Neurobiology of Cytokines

Content: 
Methods in Neurosciences
Page ii

Front Matter
Page iii

Copyright page
Page iv

Contributors to Volume 16
Pages ix-xii

Preface
Pages xiii-xiv
ERROL B. DE SOUZA

Methods in Neurosciences
Page xv

1 - Pharmacological, Biochemical, and Molecular Biological Studies on Cytokine Receptors
Pages 3-32
Steven K. Dower

2 - Genetic Regulation and Activities of an Interleukin 1 Receptor Antagonist Protein
Pages 33-48
Donald B. Carter, Ann E. Berger, Daniel E. Tracey

3 - Identification of Intracellular Mediators of the Actions of Cytokines: Identifying Proteins Involved in Kinase Signaling Pathways
Pages 49-66
Gerald A. Evans, Hallgeir Rui, William L. Farrar

4 - Measurement of Transport of Cytokines across the Blood–Brain Barrier
Pages 67-77
William A. Banks, Abba J. Kastin

5 - In Situ Hybridization Techniques for Localization of Interleukin 1 and Interleukin 1 Receptor Antagonist mRNA in Brain
Pages 81-99
Ma-Li Wong, Philip W. Gold, Júlio Licinio

6 - Immunocytochemical Methods for Localization of Cytokines in Brain
Pages 100-111
John A. Olschowka

7 - Localization of Type I Interleukin 1 Receptor mRNA in Brain and Endocrine Tissues by in Situ Hybridization Histochemistry
Pages 112-127
Emmett T. Cunningham Jr., Errol B. De Souza

8 - Identification, Autoradiographic Localization, and Modulation of Interleukin 1 Receptors in Brain-Endocrine-Immune Axis: Methodology and Overview
Pages 128-154
Toshihiro Takao, Dimitri E. Grigoriadis, Errol B. De Souza

9 - C-fos-Based Functional Mapping of Central Pathways Subserving Effects of Interleukin 1 on the Hypothalamo–Pituitary–Adrenal Axis
Pages 155-172
Anders Ericsson, Paul E. Sawchenko

10 - Anatomical and Functional Approaches to Study of Interleukin 2 and Its Receptors in Brain
Pages 173-184
David Seto, Uwe Hanisch, Françoise Villemain, Alain Beaudet, Rémi Quirion

11 - Endocrine Aspects of Neuroimmunomodulation: Methods and Overview
Pages 187-210
Samuel M. McCann, Ljiljana Milenkovic, M. Carmen Gonzalez, Krzysztof Lyson, Sharada Karanth, Valeria Rettori

12 - Determining Role and Sources of Endogenous Interleukin 1 in Pituitary–Adrenal Activation in Response to Stressful and Inflammatory Stimuli
Pages 211-231
Frank Berkenbosch, Nico Van Rooijen, Fred J.H. Tilders

13 - In Vivo and in Vitro Methods for Studying Effects of Cytokines on Adrenocorticotropic Hormone, Arginine Vasopressin, and Oxytocin Secretion
Pages 232-247
Junichi Fukata, Hajime Segawa, Yoshiyuki Naito, Norihiko Murakami, Hiromasa Kobayashi, Osamu Ebisui, Takeshi Usui, Hiroo Imura

14 - In Vivo and in Vitro Models for Evaluating Effects of Interleukin 1 on Hypothalamic–Pituitary–Gonadal Axis
Pages 248-268
Pushpa S. Kalra, Satya P. Kalra

15 - Methodological Evaluation of Sites and Mechanisms of Action Involved in Neuroendocrine Effects of Cytokines
Pages 269-293
Akira Arimura, Paul E. Gottschall

16 - In Vivo and in Vitro Methods for Studying Effects of Tumor Necrosis Factor on Pituitary Cells
Pages 294-301
Alberto E. Panerai, Vittorio Locatelli, Paola Sacerdote

17 - Determination of Direct Effects of Cytokines on Release of Neuropeptides from Rat Hypothalamus by an in Vitro Method
Pages 302-326
Ashley Grossman, Stylianos Tsagarakis, Marta Korbonits, Alfredo Costa

18 - Effects of Interleukin 1 on β-Endorphin Secretion in AtT-20 Pituitary Cells: Methods and Overview
Pages 327-342
Mirela O. Făgărăăan

Index
Pages 343-352