Mucus in Health and Disease—II

Front Matter....Pages i-xv
Front Matter....Pages 1-1
Biosynthesis of Mucus Glycoproteins....Pages 3-28
Antigenicities of Mucins - Their Relevance to Tumour Associated and Stage Specific Embryonic Antigens....Pages 29-37
Structural and Antigenic Diversity in Mucin Carbohydrate Chains....Pages 39-41
The Use of Radioimmunoassay as a Probe of the Antigenic Determinants and Structure of Human Small Intestinal Mucin....Pages 43-47
Trisaccharides from Blood Group A 1 And A 2 Mucous Glycoproteins....Pages 49-51
Structure and Function of Mucus....Pages 53-74
Modification of the Rheological Properties of Mucus by Drugs....Pages 75-84
A Rheological Study of Mucus - Antibiotic Interactions....Pages 85-88
Biopolymer Induced Changes in Mucus Viscoelasticity....Pages 89-92
Evaluation of Mucolytic Activity Using a Purified Mucus Glycoprotein Gel....Pages 93-95
Rheological Studies on Native Pig Gastric Mucus Gel....Pages 97-99
Mucus Hydration: A Donnan Equilibrium Controlled Process....Pages 101-103
Dissolution of Tetracycline Hydrochloride in Mucin Solutions....Pages 105-108
The Use of High Resolution Carbon-13 NMR in the Study of Mucus....Pages 109-111
Front Matter....Pages 113-113
The Structure and Physiology of Gastrointestinal Mucus....Pages 115-133
Studies Upon the Secretion of Gastric Mucus from Normal Subjects....Pages 135-136
The Neutral Carbohydrate Chains of Gastric and Duodenal Mucosubstances....Pages 137-139
The Composition of a Macromolecular Extract of Combined Human Body and Fundic Mucosa....Pages 141-143
Differences in Mucus Glycoproteins of Small Intestine from Subjects With and Without Cystic Fibrosis....Pages 145-146
Gastric Mucosubstances and Benign Gastric Ulceration....Pages 147-149
Front Matter....Pages 113-113
Reduction by Mercaptoethanol and Proteolysis of the Non-Glycosylated Peptide Region of Pig Gastric Mucus Glycoprotein....Pages 151-153
An Insoluble Mucin Complex from Rat Small Intestine....Pages 155-157
Composition and Structure of Rat Brunner’s Glands and Gastric Mucous Glycoprotein....Pages 159-161
Effect of Lysolecithin on the Constituents of Gastric Mucus....Pages 163-174
Synthesis and Secretion of Glycoproteins by Isolated Rat Small Intestinal Epithelial Cells....Pages 175-177
Ultracentrifugation of Salivary Mucins....Pages 179-181
Studies of the Protective Properties of Gastric Mucus....Pages 183-185
Studies of the pH Gradient Across the Mucus on Rat Gastric Mucosa in Vivo and Across Mucus on Human Gastric Mucosa In Vitro....Pages 187-188
Restriction of Hydrogen and Sodium Ion Diffusion in Porcine Gastric Mucin: A Concentration Dependent Phenomenon....Pages 189-191
Mucus and Gastric Acid-Bicarbonate Interaction....Pages 193-195
Clinical Aspects of Gastrointestinal Mucus....Pages 197-198
Ultrastructural Alterations in the Colonic Mucus Layer During Carcinogenesis : A Scanning Electron Microscopy Study....Pages 199-224
Gallbladder Mucin Glycoprotein Hypersecretion in Experimental Cholelithiasis: Role of Mucin Gel in Nucleation of Cholesterol Gallstones....Pages 225-229
Gastric Mucus Degradation In Vivo in Peptic Ulcer Patients and the Effects of Vagotomy....Pages 231-234
Histochemical Changes in Mucus in Duodenal Ulceration....Pages 235-237
Protection Against Nematodes by Intestinal Mucus....Pages 239-241
The Intestinal Mucus Barrier to Parasites and Bacteria....Pages 243-245
Front Matter....Pages 247-248
Structure and Function of Cervical Mucus....Pages 249-249
Control of Human Cervical Mucin Glycosylation by Endogenous Fucosyl and Sialyltransferases....Pages 251-263
Front Matter....Pages 265-267
Cyclic Changes in Glycoprotein Synthesis and Secretion by the Human Endocervix....Pages 249-249
Carbohydrate Chains of Human Pre- and Postovulatory Cervical Mucous Glycoprotein....Pages 269-270
Isolation and Purification of the Mucin Component of Human Cervical Mucus....Pages 271-272
Speed-Dependent Sedimentation-Velocity of Human Cervical Mucins in the Analytical Ultracentrifuge....Pages 273-275
Endocervical Changes in the Guinea Pig after Treatment With 11-ß - Oestradiol and 9,10 Dimethylbenzanthracene....Pages 277-279
Histochemical Alterations in the Uterine Endocervical Mucosa in Different Phases of the Normal Menstrual Cycle and in the Altered Cycle....Pages 281-284
A Preliminary Report on the Intracervical Contraceptive Device - Its Effect on Cervical Mucus....Pages 285-287
A Scanning Electron Microscopic Study of Human Cervical Mucus....Pages 289-291
A Freezing Artefact Associated with the Preparation of Mucin for Examination Using the Scanning Electron Microscope....Pages 293-296
Cervical Mucus: Its Physiological Role And Clinical Significance....Pages 297-300
The Mechanisms and Analysis of Sperm Migration Through Cervical Mucus....Pages 301-318
Spermatozoal Velocity in Human Cervical Mucus Measured by Laser Doppler Velocimetry....Pages 319-330
Front Matter....Pages 331-332
Respiratory Mucus: Structure, Metabolism and Control of Secretion....Pages 333-333
Characteristics of Human Bronchial Mucus Glycoproteins Prepared in the Absence of Reducing Agents....Pages 335-350
Isolation and Characterisation of Neutral Oligosaccharides from Human Bronchial Glycoproteins....Pages 351-352
Macromolecular Composition of Secretions Produced by Human Bronchial Explants....Pages 353-355
Characterisation of Sol and Gel Phases of Infected and Mucoid Sputum Samples from a Chronic Bronchitic Patient....Pages 357-360
The Effects of Low Molecular Weight Mucus Modifying Substances on the Appearance of Mucin Gels in the Scanning Electron Microscope....Pages 361-364
Clinical Aspects of Respiratory Mucus....Pages 365-368
Chemical Composition of Pathological Human Tracheobronchial Mucus Collected by Fiberoptic Bronchoscopy....Pages 369-391
Front Matter....Pages 393-395
Spinability and transport properties of sputum in chronic bronchitis....Pages 333-333
The Mechanisms and Control of Bronchial Mucous Cell Hyperplasia....Pages 397-398
The Role of Mucociliary Transport in the Pathogenesis of Chronic Obstructive Pulmonary Disease....Pages 399-409
Regional Variations of Mucus Clearance in Normal and in Bronchitic Mammalian Airways....Pages 411-415
The Development of an In Vivo Model for the Evaluation of Drugs Affecting Tracheal Mucus....Pages 417-418
Effect of S-Carboxymethylcysteine on the Biophysical and Biochemical Properties of Mucus in Chronic Bronchitics....Pages 419-421
Stimulation of Nasal Mucus Secretion in the Rabbit....Pages 423-429
Back Matter....Pages 431-432
....Pages 433-441