Neural Development and Regeneration: Cellular and Molecular Aspects

Front Matter....Pages I-XXIII
Front Matter....Pages 1-1
Introduction....Pages 3-3
Developmental Biology of the Optic Nerve....Pages 5-19
Neural Crest Cells Change their Homing Behavior Following Treatment with a Phorbol Ester Drug....Pages 21-30
Differentiation of Glial Precursors in Cerebellar Primary Cultures....Pages 31-41
Neuroectodermal Cells: Storage and Release of Growth Factors....Pages 43-55
Acetyl-L-Carnitine in the Rat’s Hippocampus Aging: Morphological, Endocrine and Behavioral Correlates....Pages 57-66
Glia-Promoting Factors and the Control of Oligodendroglial Growth During Brain Development and Regeneration....Pages 67-79
Cholinergic Neurons of the Rat Forebrain in Slice Cultures; Interactions with Target Tissue and Effects of Nerve Growth Factor....Pages 81-92
Nerve Growth Factor Effects on CNS Cholinergic Neurons In Vivo....Pages 93-103
Expression of NGF Receptors During Development of Central Sensory Pathways in the Rat....Pages 105-114
Rate Limiting Events in Neurite Outgrowth....Pages 115-124
Studies of the Neurotransmitter Plasticity of Cultured Rat Sympathetic Neurons at the Molecular Level....Pages 125-134
Serotonin and Morphogenesis in the Cultured Mouse Embryo....Pages 135-154
Gaba and Taurine as Signals for Neuronal Development and Differentiation....Pages 155-165
Adaptive Changes in an Animal Model of Micro-Encephaly....Pages 167-182
Front Matter....Pages 183-183
Introduction....Pages 185-185
Cell Fate and Gene Expression in the Developing Neural Crest....Pages 187-198
Transiently Induced Sequences as Potential Mediators of Cellular Proliferation and Differentiation....Pages 199-212
Expression of the C-SRC Proto-Oncogene Product in Neural Cells....Pages 213-226
Induction of the 68/72 kDa Heat-Shock Protein during Hydrogen Peroxide Toxicity....Pages 227-231
Front Matter....Pages 183-183
Developmental Expression of Nerve Growth Factor....Pages 233-244
Structure and Expression of ß-Nerve Growth Factor in the Rat Central Nervous System....Pages 245-256
Molecular Aspects of the Rat Nerve Growth Factor Receptor....Pages 257-272
Regulation of the Synthesis of Nerve Growth Factor and Nerve Growth Factor Receptor....Pages 273-283
Regulation of Gene Expression in Nerve Cells: Effect of Growth and Trophic Factors....Pages 285-299
Developmental Aspects of Myelin Membrane Protein Synthesis: Spatial Segregation of Polyribosomes....Pages 301-309
Cytotypic Specialization of the Neuronal Cytoskeleton and the Cytomatrix: Implications for Neuronal Growth and Regeneration....Pages 311-331
A cDNA Coding For Rabbit Neurofilament Protein H: A Window on the Role of H in Neurodegenerative Diseases....Pages 333-341
Structure and Function of Soluble NCAM....Pages 343-352
Front Matter....Pages 353-353
Introduction....Pages 355-355
The Role of Schwann Cells in Peripheral Nervous System Regeneration....Pages 357-366
Regeneration of Somatic Nerves in Permeable and Impermeable Tubes....Pages 367-375
Role of Factors Intrinsic and Extrinsic to CNS Regulating IntraSpinal Degenerative-Atrophy Following Sciatic Nerve Injury....Pages 377-384
Intraspinal Sprouting of Primary Afferents After Spinal Denervation and Treatment with Antibodies to Nerve Growth Factor....Pages 385-398
Role of Nerve Growth Factor in Neuronal Injury and Survival....Pages 399-410
Glial-Derived Substances Associated with CNS Regeneration....Pages 411-428
Neuronal Rescue in Cerebellar Cultures....Pages 429-438
Axonal Regeneration in the Context of Spinal Cord Trauma....Pages 439-450
Neurofilament Processing in Trauma and Disease....Pages 451-468
The Process of Reinnervation of CNS Neurons: Evidence for Local Synthesis of Synaptic Constituents at Postsynaptic Sites....Pages 469-480
Front Matter....Pages 353-353
Ganglioside Treatment of Experimental Brain Injury....Pages 481-489
