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دانلود کتاب Oral Biochemistry
دانلود کتاب بیوشیمی دهان
مشخصات کتاب
Oral Biochemistry
ویرایش:
نویسندگان: Min B.-M.
سری:
ISBN (شابک) : 9789819935956
ناشر: Springer
سال نشر: 2023
تعداد صفحات: 174
[175]
زبان: English
فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود)
حجم فایل: 9 Mb
قیمت کتاب (تومان) : 31,000
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توضیحاتی در مورد کتاب بیوشیمی دهان
توضیحاتی درمورد کتاب به خارجی
This book provides the reader with a comprehensive understanding of oral biochemistry by explaining the role of basic biochemistry and dentistry concepts and identifying their metabolic processes of soft tissues that comprise oral and maxillofacial anatomy. The book also discusses how metabolic abnormalities are related to the development of oral diseases. Readers will gain a comprehensive perspective on a variety of oral conditions and related metabolic abnormalities. Individual chapters are focused on crucial topics such as enamel, dentine, saliva, fluoride, and many more. The importance of evidence-based explanation and case study details are also highlighted. Oral biochemistry is the first book to be devoted entirely to this area, and it will be of interest to researchers, students, and practitioners.
فهرست مطالب
Cover Half Title Oral Biochemistry Copyright Dedication Preface Contents Author and Contributors 1. Characteristics and Importance of the Oral Cavity What Is Oral Biochemistry? Characteristics and Importance of Oral Cavity Digestive Function Antibacterial Function Buffering Action Lubrication Hygienic Action Taste Repair Control of Water Balance References 2. Enamel Microstructure of Enamel Unit Cell Crystal Enamel Rod (Prism) Inorganic Constituents of Enamel Isolation of Enamel, Dentine, and Cementum from Teeth Mechanical Method Flotation Technique Chemical Method Chemical Composition of Enamel Major Inorganic Components Calcium and Phosphate Bicarbonate (CO32-) Bicarbonate and Dental Caries Fluoride and Dental Caries Trace Elements Distribution of Fluoride in Tooth and Its Uptake Ratio Fluoride As an Inhibitor of Dental Caries Fluoride and Mottled Teeth Effects of Fluoride on Enamel Remineralization Ionic Substitution in Enamel Apatite Comparison of Synthetic Hydroxyapatite and Human Enamel Apatite Changes in Crystallinity After Heterogeneous Ionic Substitutions in Hydroxyapatite Precursors of Enamel Apatite Octacalcium Phosphate [Ca8H2(PO4)65H2O] Amorphous Calcium Phosphate Tricalcium Phosphate [Whitlockite, Ca3(PO4)2] Dicalcium Phosphate Dihydrate (Brushite, CaHPO4.2H2O) Organic Materials in Enamel Amelogenin Enamelin Ameloblastin (Amelin or Sheathlin) Tuftelin References 3. Dentine Dentine Structure Chemical Composition of Dentine Inorganic Components of Dentine Organic Constituents of Dentine Physicochemical Properties and Biosynthesis of Collagen Physicochemical Properties of Collagen Amino Acid Composition of Collagen Protein Structure of Collagen Basic Structure of Tropocollagen Gelatinization of Collagen Collagen Biosynthesis Biosynthesis of Pro-α-Chain Hydroxylation of Proline and Lysine Residues in Pro-α-Chain Glycosylation of Certain Hydroxylysine Residues Procollagen Formation Transport and Secretion of Procollagen Procollagen-Collagen Conversion (Cleavage of Pro-peptide) Fiber Formation and Polymerization Formation of Cross-Links Collagen Degradation Collagenase Gelatinase Diseases Related to Collagen Synthesis Elastic Fibers Non-collagenous Proteins Non-collagenous Proteins in Bones and Dentine Osteocalcin (Bone Gla Protein) Osteonectin (SPARC, Culture Shock Protein, BM-40) Bone Sialoprotein (BSP) Osteopontin (Spp-I, BSP-I) Bone Sialoprotein-II (BSP-II) Bone Acidic Glycoprotein-75 (BAG-75) Dentine Matrix Protein-1 (Dmp-1) Tetranectin Thrombospondin Fibronectin Vitronectin Proteoglycan Large Proteoglycans: Aggrecan and Versican Small Proteoglycans: Decorin and Biglycan Hyaluronic Acid (Hyaluronan) Dentine-Specific Non-collagenous Proteins Phosphophoryn (Dentine Matrix Protein-1) Dentine Sialoprotein Extrinsic Non-collagenous Proteins Serum Protein Soluble Factors References 4. Pulp Composition of Pulp Pulp Cells Odontoblasts Fibroblasts Immune Cells Undifferentiated Cells Changes in the Distribution of Pulp Cells Extracellular Matrix of the Dental Pulp Fibrous Proteins Ground Substance Metabolism of the Pulp Pulp Repair and Related Signaling References 5. Calcification of Bones and Teeth Calcified Biological Tissue Function and Structure of Bone Chemical Composition of Bone and Bone Tissue Cells Inorganic Components of Bone Organic Components of Bone Cells in Bone Tissue Osteoblasts Osteocytes Osteoclasts Bone Lining Cells Growth and Remodeling of Bone Development and Growth of Bone Bone Remodeling Age-Dependent Bone Changes Local Factors Causing Bone