Organ Microcirculation: A Gateway to Diagnostic and Therapeutic Interventions

Front Matter....Pages 1-1
Importance of the Villus Microcirculation for Intestinal Absorption of Glucose....Pages 3-12
Oxygen Transport in the Microvessel Network....Pages 13-20
Beating-Heart Microvascular Imaging by High-Speed Video Microscope and SPring-8....Pages 21-32
The Laser Hot Balloon Catheter: a New Approach to Treating Atheromatous Lesions....Pages 33-34
Design and Modification of Nanoparticles for Blood Substitutes....Pages 35-41
Analysis of Angiogenic Profiles After Antiangiogenic Therapy by Colored Dye Extraction Microsphere Technique....Pages 43-45
Front Matter....Pages 47-47
Esophageal and Gastrointestinal Microcirculation: Essential for Mucosal Protection, a Target for Injury, and a Critical Component of Injury and Ulcer Healing....Pages 49-61
Microvascular Pathophysiology in Gastric Mucosal Inflammation Associated with Helicobacter pylori Infection....Pages 63-72
Ischemia/Reperfusion Injury in the Stomach: Role of Oxygen-Derived Free Radicals and Complement Regulatory System....Pages 73-78
Gastroduodenal Microcirculatory Response to Luminal Acid....Pages 79-88
Intracellular pH (pH i ) Measurement in Rat Duodenal Epithelium In Vivo Using SNARF-1....Pages 89-91
Prevention of Ethanol-induced Gastric Mucosal Microcirculatory Disturbances by Mild Irritant Through the Actions of Calcitonin Gene-Related Peptide and Prostaglandin I 2 in Rats....Pages 93-97
Role of Perforin and Granzyme B of Cytotoxic T Lymphocyte in the Onset of Peptic Ulcer Formation....Pages 99-105
Re-Evaluation of Microcirculatory Endothelial Cell as an Endocrine System of Leptin: Its Significance During Ulcer Healing and Helicobacter pylori Infection....Pages 107-113
Bile Nucleotides Exaggerate Ischemia-Reperfusion-Induced Epithelial Injury via P2Y, Not P2X Purinoceptor in Rat Jejunum....Pages 115-117
Prostaglandin E1 and a Serine Protease Inhibitor Protect the Gastric Microcirculation and Increase the Gastric Acid Secretion After Thermal Injury....Pages 119-122
Duodenal Blood Flow in Acute Portal Hypertension....Pages 123-125
Front Matter....Pages 127-127
Genetic Manipulation of Liver Sinusoidal Endothelial Cells....Pages 129-134
Basic Aspects of the Hepatic Microvascular System....Pages 135-136
Activation of Hepatic Stellate Cells: Anti-Adipogenic Differentiation?....Pages 137-144
Front Matter....Pages 127-127
Microvascular Derangement in Liver Transplantation....Pages 145-145
Regulation of Local Hepatic Oxygen Delivery Following Stress....Pages 147-154
Application of Superparamagnetic Iron Oxide for Hepatic Tumor Diagnosis....Pages 155-163
Roles of Thromboxane in Lipopolysaccharide-Induced Hepatic Microcirculatory Dysfunction in Mice....Pages 165-173
Changes of Hepatic Microcirculation in Acute Cholestasis....Pages 175-177
Front Matter....Pages 179-179
Microvascular Aspects of Ischemia-Reperfusion Injury....Pages 181-192
Analysis of Trigger Mechanisms for Inflammation in Cardiovascular Disease: Application to Shock and Multiorgan Failure....Pages 193-202
Selectin-Dependent Leukocyte Interactions with Vascular Surfaces....Pages 203-211
Lymphocyte Migration to the Intestinal Mucosa and its Relation to Mucosal Defense....Pages 213-221
Role for P-Selectin in Platelet Thrombus Formation Under Flow....Pages 223-224
Glomerular Microcirculation: Distinct Intracellular Mechanisms for Afferent and Efferent Arteriolar Tone....Pages 225-232
Role of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 (LOX-1) in Adenosine Diphosphate-Activated Platelet Adhesion to Human Brain Microvascular Endothelial Cells Under Flow In Vitro....Pages 233-237
Role of Oxidative Stress in Interaction Between Endothelial Cells and Platelets in Diabetes....Pages 239-241
T-Lymphocyte Migration is Differently Regulated in Appendiceal Lymph Follicles and Intestinal Peyer’s Patches....Pages 243-245
Cardiotonic Pill Improves Ischemia-Reperfusion-Induced Microcirculatory Disturbances in Rat Mesentery....Pages 247-249
Molecular Determinants of Dextran Sodium Sulfate Colitis-Induced Platelet Adhesion in Colonic Venules....Pages 251-253
Lymphatic Vessels as a Selective Administration Route of Antitumor Agent....Pages 255-257
Front Matter....Pages 259-259
The Heme Oxygenase-Carbon Monoxide System as a Regulator of Microvascular Function....Pages 261-265
Biological Characteristics of Lymphatic Endothelial Cells with Special Reference to Nitric Oxide and Lymphangiogenesis....Pages 267-273
How Does Inhaled Nitric Oxide Reach Peripheral Tissues?....Pages 275-282
Front Matter....Pages 259-259
Tumor Angiogenesis Regulated by Gaseous Molecules in Tumor Microenvironment: Oxygen, pH, and Nitric Oxide....Pages 283-290
Oxygen-Induced Cytoskeleton Rearrangement of Cultured Human Brain Microvascular Endothelial Cells....Pages 291-294