Effects of Gangliosides and Fibroblast Growth Factor on Central Neurons in Cell Cultures of Rat Hippocampus and Cortex During Development and Regeneration In-Vitro....Pages 491-505
Photochemically Induced Vascular Thrombosis (Photothrombosis): Central Nervous System Consequences and Clinical Possibilities....Pages 507-524
Grafted Fetal Astrocytes Migrate from Host Thoracic Spinal Cord to Lumbar Cord and Medulla....Pages 525-538
Front Matter....Pages 539-539
Introduction....Pages 541-541
The Source and Distribution of Autonomic Nervous System Nerves and Receptors within the Thymus Gland....Pages 543-560
Neuroendocrine Functions in Lymphoid Tissues....Pages 561-570
Interactions Between Thymosins and Neuroendocrine Circuits....Pages 571-582
Nerve Growth Factor and the Immune System....Pages 583-594
Evidence for Lymphoid Cell Participation in Neuroendocrine Pathways....Pages 595-608
Immune System Growth Factor Modulation of Neonatal Oligodendrocyte Growth In Vitro ....Pages 609-619
Front Matter....Pages 621-621
An Investigation of the Role of Phosphatidyl Ionositol Turnover in the Regenerating Rabbit Peripheral Nerve Trunk....Pages 623-624
Effect of EGF on the Labeling of Various RNA Species and of Proteins from Subcellular Fractions in Primary Rat Astroglial Cell Cultures....Pages 625-627
Myelin Treated Macrophages Release Mitogen for Schwann Cells....Pages 629-630
Comparative Structural Features of Nerve Growth Factor and its Receptor....Pages 631-633
Fetal Spinal Cord Homografts Reduce Expected Hind Limb Deficits from Spinal Cervical Fasiculus Gracilis Lesion....Pages 635-636
The Temporal Relation between a Corneal Neuronotrophic Factor and Corneal Nerve Regeneration....Pages 637-638
Slow Axonal Transport in Nerve from Mice with a Genetic Myelin Deficiency (Trembler)....Pages 639-641
Behavioural and Immunological Changes in the Aging Rat....Pages 643-645
Morphological and Biochemical Effects on Striatal Astrocytes after Co-Cultivation with Substantia Nigra Neurons in Primary Cell Culture....Pages 647-649
Front Matter....Pages 621-621
Nerve Growth Factor-Mediated Induction of Choline Acetyltransferase in Fetal and Neonatal Rat Septal Cholinergic Neurons in Organotypic Culture....Pages 651-652
The Developmental Expression of Glial Specific mRNAs in Cultured Rat Brain Cells Identified by in Situ Hybridization....Pages 653-655
Influence of Neurotrophic Factors on the Phosphorylation of Extracellular Proteins....Pages 657-658
Astrocyte Binding of Epidermal Growth Factor....Pages 659-660
Schwann Cells Proliferate in Response to Non-Myelinated Axons....Pages 661-662
Effects of Nerve Growth Factor and Monosialoganglioside GM1 on Forebrain Cholinergic Neurones....Pages 663-664
Modulation of Neurite Growth by Gaba in Cell Culture....Pages 665-666
Effects of an Alpha-2 Adrenergic Receptor Agonist in Spinal Rats....Pages 667-669
Induction of the 68/72 kDa Heat-Stress Protein in Hydrogen Peroxide Toxicity....Pages 671-673
Peripheral Nerve Grafts Implanted into Rat CNS (Optic Nerve) Show Electrophoretic Patterns of Radiolabelled Fast Axonally Transported Proteins Similar to the Pattern seen in the Normal Host CNS Tract....Pages 675-676
Differentiation of a Migratory Bipotential Glial Progenitor Cell in the Developing Rat Optic Nerve....Pages 677-679
Neuronal Primary Cultures - A Characterization....Pages 681-682
Transplants of NGF-rich tissue increases survival and regeneration of axotomized cholinergic neurons in the basal forebrain....Pages 683-685
Neurofilament Processing in Development and Transplantation....Pages 687-688
Antioxidant Enzymatic Activities and Resistance to Oxidative Stress in Primary and Subcultured Rat Astroglial Cells....Pages 689-691
Role of Ascorbate in Laminin Accumulation, Basement Membrane Deposition Acetylcholine Receptor Aggregation on Muscle....Pages 693-694
Back Matter....Pages 695-714