Nucleic Acids in Immunology: Proceedings of a Symposium Held at the Institute of Microbiology of Rutgers, The State University

Front Matter....Pages i-xvii
Front Matter....Pages 1-1
Reading the Helix Backwards....Pages 3-4
Methylated Bovine Serum Albumin as a Carrier for Oligo- and Poly-Nucleotides....Pages 5-17
The Production of Antibodies to Mononucleotides, Oligonucleotides, and DNA....Pages 18-31
Specific Antibodies to Polynucleotide Complexes and their Reaction with Nucleic Acids: Importance of the Secondary Structure of the Antigen....Pages 32-46
Specificity in the Reaction between Anti-Pyrimidine Nucleoside Antibodies and DNA....Pages 47-57
Antibodies to the Terminal Moieties of Guanine Mononucleotides and Guanine-Containing Dinucleotides....Pages 58-66
Front Matter....Pages 77-77
Formation and Isolation of Antibodies Specific for Nucleotides....Pages 79-87
The Reaction of Anti-Deoxyribonucleic Acid Sera with Nucleoside and Nucleotide Conjugates....Pages 88-97
The Various Types of DNA Antibodies in Lupus Sera....Pages 98-113
DNA and Nucleoprotein Determinants for Systemic Lupus Erythematosus Sera....Pages 114-124
Cellular Phases of the Immune Response Following Immunization with Mammalian and Bacterial Ribosomes....Pages 125-146
Front Matter....Pages 155-155
Immunological Evidence for the Existence of Thymine Dimers in Ultraviolet Irradiated DNA....Pages 157-164
Immunological Evidence for the Identity of a Photoproduct Formed during Photooxidation of DNA with Methylene Blue, Rose Bengal, Thionin, and Acridine Orange....Pages 165-173
Use of Anti-RNA Antibodies in the Study of the Structure of Polynucleotides and Ribosomal Particles....Pages 174-200
Inhibition of Bacterial Transformation by Nucleic Acid-Specific Antibodies....Pages 201-221
Effects of Anti-Hapten Antibodies on the Biological Activities of Nucleic Acids....Pages 222-247
Use of Fluorescein-Labelled Anti-Nuclear Antibodies in the Study of Chromosomal Structure....Pages 248-270
Front Matter....Pages 275-275
The Genetic Control of the Immune Response to Hapten-Poly-L Lysine Conjugates in Guinea Pigs....Pages 277-287
The Relationship of the Hapten to the Carrier in the Induction and Specificity of the Immune Response....Pages 288-300
Importance of Immunogenicity of the Carrier in Inducing a Response against Carrier-Synthetic Polymer Aggregates....Pages 301-318
Front Matter....Pages 275-275
Specificity of the Immune Response as a Function of the Carrier....Pages 319-329
The Role of Conformation in the Structure of Antigenic Sites....Pages 330-337
Front Matter....Pages 345-345
Stimulation of Antibody-Forming Cells by Oligonucleotides of Known Composition....Pages 347-363
Influence of Oligonucleotides of Known Composition on Rates of DNA Synthesis in Pneumococci....Pages 364-378
Enhancement of Antibody Formation by Nucleic Acids and their Derivatives....Pages 379-385
Restoration of Immunologic Capacities in Irradiated Animals by Nucleic Acids and their Derivatives....Pages 386-403
Nucleic Acids and Induction of Antibody Synthesis in Inhibited Systems....Pages 404-413
Induction of an Allogeneic-Like Inhibition by Means of DNA Obtained from Untreated Cells....Pages 414-428
Front Matter....Pages 437-437
Antibody Formation Initiated in Vitro with RNA and RNA-Antigen Complexes....Pages 439-446
Roles of DNA and RNA in the Antibody Response....Pages 447-470
The Antigen-RNA Complex of Macrophages....Pages 471-486
On the Role of Antigen Fragments and RNA in the Immune Response of Rabbits to a Soluble Antigen....Pages 487-504
The Nature of Immunogenic RNA-Antigen Complexes in Immune and Tolerant Mice....Pages 505-526
Stimulation of Anti-Tumor Activity of the Host with RNA from Immune Lymphocytes....Pages 527-534
Front Matter....Pages 545-545
Fractionation of RNA Capable of Transferring Transplantation Immunity....Pages 547-559
Induction of Accelerated Graft Rejection and Enhanced Graft-Versus-Host Reaction with RNA from Lymphoid Organs of Animals Immunized with Allogeneic Tissues....Pages 560-572
Unique Species of RNA in Peritoneal Cells Exposed to Different Antigens....Pages 573-589
Studies in Vitro on Immunoglobulin Biosynthesis....Pages 590-604
Synthesis and Assembly of Immunoglobulin....Pages 605-613
On the Role of Nucleic Acids as Genes Conferring Precise Chemospecificity to Differentiated Cell Lines....Pages 614-643
Front Matter....Pages 545-545
Studies on the Multiple Isoaccepting Transfer Ribonucleic Acids in Mouse Plasma Cell Tumors....Pages 644-659
Isolation and Characterization of RNA Produced in Response to Antigen....Pages 660-663
Front Matter....Pages 669-669
The Molecular Biology of Expectation....Pages 671-715
Back Matter....Pages 717-724