Mononuclear Phagocytes: Biology of Monocytes and Macrophages

Front Matter....Pages i-xx
Front Matter....Pages 1-1
Production and migration of monocytes and kinetics of macrophages....Pages 3-12
The biology and action of colony stimulating factor-1....Pages 13-20
The contribution and limitations of CR3-dependent recruitment of macrophages to inflammatory and lymphoid sites....Pages 21-30
Lymphocyte-monocyte locomotor interactions and clustering....Pages 31-36
Macrophage-microglia responses to excitotoxin-induced degeneration in the central nervous system....Pages 37-44
The role of macrophages in different stages of experimental allergic encephalomyelitis in Lewis rats....Pages 45-49
Hemopoiesis during infection in mice: an inducible, genetically controlled response mediated by CD4 + T cells homing in their bone marrow....Pages 50-54
Cellular interactions between stromal macrophages and haematopoietic cells....Pages 55-69
The role of intestinal dendritic cells in antigen presentation....Pages 70-74
Migration and maturation of non-lymphoid dendritic cells....Pages 75-80
Front Matter....Pages 81-81
Endothelial-dependent mechanisms of monocyte adhesion....Pages 83-91
Adhesion molecules of human monocytes....Pages 92-104
Human monocytes exhibit different mechanisms of adhesion to nonstimulated or Cytokine-stimulated human endothelial cells....Pages 105-116
Activation of LFA-1, and its role in mediating adhesion of monocytes and lymphocytes to endothelium....Pages 117-122
Monocyte adhesion to rIL-4-stimulated human endothelial....Pages 123-128
The importance of leukocyte integrin activation in myeloid cell interaction with endothelium....Pages 129-133
Mechanisms of monocyte adhesion to activated human endothelium in vitro....Pages 134-137
PECAM-1: an adhesion molecule at the junctions of endothelial cells....Pages 138-148
Involvement of ELAM-1 in monocyte adherence to and migration across IL-1-stimulated endothelial cell monolayers....Pages 149-154
Localized expression of a mononuclear leukocyte adhesion molecule by vascular endothelium during atherogenesis....Pages 155-160
Front Matter....Pages 81-81
Endothelial cell activation and mononuclear cell infiltration during allergic and irritant contact dermatitis....Pages 161-166
Front Matter....Pages 167-167
Fc receptor function in macrophages and lymphocytes....Pages 169-176
Polymorphism and functioning of a low-affinity IgG Fc receptor, hFcγRII (CD32)....Pages 177-182
Regulation of leukocyte integrins....Pages 183-187
Membrane surface antigen expression on human monocytes: changes during purification, in vitro activation and transmigration across monolayers of endothelial cells....Pages 188-192
Monocyte/macrophage receptors for proteins modified by advanced glycation end products: role in normal tissue remodeling and in pathology....Pages 193-201
Modulation of endothelial function and endothelial-monocyte interaction by advanced glycosylated end products of proteins....Pages 202-207
The mannose receptor and phagocytosis....Pages 208-213
Receptor-mediated endocytosis and phagocytosis share common determinants for intracellular traficking....Pages 214-223
Carbohydrate recognition receptors of the macrophage and their regulation....Pages 224-232
The regulation of urokinase plasminogen activator gene expression in macrophages....Pages 233-240
Front Matter....Pages 241-241
Generation of reactive oxygen species by phagocytes....Pages 243-253
Immune therapy and potential for gene therapy in chronic granulomatous disease of childhood....Pages 254-258
Antimicrobial mechanisms of macrophages....Pages 259-267
Defensins in macrophages....Pages 268-272
Antimicrobial polypeptides in mouse macrophages....Pages 273-278
Synthesis of nitric oxide from L-arginine: a cytokine inducible pathway with antimicrobial activity....Pages 279-292
Killer and target: a tale of two cells....Pages 293-302
Stimulation of interleukin-1β release from human monocytes by the action of pore-forming bacterial toxins....Pages 303-307
Ingestion of pulmonary surfactant by human monocytes inhibits their antibacterial functions....Pages 308-314
Front Matter....Pages 241-241
Biochemical basis for the candidacidal mechanisms of human mononuclear phagocytes....Pages 315-320
Front Matter....Pages 321-321
Effects of interleukin-1 and related cytokines on host defense against infections....Pages 323-327
Functional activity of IL-4 cultured human peripheral blood monocytes....Pages 328-332
