Network Medicine: Complex Systems in Human Disease and Therapeutics

Preface [Joseph Loscalzo, Albert-László Barabási, and Edwin K. Silverman]
1. Scientific Basis of Network Medicine [Edwin K. Silverman and Joseph Loscalzo]
2. Introduction to Network Analysis [Jörg Menche and Albert-László Barabási]
3. Human Interactomes in Network Medicine [Michael E. Cusick, Benoit Charloteaux, Thomas Rolland, Michael A. Calderwood, David E. Hill, and Marc Vidal]
4. Social Networks in Human Disease [Douglas A. Luke and Martin W. Schoen]
5. Phenotype, Pathophenotype and Endo(patho)phenotype in Network Medicine [Calum A. MacRae]
6. A New Paradigm for Defining Human Disease and Therapy [Joseph Loscalzo]
7. Complex Disease Genetics and Network Medicine [Edwin K. Silverman]
8. Transcriptomics and Network Medicine [John Quackenbush and Kimberly Glass]
9. Post-translational Modifications of the Proteome: The Example of Tau in the Neuron and the Brain [Guy Lippens, Jeremy Gunawardena, Isabelle Landrieu, Caroline Smet-Nocca, Sudhakaran Prabakaran, Benjamin Parent, Arnaud Leroy, and Isabelle Huvent]
10. Epigenetics and Network Medicine [Dawn L. DeMeo and Scott T. Weiss]
11. Metabolomics and Network Medicine [Jessica Lasky-Su and Clary B. Clish]
12. Using Integrative -omics Approaches in Network Medicine [Shuyi Ma, John C. Earls, James A. Eddy, and Nathan D. Price]
13. Cancer Network Medicine [Takeshi Hase, Samik Ghosh, Sucheendra K. Palaniappan, and Hiroaki Kitano]
14. Systems Pharmacology in Network Medicine [Edwin K. Silverman and Joseph Loscalzo]
15. Systems Approaches to Clinical Trials [Elliott M. Antman]
16. Microbiomics in Network Medicine [Joanne E. Sordillo, George M. Weinstock, and Augusto A. Litonjua]
Abbreviations
Glossary
Contributors
Index