Neurochemical Correlates of Cerebral Ischemia

Front Matter....Pages i-xxi
Introduction Current Biochemical and Molecular Approaches to the Study of Cerebral Ischemia....Pages 1-8
Metabolic Correlates of Focal Ischemia....Pages 9-39
Role of Pyruvate Dehydrogenase in Ischemic Injury....Pages 41-57
Disturbances of Protein and Polyamine Metabolism After Eversible Cerebral Ichemia....Pages 59-83
Oxygen Dependence of Neuronal Metabolism....Pages 85-101
Dysmetabolism in Lipid Brain Ischemia....Pages 103-116
Involvement of Calcium, Lipolytic Enzymes, and Free Fatty Acids in Ischemic Brain Trauma....Pages 117-138
Arachidonic Acid Lipoxygenase Products Participate in the Pathogenesis of Delayed Cerebral Ischemia....Pages 139-159
Biochemical Changes and Secondary Tissue Injury After Brain and Spinal Cord Ischemia....Pages 161-181
Free Fatty Acid Liberation in the Pathogenesis and Therapy of Ischemic Brain Damage....Pages 183-218
Cerebral Ischemia and Polyphosphoinositide Metabolism....Pages 219-244
Protection Against Ischemic Brain Damage by Excitatory Amino Acid Antagonists....Pages 245-263
Acute Alterations in Phosphoinositide Turnover....Pages 265-275
New Insights into the Role of Oxygen Radicals in Cerebral Ischemia....Pages 277-294
Biochemical Factors and Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma....Pages 295-320
Modulators of Neural Cell Signaling and Triggering of Gene Expression following Cerebral Ischemia....Pages 321-333
Cellular and Metabolic Significance of Cellular Acid-Base Shifts in Human Stroke....Pages 335-357
Back Matter....Pages 359-367