New Developments in Biosciences: Their Implications for Laboratory Animal Science: Proceedings of the Third Symposium of the Federation of European Laboratory Animal Science Associations, held in Amsterdam, The Netherlands, 1–5 June 1987

Front Matter....Pages I-XXI
Opening Address: The Future of Laboratory Animal Use....Pages 1-6
The Acquired Immunedeficiency Syndrome in Man....Pages 7-10
Feline Acquired Immunodeficiency Syndromes....Pages 11-15
Immune Deficiency Syndrome in Rodents: The Nude Rat....Pages 17-28
Animal Welfare — Common Interest....Pages 29-30
Laboratory Animal .... Science — Service — Use....Pages 31-33
Laboratory Animal Science in Czechoslovakia....Pages 35-40
On the Ethology of Pain, its Experience and Expression....Pages 41-46
Pain in Neonates....Pages 47-51
Endorphins and Pain....Pages 53-57
Effects of Exogenous Pain Relieving Substances on Experimental Results....Pages 59-61
Veterinary Care at the Primate Center TNO....Pages 63-66
Developing Housing Facilities for Rhesus Monkeys: Prevention of Abnormal Behaviour....Pages 67-70
Microbiological Quality Assurance and Quality Assessment of Laboratory Animals....Pages 71-74
Centralisation — Decentralisation: Failure — Success....Pages 75-80
The Effect of Homogenization and Pasteurization on the Allergenicity of Bovine Milk Analysed by a Murine Anaphylactic Shock Model....Pages 81-86
Murine Passive Cutaneous Anaphylaxis Test (PCA) for the “All or None” Determination of Allergenicity of Bovine Whey Proteins and Peptides....Pages 87-92
Phenotypic and Patho-Morphological Characteristics in a Half-Sib-Family of Transgenic Mice Carrying Foreign MT-HGH Genes....Pages 93-98
The Housing and Handling of Marmosets and Tamarins Infected with Aids and Other Retroviruses....Pages 99-103
Long-Term Observation of Litter Intervals in Permanently Monogamous Mated Han:NMRI Mice....Pages 105-109
Genital Inflammation in Male Mice. A Microbiological Study....Pages 111-116
Microbial Assessment of a Single Fumigation by Formaldehyde of a Multi-Level Animal Facility....Pages 117-119
Mechanisms of Natural Selection Maintaining in Groups of Highly Standardized Mice and Rats, Influence on Infection Resistance....Pages 121-126
Provocation of Latent Infections....Pages 127-131
Introduction to Recombinant DNA Technology....Pages 133-141
DNA Hybridization as a Tool in Diagnosing Infectious Diseases. Comparison with Other Methods....Pages 143-146
Embryo Transfer and Manipulation....Pages 147-162
Strain Preservation of Rodent Embryos. Possibilities and Limitations....Pages 163-173
The Generation of Transgenic Animals and Their Use in Fundamental Research....Pages 175-183
On the Inheritance of Blood Characters in Mice....Pages 185-189
Investigating Genetic Variability between the MHS Hypertensive Strain of Rats and its Normotensive Control, MNS....Pages 191-196
Gene Mapping and Linkage Homology....Pages 197-201
A New Method to Produce Artificial Monozygotic Twins in Mice....Pages 203-208
Genetic Analysis of Multigenic Traits Using the Recombinant Congenic Strains....Pages 209-214
Acute Dermal Toxicity: Morphological Response of the Hairless Mice Skin Organ Culture....Pages 215-220
The Dutch Rabbit in Toxicity Testing Chemical — Induced Creatine Kinase Release; a Species- and Strain-Specific Response?....Pages 221-224
Intertrial — Interval in the “Water Escape Test” in Mice....Pages 225-230
Behaviour, Housing and Welfare of Non-Human Primates....Pages 231-237
Housing and Welfare of Laboratory Rodents....Pages 239-244
Housing Conditions and Experimental Results....Pages 245-254
Basis of the European Guidelines: Facts or Intuition?....Pages 255-265
Gnotobiotic Animals in Nutrition Research....Pages 267-276
Animal Models for Cholesterol Metabolism Studies....Pages 279-288
Animal Models in Hemostasis and Thrombosis....Pages 289-294
What’s your diagnosis? Mice with ulcerating Lesions on the Nose, Limbs and/or Tail ....Pages 295-298
Spontaneous Hyperplasia of the Endometrium in the rabbit....Pages 299-303
Monkey Graffity (environmental deficiency, boredom or artistic drive?)....Pages 305-309
Marking of African clawed toads ( Xenopus laevis ). Improvement of a skin autograft technique....Pages 311-316
Changes in Energy Intake, Body Weight Gains, Average Feed Efficiency and Some Plasma Hormone Levels in Dogs from Different Environments....Pages 317-324
Serum Concentrations of Vitamins A, D and E of Growing Beagles Fed Commercial Dog and Fox Diets....Pages 325-330
Integration of HGH Gene in Transgenic Mice and Transmission to Next Generation....Pages 331-336
Attempts to Produce Transgenic Rabbits Carrying MTI-HGH Recombinant Gene....Pages 337-341
Electrofusion of Early Mammalian Embryo Cells....Pages 343-347
Passive Infrared Movement Detector, a New Equipment to Monitor Motor Activity of Small Rodents in Normal Cages....Pages 349-352
Establishment of a SPF Population of Cricetulus griseus....Pages 353-358
Chronic Phlorizin Intoxication in Adipose Mutant Mice C57BL/KS db/db and in Normal Conrols....Pages 359-363
Plasma α-Amylase and Lipase Activities in Dogs with Variations in Food Composition and Availability....Pages 365-371
Locomotor Activity of a Behavior Mutant in NMRI Mice....Pages 373-374
The application of embryo transfer and cryopreservation to commerciel laboratory animal breeding....Pages 375-378
Serological Following of a Laboratory Rat Breeding Contaminated with Respiratory Viruses During 1981–1986....Pages 379-384
Eradication of Encephalitozoonosis in Rabbit Breeding Colonies by Carbon Immunoassay....Pages 385-387
Spontaneous Murine Hemosiderosis, A Model for Human Hemochromatosis?....Pages 389-392
In Vitro Adhesion of K88 Positive E. Coli to Intestinal Villi of Just-weaned Piglets....Pages 393-397
The Effects of Gentling on Open-field Behaviour of Rats....Pages 399-403
Blastomere Karyotyping: A Direct Method for Producing Mouse Trisomy 16 ↔ Diploid Aggregation Chimeras as an Animal Model of Human Down’s Syndrome....Pages 405-408
A Proposed Species Difference in the Renal Excretion of Perfluoro Octanoic Acid in the Beagle Dog and Rat....Pages 409-412
Measurement of Orthostatic Responses in Conscious Dogs....Pages 413-417
Oral 65Zn Loading Test in Rats Fed Iri-Ob Diet with Various Zn Concentrations....Pages 419-423
Mortality and Tumour Incidence of BDII/Han Rats....Pages 425-429
Assessment of Discomfort Induced by Orbital Puncture in Rats....Pages 431-436
Effect of Morphinomimetics in Different Pain Tests....Pages 437-442
Prevention of Early Deaths in Mice Contaminated with Gram Negative Enteric Bacteria and Fungus Following Irradiation....Pages 443-446
Detection of Mycoplasma neurolyticum in a colony of inbred mice: clinically silent infection....Pages 447-448
Effects of Handling and Transportation Stress on Rodents....Pages 449-457