Mononuclear Phagocytes: Functional Aspects

Front Matter....Pages I-XXXIX
Cells of the Mononuclear Phagocyte System....Pages 1-40
Front Matter....Pages 41-41
Peroxidase and Catalase in Monocytes, Macrophages, Epithelioid Cells and Giant Cells of the Rat....Pages 43-60
Changes in Peroxidase Distribution within Organelles of Blood Monocytes and Peritoneal Macrophages after Surface Adherence in Vitro and in Vivo....Pages 61-86
Development of Exudate-Resident Macrophages, on the Basis of the Pattern of Peroxidatic Activity in Vivo and in Vitro....Pages 87-118
The Vacuolar Apparatus of Alveolar Macrophages and the Turnover of Surfactant....Pages 119-155
Properties of Kupffer Cells....Pages 157-202
Origin and Structure of the Osteoclast....Pages 203-233
Veiled Cells Resembling Langerhans Cells....Pages 235-275
Front Matter....Pages 277-277
Characteristics, Origin and Kinetics of Human and Murine Mononuclear Phagocytes....Pages 279-298
The Origin and Properties of Peripheral Lymph Mononuclear Phagocytes....Pages 299-324
Humoral Control of Monocyte Production During Inflammation....Pages 325-341
Long-Term Cultures of Murine Bone Marrow Mononuclear Phagocytes....Pages 343-361
Effector Cell Functions in Long-Term Culture of Murine, Prosimian, and Human Bone Marrow....Pages 363-376
Formation of Colonies by Mononuclear Phagocytes Outside the Bone Marrow....Pages 377-416
Regulation of Macrophage Production by a Colony-Stimulating Factor....Pages 417-437
Functions of Macrophage Cell Lines....Pages 439-457
Front Matter....Pages 459-459
Gradients of Chemotactic Factors in Various Assay Systems....Pages 461-473
The Locomotor Behaviour of Human Blood Monocytes in Chemotactic and Chemokinetic Environments and the Role of Substratum in Monocyte Locomotion....Pages 475-504
Alteration of Macrophage and Monocyte Membrane Potential by Chemotactic Factors....Pages 505-526
MIF/MAF-Macrophage Interactions: Biochemical Characterization of a Putative Glycolipid Receptor for MIF and the Existence and Properties of Two Distinct MIFs....Pages 527-537
Front Matter....Pages 459-459
Lymphokine-Induced Modulation of Macrophage Functions....Pages 539-567
An Inhibitor of Macrophage Accumulation Produced by Neoplasms: Its Role in Abrogating Host Resistance to Cancer....Pages 569-592
Front Matter....Pages 593-593
Membrane Flow During Endocytosis....Pages 595-612
Membrane Recycling (Shuttle?) in Endocytosis....Pages 613-647
The Iodination and Turnover of Macrophage Plasma Membrane Polypeptides....Pages 649-664
Macrophage Ecto-Enzymes: Their Identification, Metabolism, and Control....Pages 665-683
Membrane Lipids and the Control of Endocytosis....Pages 685-703
Surface Functions in Dividing Macrophages....Pages 705-732
Front Matter....Pages 733-733
Fc Receptors on Mouse Macrophages....Pages 735-756
Structural Characteristics of Fc Receptors on Macrophages....Pages 757-781
Quantitative Studies on the Interaction of Macrophages with Antibody and Immune Complexes....Pages 783-808
Hormone Receptors and Hormonal Regulation of Macrophage Physiological Functions....Pages 809-835
In Vivo and in Vitro Evidence for a Lysosomal Enzyme Uptake System in Macrophages....Pages 837-864
Cellular Recognition by Phagocytes: Role of Lectin-Like Receptor(s)....Pages 865-884
Front Matter....Pages 893-893
Phagocytosis....Pages 895-919
Modulation of Macrophage Plasma Membrane Receptors for IgG and Complement....Pages 921-940
Genetic and Functional Studies of Continuous Macrophage-Like Cell Lines....Pages 941-970
Contractile Proteins and the Mechanism of Phagocytosis in Macrophages....Pages 971-998
Factors Modifying the Fusion of Phagosomes and Lysosomes: Art, Fact, and Artefact....Pages 999-1038
Manipulations of Phagosome-Lysosome Fusion in Cultured Macrophages: Potentialities and Limitations....Pages 1039-1055
