Neoplastic diseases of the blood

Front......Page 1
Contents......Page 9
Contributors......Page 13
Preface......Page 19
SECTION ONE - Chronic Leukemias and Related Disorders......Page 21
1: A History of the Chronic Leukemias......Page 23
2: Epidemiology of the Chronic Leukemias......Page 29
3: Pathology and Morphology of Chronic Leukemias and Related Disorders......Page 36
4: Molecular Biology and Cytogenetics of Chronic Myeloid Leukemia......Page 56
5: Diagnosis and Treatment of Chronic Myeloid Leukemia......Page 73
6: Molecular Biology and Cytogenetics of Chronic Lymphocytic Leukemia......Page 90
7: Diagnosis and Treatment of Chronic Lymphocytic Leukemia......Page 103
8: Diagnosis and Treatment of Hairy Cell Leukemia......Page 116
9: The Pathogenesis, Diagnosis, and Treatment of Polycythemia Vera......Page 131
10: The Diagnosis and Treatment of Essential Thrombocythemia and Chronic Idiopathic Myelofibrosis......Page 145
SECTION TWO - Acute Leukemias......Page 153
11: Historical Perspectives on Acute Leukemias......Page 155
12: Human T-Cell Lymphoma/Leukemia Virus – Associated T-Cell Lymphoma and Leukemia......Page 161
13: Epidemiology and Hereditary Aspects of Acute Leukemia......Page 184
14: Classification of the Acute Leukemias: Cytochemical and Morphological Considerations......Page 196
15: Immunobiology of Acute Leukemia......Page 214
16: Cytogenetics of Acute Leukemia......Page 252
17: Diagnosis and Treatment of Childhood Acute Lymphoblastic Leukemia......Page 269
18: Diagnosis and Treatment of Adult Acute Lymphoblastic Leukemia......Page 293
19: Diagnosis and Treatment of Childhood Acute Myelogenous Leukemia......Page 326
20: Diagnosis and Treatment of Adult Acute Myeloid Leukemia Other Than Acute Promyelocytic Leukemia......Page 336
21: Acute Promyelocytic Leukemia......Page 356
22: Therapy-Related Acute Myelogenous Leukemia......Page 390
23: Myelodysplastic Syndromes......Page 415
SECTION THREE - Myeloma and Related Disorders......Page 433
24: History of Multiple Myeloma......Page 435
25: Cytokines and Signal Transduction in Multiple Myeloma......Page 444
26: Epidemiology of Multiple Myeloma......Page 454
27: Immunoglobulins and Laboratory Recognition of Monoclonal Proteins......Page 466
28: Cytogenetic Abnormalities in the Monoclonal Gammopathies......Page 490
29: Molecular Genetics in Multiple Myeloma and Related Disorders......Page 497
30: Staging, Kinetics, and Prognosis in Multiple Myeloma......Page 508
31: Diagnosis and Treatment of Multiple Myeloma......Page 547
32: Syndromes and Special Presentations Associated with Plasma Cell Myeloma......Page 567
33: Waldenström’s Macroglobulinemia......Page 582
34: Heavy-Chain Disease......Page 593
35: Amyloidosis (AL)......Page 615
36: Monoclonal Gammopathies of Undetermined Significance......Page 639
SECTION FOUR - Lymphoma......Page 669
37: Historical Overview of Malignant Lymphoma......Page 671
38: Genetic Factors in Lymphomagenesis......Page 682
39: Epidemiology and Hereditary Aspects of Malignant Lymphoma and Hodgkin’s Disease......Page 693
40: Pathology of Non-Hodgkin’s Lymphomas and Hodgkin’s Disease......Page 707
41: Immunology of the Lymphomas......Page 754
42: Cytogenetics of Non-Hodgkin’s Lymphoma and Hodgkin’s Disease......Page 786
43: Diagnosis and Treatment of Hodgkin’s Disease......Page 816
44: Radiotherapeutic Management of Lymphomas......Page 838
45: Diagnosis and Treatment of Non-Hodgkin’s Lymphoma of Adults......Page 847
46: Non-Hodgkin’s Lymphoma of Childhood......Page 863
47: Lymphoma in Other Diseases......Page 882
SECTION FIVE - Supportive Care......Page 939
48: Historical Perspectives in Supportive Care......Page 941
49: Prevention of Infections in Patients With Hematological Malignancies......Page 946
50: Evaluation and Management of Bacterial and Fungal Infections Occurring in Patients With a Hematological Malignancy......Page 975
51: Viral Infections in Patients with Hematological Malignancies......Page 988
52: Therapeutic Cytapheresis and Plasma Exchange......Page 1026
53: Red Cell Transfusions in Patients with Hematologic Malignancies......Page 1037
54: Platelet and Granulocyte Transfusion......Page 1048
55: Stem Cell Processing and Purging......Page 1069
56: Alternative Sources of Hematopoietic Stem Cells and Their Clinical Applications......Page 1084
57: Umbilical Cord Blood Banking and Transplantation......Page 1099
58: HLA Typing in Hematopoietic Cell Transplantation......Page 1105
59: Special Care of Blood and Marrow Stem Cell Transplant Patients......Page 1116
60: Hematopoietic Growth Factors in the Supportive Care and Treatment of Patients with Hematologic Malignancies......Page 1143
61: Bleeding and Thrombosis in Hematologic Neoplasia......Page 1157
62: Psychological Aspects of Hematological Malignancies......Page 1175
Index......Page 1187