Remodeling Local Factors Regulating Osteoblast Differentiation Local Factors Regulating Osteoclast Differentiation Calcium and Phosphorus Metabolism Calcium Metabolism Homeostasis of Plasma Calcium Calcium Absorption Factors Affecting Calcium Absorption Phosphorus Metabolism Hormones That Affect Calcium and Phosphorus Metabolism Parathyroid Hormone Regulation of the Activity of Parathyroid Hormone Action of Parathyroid Hormone Calcitonin 1,25-Dihydroxycholecalciferol [1,25(OH)2D3] Biosynthesis and Activation of Vitamin D3 Action of 1,25-Dihydroxycholecalciferol [1,25(OH)2D3] Sex Hormones Growth Hormones Glucocorticoids Thyroid Hormone Factors Affecting Bone Metabolism Disorders of Calcium and Phosphorus Metabolism Hyperparathyroidism Hypoparathyroidism Mechanism of Calcification Simple Spontaneous Precipitation Hypothesis Alkaline Phosphatase Hypothesis Glycolysis and Alkaline Phosphatase Hypothesis Seeding Theory Hole-Zone Theory Matrix Vesicle-Induced Calcification Theory Generation of Matrix Vesicles Mechanism of Matrix Vesicle-Induced Calcification Current Concepts Regarding the Calcification Mechanism Growth and Maturation of Apatite Crystals Characteristics of Calcification in Teeth References 6. Oral Mucosa and Gingiva Structure and Function of the Oral Mucosa and Gingiva Epithelial Structure of Oral Mucosa and Gingiva Connective Tissue Structure of Oral Mucosa and Gingiva Function of the Oral Mucosa Metabolism of Gingiva Composition of Gingiva Collagen Proteoglycan Non-collagenous Proteins Lipid Keratin Metabolism of the Gingiva Gingivitis Matrix Metalloproteinases (MMPs) Changes in Gingival Epithelium and Connective Tissue Destruction of Gingival Tissue References 7. Saliva Structure and Vascular System of Salivary Glands Structure of Salivary Glands Vascular System of Salivary Glands The Nervous System of the Salivary Gland Brain Functions Involved in Saliva Secretion (Central Autonomic Network) Peripheral Autonomic Nervous System of Salivary Glands Mechanism of Salivary Secretion Secretion of Inorganic Substances in Primary Saliva Secretion of Organic Substances in Primary Saliva Transportation Through Intercellular Junctions Autonomous Properties of Myoepithelial Cells Modification of Primary Saliva by the Duct System Properties of Saliva Functions of Saliva Constituents of Saliva Inorganic Constituents Hydrogen Ion Calcium and Phosphate Bicarbonate Fluoride Thiocyanate Sodium, Potassium, Magnesium, and Chloride Other Ions Organic Constituents α-Amylase Mucin Antibacterial Salivary Proteins Lactoferrin (Red Iron-Binding Protein) Lactoperoxidase Lysozyme Immunoglobulin sIgA IgM IgG Salivary Proteins Associated with Calcification Anionic Proline-Rich Proteins Statherin Other Salivary Proteins Histatin Cystatin Buffering Capacity of Saliva Bicarbonate Buffer System Phosphate Buffer System Salivary Protein Buffer System Ammonia Buffer System Factors Affecting Saliva Composition Relative Contributions of the Salivary Glands Salivary Secretion Rate Nature of Stimuli References 8. Acquired Enamel Integuments: Pellicle, Plaque, and Calculus Acquired Pellicle Formation of Acquired Pellicle Mechanism of Acquired Pellicle Formation Function of Acquired Pellicle Dental Plaque (Oral Biofilm) Mechanism of Dental Plaque Formation Adhesion and Colonization of Oral Bacteria on Acquired Pellicle Formation of Plaque Matrix Formation of Plaque Matrix Without Food Intake Formation of Plaque Matrix After Food Intake Dextran Mutan Levan Intracellular Glycogen-Like Polysaccharides Sugar As a Cariogenic Factor Characteristics of Mature Dental Plaque Dental Plaque Metabolism and Oral Diseases Sugar Metabolism and Acid Production Sugar Metabolism Stephan Curve Nitrogen Metabolism and Base Production Decarboxylation Reaction Composition of Dental Plaque Chemical Composition of Dental Plaque Function of Fluoride in Dental Plaque Effect of Fluoride on Sugar Metabolism of Plaque Bacteria Plaque Bacteria Dental Plaque and Periodontal Disease Control of Dental Plaque Mechanical Method (Tooth Brushing) Chemical Method Stannous Fluoride (SnF2) Lanthanum Ion (La3+) Dextranase and Mutanase Chlorhexidine Antibiotics Lectin Dental Calculus Mechanism of Dental Caries Theories of Caries Development The Chemicoparasitic Theory The Proteolytic Theory The Proteolysis-Chelation Theory The Endogenous Theory The Glycogen Theory The Organotropic Theory The Biophysical Theory Alternative Sweeteners Xylose Palatinose Sorbitol Maltitol Xylitol Fructooligosaccharides and Coupling Sugars Stevioside Monellin Aspartame Saccharin References 9. Functions of Fluoride in the Oral Cavity Fluoride Effects of Fluoride on Enamel Remineralization Inhibition of Caries by Fluoride Mottled Teeth Effects of Fluoride on Plaque Bacterial Metabolism Uses of Fluoride for the Prevention of Dental Caries References Index
