Molecular Mechanisms of Dementia: Biomarkers, Neurochemistry, and Therapy

Cover
Molecular Mechanisms of Dementia: Biomarkers, Neurochemistry,
and Therapy
Copyright
Dedication
About the Author
Preface
Acknowledgments
List of Abbreviations
1 Neurochemical Aspects of Dementia
	Introduction
	Classification of Dementias
	Risk Factors for Dementias
	Symptoms of Dementias
	Etiology of Dementias
	Biomarkers for Dementias
	Animal Models for Dementias
	Autophagy and Dementias
	Link Between Dementias and Cognitive Dysfunction
	Lifestyle, Cognitive Function, and Dementias
	Dementia-Linked Chronic Visceral and Neurological Disorders
	Effects of Diet and Exercise on Dementia
	Websites for More Information on Dementia
	Conclusion
	References
	Further Reading
2 Neurochemical Aspects of Poststroke Dementia
	Introduction
	Risk Factors for Poststroke Dementia
	Biomarkers for Poststroke Dementia
	Cellular and Neurochemical Changes in Poststroke Dementia
	Oxidative Stress-Mediated Injury in Poststroke Dementia
	Neuroinflammation in Poststroke Dementia
	Immune Responses in Poststroke Dementia
	Poststroke Dementia and Cognitive Dysfunction
	Conclusion
	References
	Further Reading
3 Neurochemical Aspects of Alzheimer’s Type of Dementia
	Introduction
	Risk Factors for Alzheimer Type of Dementia
	Biomarkers for Alzheimer’s Type of Dementia
	Neurochemical Changes in Alzheimer’s Type of Dementia
	Oxidative Stress in Alzheimer’s Type of Dementia
	Neuroinflammation in Alzheimer’s Type of Dementia
	Immune Responses in Alzheimer’s Type of Dementia
	Cognitive Dysfunction in Alzheimer’s Type of Dementia
	Conclusion
	References
	Further Reading
4 Neurochemical Aspects of Lewy Body Dementia
	Introduction
	α-Synuclein and LBD Spectrum Disorders
	Risk Factors for Lewy Body Dementia, Parkinson’s Disease, and PDD
	Diagnosis and Biomarkers for Lewy Body Dementia, Parkinson’s Disease, and PDD
	Neurochemical Changes in Lewy Body Dementia, Parkinson’s Disease, and PDD
	Animal Models for Parkinson’s Disease
	Oxidative Stress in Lewy Body Dementia, Parkinson’s Disease, and PDD
	Neuroinflammation in Lewy Body Dementia, Parkinson’s Disease, and PDD
	Immune Responses in Lewy Body Dementia, Parkinson’s Disease, and PDD
	Cognitive Dysfunction in Lewy Body Dementia, Parkinson’s Disease, and PDD
	Conclusion
	References
	Further Reading
5 Neurochemical Aspects of Vascular Dementia
	Introduction
	Small Vessel Disease and Vascular Dementia
	Risk Factors for Vascular Dementia
	Diagnosis of Vascular Dementia
	Biochemical and Neuropathological Changes in Vascular Dementia
	Oxidative Stress in Vascular Dementia
	Neuroinflammation in Vascular Dementia
	Animal Models for Vascular Dementia
	Immune Responses in Vascular Dementia
	Vascular Dementia and Cognitive Dysfunction
	Conclusion
	References
	Further Reading
6 Neurochemical Aspects of Frontotemporal Dementia
	Introduction
	Diagnosis of Frontotemporal Dementia
	Commonalities Between Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
	Diagnosis of Frontotemporal Dementia
	Biomarkers for Frontotemporal Dementia
	Risk Factors for Frontotemporal Dementia
	Neurochemical Changes in Frontotemporal Dementia
	Oxidative Stress in Frontotemporal Dementia
	Neuroinflammation in Frontotemporal Dementia
	Immune Responses in Frontotemporal Dementia
	Frontotemporal Dementia and Cognitive Dysfunction
	Conclusion
	References
	Further Reading
7 Potential Treatment Strategies for Dementia With Pharmacological and Nonpharmacological Interventions
	Introduction
	Cholinergic Strategies for the Treatment of Dementia
	Memantine for the Treatment of Alzheimer’s Disease and Alzheimer’s Disease Type of Dementia
	Nonpharmacological Treatment of Dementia
	Treatment of Dementia With Aromatherapy
	Treatment of Dementia With Acupuncture
	Treatment of Dementia With Music
	Effects of Exercise on Dementia
	Treatment of Dementia With Transcranial Magnetic Stimulation
	Treatment of Dementia With Meditation
	Conclusion
	References
	Further Reading
8 Potential Treatment Strategies for the Treatment of Dementia With Chinese Medicinal Plants
	Introduction
	Huperzine A and Dementia
	Ginkgo biloba and Dementia
	Ginseng and Dementia
	Anemarrhena Rhizome (Rhizoma Anemarrhenae) and Dementia
	Green Tea and Dementia
	Integripetal Rhodiola Herb and Dementia
	Danshen Root and Dementia
	Radix Puerariae (Kudzu Root) and Dementia
	Chinese Formulations and Dementia
	Conclusion
	References
	Further Reading
9 Potential Treatment Strategies of Dementia With Ayurvedic Medicines
	Introduction
	Indian Medicinal Plants for the Treatment of Dementia
	Withania somnifera and Dementia
	Curcumin and Dementia
	Brahmi (Bacopa monnieri) and Dementia
	Shankpushpi and Dementia
	Gotu Kola and Dementia
	Guggulu and Dementia
	Rhodiola rosea and Dementia
	Tulsi and Dementia
	Jyotishmati and Dementia
	Nardostachys jatamansi and Dementia
	Conclusion
	References
	Further Reading
10 Summary and Perspective for Future Research on Dementia
	Introduction
	Epidemiology of Dementia
	Interventions to Delay the Onset of Dementia
	Conclusion
	References
	Further Reading
Index