Interleukin-6: its role in the cytokine network....Pages 333-339
Interleukin-8: a chemotactic cytokine produced by macrophages and tissue cells....Pages 340-345
Tumor necrosis factor. Induction and biological effects in humans....Pages 346-354
LPS reactivity of monocytes and TNF gene polymorphism....Pages 355-358
Soluble and cell surface receptors for tumor necrosis factor....Pages 359-365
Cytokine gene expression in situ: differential expression of lysozyme, IL-1, and TNF mRNA in murine liver during BCG infection....Pages 366-374
Anti-cytokines....Pages 375-380
Regulation of macrophage functions by macrophage deactivating factor, a tumor cell-derived cytokine....Pages 381-388
Properties and binding characteristics of monocyte chemotactic and activating factor (MCAF)....Pages 389-396
Lysozyme gene expression in macrophages and specialized epithelial cells....Pages 397-403
The role of macrophage-derived growth factors in tissue repair....Pages 404-409
Front Matter....Pages 411-411
Chemoattractant stimulus-response coupling....Pages 413-424
Molecular bases of macrophage activation: regulation of class II MHC genes in tissue macrophages....Pages 425-436
Signal transduction in resident and activated macrophages....Pages 437-450
Myristoylated protein kinase C substrates and intracellular signaling pathways in macrophages....Pages 451-462
Regulation of IFNγ/IL-2 induced macrophage gene expression....Pages 463-467
Understanding how macrophages recognize bacterial lipopolysaccharide....Pages 468-471
Front Matter....Pages 411-411
Participation of the cytoskeleton in macrophage responses to LPS....Pages 472-477
Cytoskeletal changes during Fc receptor-mediated phagocytosis....Pages 478-482
The role of calcium and protein kinase C in the intracellular killing of bacteria by human monocytes....Pages 483-488
ATP-induced pores and gap junctions in macrophages....Pages 489-493
Macrosialin, a macrophage endosomal sialoprotein differentially glycosylated in response to inflammatory stimuli....Pages 494-499
Intracellular protein tyrosine kinases of the src family in mononuclear phagocytes....Pages 500-507
Front Matter....Pages 509-509
The role of interferon-γ in inflammation....Pages 511-516
Activation of macrophage antimicrobial activities: complex interactions of cytokines for induction of resistance to infection and intracellular destruction of pathogens....Pages 517-522
Priming/activation of macrophages for antileishmanial activity: role of TNF-α and nitric oxide in killing of Leishmania donovani....Pages 523-527
Towards an understanding of the molecular basis for Legionella pneumophila pathogenesis....Pages 528-533
Intracellular killing of Candida albicans by activated peritoneal macrophages....Pages 534-539
Cytokine and viral gene expression during infection of monocytes by the human immunodeficiency virus: central role of interferons in the promotion and resolution of virus infection....Pages 540-549
Uptake of antibiotics by monocytes and macrophages....Pages 550-553
Transport of organic anions and antibiotics in macrophages....Pages 554-558
Front Matter....Pages 559-559
The initiation of cell-mediated immune responses....Pages 561-571
Epidermal Langerhans cells in cell-mediated immunity....Pages 572-576
T cell-phagocyte interactions induced by Listeria monocytogenes....Pages 577-584
Cytokines produced by T cell subset-depleted naive and listeria-immune spleen cells....Pages 585-592
Pathogenesis of Listeria monocytogenes....Pages 593-601
Macrophage activation by recombinant cytokines....Pages 602-617
Front Matter....Pages 559-559
Effect of interferon-γ on the development of inflammatory lesions in the liver of mice during infection with Listeria monocytogenes....Pages 618-625
The role of TNF in listeriosis....Pages 626-630
Monokines in cell-mediated immunity to bacterial infections....Pages 631-635
Control of mycobacterial infection by interleukin-activated macrophages....Pages 636-643
Leprosy a model for cell mediated immunity: the effects and consequences of recombinant lymphokine immunotherapy....Pages 644-648
Cell-mediated immunity to mycobacteria: the effect of cytolysis on parasite viability....Pages 649-650
Activation of murine peritoneal macrophages by the mycobacterial 65 kD heat-shock protein....Pages 651-656
Interaction between activated macrophages and Mycobacterium fortuitum....Pages 657-664
Back Matter....Pages 665-668