Neurobiology of Acetylcholine

Front Matter....Pages i-xii
Front Matter....Pages 1-1
Distribution of Cholinergic Neurons in Human Brain....Pages 3-16
Development of the Acetylcholine Receptor Clusters Induced by Basic Polypeptides in Cultured Muscle Cells....Pages 17-25
Characteristics of Cholinergic Synapses in Neuroblastoma Myotube Co-Cultures....Pages 27-46
Identification of a Neurotrophic Factor for the Maintenance of Acetylcholinesterase and Butyrylcholinesterase in the Preganglionically Denervated Superior Cervical Ganglion of the Cat....Pages 47-52
The Application of Immunochemical Techniques to the Study of Cholinergic Function....Pages 53-71
Front Matter....Pages 73-73
The Effect of AH 5183 (2-(4-Phenylpiperidino)-Cyclohexanol) on Acetylcholine Synthesis and Release in the Isolated Guinea Pig Ileum Longitudinal Muscle/Myenteric Plexus Preparation....Pages 75-83
Brain Acetylcholine — A View From the Cerebrospinal Fluid....Pages 85-101
Acetylcholinesterase Activity in Use and Disuse of Muscle....Pages 103-110
Protein Phosphorylation and Phospholipid Metabolism in the Superior Cervical Ganglion....Pages 111-120
AF64A: A Useful Tool in Cholinergic Research....Pages 121-131
A Pharmacological Study of Acetylcholine Synthesis Storage and Release....Pages 133-143
Regulation of Choline Phosphorylation in Rat Striatum....Pages 145-157
The Mechanisms of Action of Norepinephrine and Acetylcholine on the Heart: Role of Protein Phosphorylation....Pages 159-177
Presynaptic Modulation of Cortical Acetylcholine Release: Influence of Age and Adenosine....Pages 179-186
Front Matter....Pages 187-187
The Story of the Renshaw Cell....Pages 189-194
The Blockade of Open Channel of Acetylcholine Receptor is Responsible for Selective Blockade of Nicotinic Transmission....Pages 195-209
Synaptic Mechanisms for Long-Term Potentiation in Sympathetic Ganglia....Pages 211-224
Modulation by Neurotransmitters of the Nicotinic Transmission in the Vertebrates....Pages 225-238
Nicotinic Receptors on Vagal Nerve Terminals in the Atrium....Pages 239-244
Muscarinic Receptor Activation Underlying the Slow Inhibitory Postsynaptic Potential (S-I.P.S.P.) and the Slow Excitatory Postsynaptic Potential (S-E.P.S.P.)....Pages 245-254
Front Matter....Pages 187-187
Alteration of the Ganglionic Fast EPSC by Anticholinesterase Drugs or Protease Treatment....Pages 255-269
Role of Acetylcholine in the Cerebral Cortex....Pages 271-281
Actions of Acetylcholine on Spinal Motoneurons....Pages 283-293
An EEG Investigation of the Ascending Cholinergic Pathways....Pages 295-300
Activation and Blockade of the Nicotinic and Glutamatergic Synapses by Reversible and Irreversible Cholinesterase Inhibitors....Pages 301-328
The Involvement of Alkaline Earth Cations in the Control of Acetylcholine Release....Pages 329-337
Pharmacology of Acetylcholine Activated Ion Channels: Contemporary Approaches....Pages 339-351
Front Matter....Pages 353-353
Receptor-Receptor Interactions in the Modulation of Nicotinic Receptors in Adrenal Medulla....Pages 355-368
Aspects of Cholinergic Function in Amyotrophic Lateral Sclerosis....Pages 369-372
Cholinergic Regulation of REM Sleep: Basic Mechanisms and Clinical Implications for Affective Illness and Narcolepsy....Pages 373-390
Cholinergic Systems in the Central Control of Body Temperature....Pages 391-402
Influence of Frontal Decortication on Drugs Affecting Striatal Cholinergic Activity and Cataleptic Behavior: Restoration Studies....Pages 403-416
Front Matter....Pages 417-417
Succinylcholine — Clinical and Toxicological Aspects....Pages 419-426
Pathology of Experimental Nerve Agent Poisoning....Pages 427-435
Organophosphorus Anticholinesterase-Induced Epileptiform Activity in the Hippocampus....Pages 437-450
Mipafox — Inhibitor of Cholinesterase, Neurotoxic Esterase, and DFP-ase: Is there a “Mipafox-ase”?....Pages 451-458
Addendum....Pages 458-458
Organophosphate Poisoning and its Treatment by Oximes....Pages 459-471
Muscarinic and Nicotinic Mechanisms of Seizures Induced by Cholinesterase Inhibitors: Observations on Diazepam and Midazolam as Antagonists....Pages 473-487
The Effects of 2,5-Hexanedione on Cholinesterase in the Rat....Pages 489-501
Front Matter....Pages 417-417
Electroencephalographic Correlates of Nerve Agent Poisoning....Pages 503-534
Differentiation of Medullary and Neuromuscular Effects of Nerve Agents....Pages 535-550
Actions of Intravenous Eserine and Pyridostigmine on Cat Spinal Cord Renshaw Cells....Pages 551-559
Concluding Remarks: Past, Present and Future of Cholinergic Research....Pages 561-587
Back Matter....Pages 589-595