Molecular Evolution on Rugged Landscapes : Protein, RNA, and the Immune System (Volume IX)

Content: Rugged Landscapes and Evolution * Optimization on Rugged Landscapes Richard Palmer   * A Spin-Glass Model of Evolution C. Amitrano, L. Peliti, and M. Saber   * What Can Physics Do For Biology? D. L. Stein   * Optimization of RNA Structure and Properties P. Schuster    Somatic Evolution of Antibody Variable-Region Genes & Maturation of the Immune Response * Affinity Maturation: A Retrospective View Herman N. Eisen   * Maturation through Hypermutation and Selection C. Berek and M. Apel   * Affinity Maturation on Rugged Landscapes Catherine Macken and Alan S. Perelson   * Maturation of the Humoral Immune Response: A Neo-Darwinian Process? Tim Manser   * The NK Model of Rugged Fitness Landscapes and Its Application to Maturation of the Immune Response Stuart A. Kauffman and Edward D. Weinberger   * Use of Antibodies as Molecular Mimics to Probe Intermolecular Interaction Landscapes William V. Williams, Thomas Kieber-Wmmons, David B. Weiner, and Mark I. Greene   * Affinity Maturation and Leaning in Immune Networks Grard Weisbuch and Alan S. Perelson   * Auto-Anti-Idiotype and Antigen as Selective Factors Driving B-Cell Affinity Maturation in the Immune System Gregory W. Siskind   * Somatic Mutation and the Antibody Repertoire: A Computational Model of Shape Space Richard G. Weinand    Applied Molecular Evolution * Evolution of Proteins from Random Sequences: A Model for the Protein Sequence Space and an Experimental Wlodek Mandecki   * Studies in the Evolution of Biological Activity from Random Sequences Marshall S. Z. Horwitz, Dipak K. Dube, and Lawrence A. Loeb   * The Catalytic Potential of RNA Debra L. Robertson and Gerald F. Joyce    Origin of Life Models * Dynamics of Autocatalytic Reaction Networks P. Schuster