Osteoimmunology: Interactions of the Immune and Skeletal Systems

Front Matter....Pages i-ix
Osteoimmunology: An Introduction....Pages 1-2
NF-κB and Inflammatory Bone Loss: “Alternative” Family Members Take Their Place at the Table....Pages 3-6
Adaptive Immune Responses and Bone....Pages 7-21
Intracellular Calcium Signaling for Osteoclast Differentiation....Pages 23-30
Lessons from Glucocorticoid Receptor Action in Bone: New Ways to Avoid Side Effects of Steroid Therapy....Pages 31-48
A Tak1/p38 Signaling Axis Regulates Runx2 Activity and Osteoblast Functions....Pages 49-56
Parathyroid Hormone: A Dynamic Regulator of Bone, Immune, and Hematopoietic Cells....Pages 57-71
Sphingosine-1-Phosphate and Chemokines in the Control of Osteoclast Precursors Migration Visualized by Intravital Multiphoton Microscopy....Pages 73-79
T Cells Mediate the Effects of PTH in Bone....Pages 81-90
The Relationship Between Inflammation, Destruction, and Remodeling in Chronic Joint Diseases....Pages 91-101
Regulation of RANKL-Induced Osteoclastogenesis by TGF-β....Pages 103-107
Effects of the Interleukin-1 Cytokine Family on Bone....Pages 109-114
DAP12 Regulates the Osteoclast Cytoskeleton....Pages 115-120
Osteoclast Determinants and Implications for Therapy....Pages 121-130
Back Matter....Pages 131-136