he tries to account for the origins of our
behavioral outcomes, for good or for evil or for mental
anguish -was it genes, was it environment or culture, or
bad luck, or a conspiracy among some subset of culprits?
I wont give it away -read the book.Irving I. Gottesman Ph.D., Hon.FRCPsych, Bernstein
Professor in Adult Psychiatry & Senior Fellow, Department
of Psychology University of Minnesota & Sherrell J. Aston
Professor of Psychology Emeritus, University of
VirginiaOur Genes, Our Choices
grows out of a National Public Radio series led by its
author. It makes a compelling case for the relevance of
genetics to many vexing social problems that we face
today, including murder and addiction. This intriguing
book reflects the unique vision of David Goldman, M.D.,
Director of the Neurogenetics Laboratory of the
Intramural Research Program of the National Institute on
Alcohol Abuse and Alcoholism. As is evident in the book,
Dr. Goldman brings a keen intellect, critical thinking,
entertaining sense of humor, and a remarkable breadth of
culturalreferents. This book brings ones into the real
world challenges of molecular genetics, the technologies,
the administrative and ethical challenges, and the
startling and rapid progress. It highlight real
opportunities to shed light on a wide range of
maladaptive behaviors, but it also highlights the many
technical and conceptual challenges that currently limit
the impact of the advances in psychiatric genetics that
have been made to this point. Following the path laid out
in this book, one wrestles with many fundamental
questions of life. For example, if so much of our
behavior is an expression of genetic predispositions
expressed as we react to environmental stimuli, how can
we really be said to have free will? If we do not have
free will, how can we be culpable for our behavior? Does
being predisposed to murder absolve one from criminal
responsibility or point toward longer prison sentences
due to increased risk for repeating this behavior?
Goldman provides guidance that is both wise, cautious,
and entertaining in wrestling with these and other thorny
issues. Our Genes, Our Choices is an engaging and
important book as we seek to understand the broad
implications of recent advances in genetics for
society.John H. Krystal, M.D.,
Robert L. McNeil, Jr. Professor of Translational
Research, Chairman of the Department of Psychiatry, Yale
University School of MedicineGoldmans is pure gold in this endearing and
informative blend of personal insights and polished
professionalism that reflects on the basic nature of
human genetics and individuality. Goldman literally lives
and breaths his research. His passion for the topic comes
through with good humor while providing a didactic romp
through the complexities of both our genetics and our
brains. Entertaining and informative for the expert and
hobbiest alike, this is a must read for those who enjoy
contemplating unanswerable questions such as what makes
the human brain so unique and how behavior and cognition
are controlled, or not as the case may
be.At a time when
anti-intellectualism is at its height, Goldman
demonstrates a clear command of his material nicely
interwoven with every man stories and clever literary
references. There is truly something for everyone
here.Makes the case that
understanding ourselves is our greatest hope of surviving
ourselves, (i.e. we cannot evolve fast enough to meet the
rate of exponential challenge growth)Despite it being self-evidently obvious to most of us,
Goldman is willing to articulate that testosterone is
actualy a contributing factor to behavioral expression,
particularly those that involve aberrant impulsivity such
as aggression, murder, suicide. But he also does not
loose sight of the importance of context, environment,
experience, culture, pointing out that the predictive
value of each is slight, but nonetheless there is genuine
predictive value. If we have a modest predictor of cancer
risk its on the front page of the New York Times, but
people are much more squeamish about predictors of human
behavior and Goldman helps reduce the aversion with his
balanced, nuanced and yet accessible presentation. He
further exploits his refined analyses to reexamine the
panorama of mental health disorders and weave into their
description and interpretation a discussion of how
impulse control and disorders thereof are a common
component of multiple diseases. This serves two purposes,
it reminds us that there is a thin line between normal
and so-called aberrant thinking and behavior, and that
many mental health disorders have common underlying
phenotypes or are in fact many diseases with one
name.Additional gems include
Goldmans discussion of his own experiences in the legal
system and why the issue of genetic control of behavior
(read criminality) is a real and tangible one that can
change the course of lives today, as opposed to some
imagined science fiction future. He reminds us of
eugenics and the harm done in the past, but alerts us to
the current risks, and benefits, including genetic
studies and what they do and do not buy us. A valuable
review of the current technology used to study your genes
and use them for good or evil, assures the reader is
fully informed and no portion of the science is left
under the mantle of ''magic'' or too complicated for the
simple lay person to understand.He
leaves no subject untouched, tackling gun control, shoe
fetishes and sex addiction alike, even epigenetics, the
newest of the new in the study of genetic control of
behavior are subjects for which Goldman is well versed
and nicely capable of conveying to the
reader.Margaret McCarthy Ph.D.,
Professor, Departments of Physiology, Psychiatry and
Program in Neuroscience, University of Maryland School of
Medicine
فهرست مطالب
Content:
Front-matter, Pages i,iii
Copyright, Page iv
A Note on Gene and Protein Symbols, Pages vii-viii
Foreword, Page ix
Preface, Pages xi-xv
About the Author, Page xvii
Chapter 1 - The Neurogenetic Origins of Behavior, Pages 1-4
Chapter 2 - The Jinn in the Genome, Pages 5-14
Chapter 3 - 2B or Not 2B?, Pages 15-25
Chapter 4 - Stephen Mobley and His X-Chromosome, Pages 27-33
Chapter 5 - Dial Multifactorial for Murder: The Intersection of Genes and Culture, Pages 35-43
Chapter 6 - Distorted Capacity I: The Measure of the Impaired Will, Pages 45-60
Chapter 7 - Distorted Capacity II: Neuropsychiatric Diseases and the Impaired Will, Pages 61-77
Chapter 8 - Inheritance of Behavior and Genes “For” Behavior: Gene Wars, Pages 79-93
Chapter 9 - The Scientific and Historic Bases of Genethics: Who Watches the Geneticists and by What Principles?, Pages 95-107
Chapter 10 - The World is Double Helical: DNA, RNA and Proteins, in a Few Easy Pieces, Pages 109-122
Chapter 11 - The Stochastic Brain: From DNA Blueprint to Behavior, Pages 123-142
Chapter 12 - Reintroducing Genes and Behavior, Pages 143-152
Chapter 13 - Warriors and Worriers, Pages 153-162
Chapter 14 - How Many Genes Does it Take to Make a Behavior?, Pages 163-168
Chapter 15 - The Genesis and Genetics of Sexual Behavior, Pages 169-187
Chapter 16 - Gene By Environment Interaction, Pages 189-206
Chapter 17 - The Epigenetic Revolution: Finding the Imprint of the Environment on the Genome, Pages 207-212
Chapter 18 - DNA on Trial, Pages 213-220
Chapter 19 - Parents and Children: Neurogenetic Determinism and Neurogenetic Individuality, Pages 221-231
Chapter 20 - Summing Up Genetic Predictors of Behavior, Pages 233-234
Suggested Reading, Pages 235-242
List of Figures, Page 243
Glossary, Pages 245-248
Index, Pages 249-254
