One Health Meets the Exposome: Human, Wildlife, and Ecosystem Health

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	One Health Meets the Exposome: Human, Wildlife, and Ecosystem Health
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	Copyright
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	Dedication
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	Preface
		The Opportunity
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	Acknowledgments
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	1. Introduction
		Humanity in context
		Global challenges
			Human population growth, resource use, and migration
			Human health and its determinants
			Biodiversity loss and land use change
			Climate change, ecosystem health, and sustainability
			Culture, society, science, and policy
		Defining the conceptual framworks
			One Health
			The Exposome
		Comparing the two concepts through the literature
		References and additional resources
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	2. Human Health
		Humans: history, distribution, and demographics
			Human health and burden of disease
		Overview of One Health and the Exposome
		Ingredients necessary for human health
		Global challenges to human health
			Challenge #1: Population growth and demographic transition
				One Health and Exposome views on population growth, demographic transition, and human health
				What is not captured in either framework?
			Challenge #2: Novel diseases
				One Health and Exposome views on novel diseases and human health
				What is not captured in either framework?
			Challenge #3: Anthropogenic pollution
				One Health and Exposome views on anthropogenic pollutants and human health
				What is not captured in either framework?
			Challenge #4: Climate change
				One Health and Exposome views on climate change and human health
				What is not captured in either framework?
			Challenge #5: Social and economic disparities
				One Health and Exposome views on social and economic disparities and human health
				What is not captured in either framework?
		Conclusions
		References
		Additional resources
		Further reading
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	3. Domestic Animal Health
		Domestic animals: history, distribtion, and role in human communities
		Overview of One Health and the Exposome
		Ingredients necessary for animal health
		Global challenges to domestic animal health
			Challenge #1: Industrial agriculture
				One Health and Exposome views on industrial agriculture and domestic animal health
				What is not captured in either framework?
			Challenge #2: Climate change
				One Health and Exposome views on climate change and domestic animal health
				What is not captured in either framework?
			Challenge #3: Domestic animal–wildlife interactions and conflicts
				One Health and Exposome views on interactions and conflicts with wildlife and domestic animal health
				What is not captured in either framework?
		Conclusions
		References
		Additional resources
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	4. Wildlife Health
		Wildlife: diversity, distribution, history, and health
		Overview of One Health and the Exposome
		Ingredients necessary for wildlife health
		Global challenges to wildlife health
			Challenge #1: Habitat loss and encroachment of the built environment into wildlife areas
				One Health and Exposome views on habitat loss, encroachment of the built environment, and wildlife health
				What is not captured in either framework?
			Challenge #2: Conflict with humans and interactions with domestic species
				One Health and Exposome views on human-wildlife conflict and wildlife health
				What is not captured in either framework?
			Challenge #3: Wildlife trade and overharvesting
				One Health and Exposome views on wildlife trade, overharvesting, and wildlife health
				What is not captured in either framework?
			Challenge 4: Anthropogenic pollution
				One Health and Exposome views on anthropogenic pollution and wildlife health
				What is not captured in either framework?
			Challenge #5: Climate change
				One Health and Exposome views on climate change and wildlife health
				What is not captured in either framework?
			Challenge #6: Invasive species
				One Health and Exposome views on invasive species and wildlife health
				What is not captured in either framework?
		Conclusions
		References
		Additional resources
		Further reading
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	5. Ecosystem Health on a Global Scale
		Ecosystems: diversity, distribution, health, and management
		Overview of One Health and the Exposome
		Ingredients necessary for ecosystem health
		Global challenges to ecosystem health
			Challenge 1: Anthropogenic pollution
				One Health and Exposome views on anthropogenic pollution and ecosystem health
				What is not captured in either framework?
			Challenge 2: Climate change
				One Health and Exposome views on climate change and ecosystem health
				What is not captured in either conceptual framework?
			Challenge 3: Human consumption driving habitat conversion and resource utilization
				One Health and Exposome views on human consumption, resource utilization, and ecosystem health
				What is not captured in either framework?
		Conclusions
		References
		Additional resources
		Further reading
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	6. Case Studies: One Health and the Exposome at Work
		Case study #1: United States Agency for International Development’s Emerging Pandemic Threats program
			Virus surveillance, discovery, and distribution
			Human behavior investigations
			PREDICT outbreak response
			Predicting future spillovers
				One Health—Exposome connection to PREDICT and RESPOND
		Case study #2: Deepwater Horizon oil spill
			Immediate response
			Timeline for funding, actions, and overall accomplishments
				Ecosystem health effects
				Wildlife health effects
				Human health effects
				One Health—Exposome connections to the Deepwater Horizon oil spill
		Case study #3: Smoke, from indoor cooking fires to tobacco use
			Indoor cooking by traditional cookstoves and open fires
			Tobacco smoke
				Health effects of smoking
				Recent history and changes in cigarette smoking
				One Health-Exposome connections to smoke inhalation, the use of traditional cookstoves, and cigarette smoking
		Conclusions
		References
		Additional resources
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	7. Bridging the Exposome and One Health Conceptual Frameworks to Achieve Global One Health and Reduce Exposome Load
		Effects of global challenges on ingredients necessary for health
		“Take aways” from previous chapters
		Review of the two frameworks
		Intersections of existing frameworks with One Health and the Exposome
		One Health and Exposome frameworks address different challenges
		Utility of One Health and Exposome frameworks to address global challenges
		A cohesive conceptual framework requires both One Health and the Exposome
		References
		Further reading
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	Index
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	Appendix 1