Front Matter....Pages 893-893
Cyclic Nucleotides and Phagosome-Lysosome Fusion in Mouse Peritoneal Macrophages....Pages 1057-1075
Determinants of Phagosome-Lysosome Fusion in Mouse Macrophages....Pages 1077-1102
Front Matter....Pages 1103-1103
Oxygen Intermediates and the Microbicidal Event....Pages 1105-1141
Release of Superoxide Anion by Macrophages: Effect of in Vivo or in Vitro Priming....Pages 1143-1163
The Release of Hydrogen Peroxide from Mononuclear Phagocytes and its Role in Extracellular Cytolysis....Pages 1165-1186
Oxidative Metabolism of Mononuclear Phagocytes....Pages 1187-1217
The Oxygen Metabolism of Human Blood Monocytes and Neutrophils....Pages 1219-1245
Effects of Oxygen on Metabolic Patterns and Endocytosis of Macrophages....Pages 1247-1269
Front Matter....Pages 1271-1271
Lysozyme and Plasminogen Activator: Constitutive and Induced Secretory Products of Mononuclear Phagocytes....Pages 1273-1298
Modulation of Macrophage Plasminogen Activator Secretion....Pages 1299-1316
The Synthesis of Arachidonic Acid Oxygenation Products by Various Mononuclear Phagocyte Populations....Pages 1317-1350
Generation of Tissue Thromboplastin by Human Monocytes....Pages 1351-1367
Secretion of Lysosomal Enzymes by Macrophages....Pages 1369-1384
Synthesis and Release of Complement Components by Macrophages....Pages 1385-1417
Front Matter....Pages 1419-1419
The Stimulation of Mononuclear Phagocytes by Components of the Classical and the Alternative Pathways of Complement Activation....Pages 1421-1442
Complement, Coagulation and Mononuclear Phagocytes....Pages 1443-1466
Extracellular Stimulation of Intracellular Killing....Pages 1467-1494
Respiratory Pathways of Macrophages — Cellular Localization and Relation to Cidal Activity....Pages 1495-1514
Macrophage Activation by Interferon or Interferon Inducers....Pages 1515-1538
Macrophage Activation by IgE....Pages 1539-1558
Front Matter....Pages 1419-1419
The Effect of Complement on the Degradation of Soluble Immune Aggregates by Kupffer Cells and Peritoneal Macrophages in Vitro....Pages 1559-1578
Macrophage Activation in Vitro by Phagocytosis....Pages 1579-1584
Front Matter....Pages 1585-1585
Induction of Macrophage Microbicidal Activity....Pages 1587-1610
Interactions of Macrophages with Intravacuolar Bacteria and Protozoa....Pages 1611-1629
Cytotoxic and Microbicidal Properties of Macrophages....Pages 1631-1653
Significance of Systemic Macrophage Activation in Response to Tumor Growth....Pages 1655-1679
Regulation of Macrophage Non-Specific Tumoricidal Capability....Pages 1681-1724
Distinctive Characteristics of Host Tumor Resistance in a Rat Fibrosarcoma Model System....Pages 1725-1742
Intracellular Killing, Degradation, Metabolic Activity, and Increase in β-Galactosidase Activity as Markers for Activated Macrophages....Pages 1743-1759
Cytotoxicity of Human Monocytes Against Sensitized Erythrocytes....Pages 1761-1777
Front Matter....Pages 1779-1779
Dendritic Cells and Macrophages — Current Knowledge of Their Distinctive Properties and Functions....Pages 1781-1807
Reticulum Cells and Macrophages in the Immune Response....Pages 1809-1836
Multiple Interactions Between Listeria-Immune T Lymphocytes and Macrophages: Regulation by the Major Histocompatibility Gene Complex....Pages 1837-1856
Role of Macrophages in the in Vitro Induction and Regulation of Antibody Responses....Pages 1857-1885
Physical and Functional Macrophage-Lymphocyte Interactions in Antigen Recognition by T Lymphocytes....Pages 1887-1908
Expression of Ir Genes and Ia Antigens by Adherent Accessory Cells Required for Antigen-Specific Antibody-Forming Cell Responses....Pages 1909-1924
Summation....Pages 1925-1929
Back Matter....Pages 1931-1938