Molecular Basis of Lymphokine Action

Front Matter....Pages i-xxviii
Front Matter....Pages 1-1
Tumor Growth Factors....Pages 3-12
Front Matter....Pages N1-N1
Suppressor T Cell Receptor and Functional Molecule....Pages 13-20
Role of Glycosylation Inhibiting Factor (GIF), a Phospholipase Inhibitory Protein, in the Generation of Antigen-Specific Suppressor T Cells....Pages 21-31
Characterization of GAT-Specific Suppressor Factors and Comparison to Other Antigen-Specific Factors....Pages 33-46
Soluble Immune Response Suppressor (SIRS) Mediated Inhibition of Cell Division....Pages 47-58
Differentiation and Proliferation of CD8 + Suppressor T Lymphocytes....Pages 59-71
Front Matter....Pages 72-72
Molecular Studies on Murine Interleukin 1....Pages 73-81
Multiple Biological Activities of Human Interleukin-1....Pages 83-95
A Membrane form of IL-1 — Identification and Control of Expression....Pages 97-104
Characterization of Interleukin-1 Receptors....Pages 105-116
T Cell Interleukin 1....Pages 117-122
Front Matter....Pages N2-N2
Molecular structure and immunological function of human B cell differentiation factor (BSF2)....Pages 123-136
Current Studies Examining Regulation of the Human B Cell Cycle....Pages 137-148
Two Types of Mouse Helper T Cell Clone: Differences in B Cell Help and Lymphokine Synthesis....Pages 149-159
Front Matter....Pages 160-160
Two Step Activation of the Interleukin-2 Autocrine Loop May be Involved in ATL Development....Pages 161-169
The Human High Affinity Interleukin-2 Receptor....Pages 171-179
Regulation of IL2 and Related Genes at the mRNA Level....Pages 181-191
Effects of Interleukin 2 to Promote Prothymocyte and Early Thymocyte Proliferation and Differentiation and to Increase Cyclic GMP Levels....Pages 193-206
Biological Significance of Interleukin 2 Receptor Associated Molecules....Pages 207-216
Identification of a Novel Interleukin-2 Receptor Subunit....Pages 217-221
Front Matter....Pages 222-222
 In vivo Antitumor Activities of Tumor Necrosis Factor-Alpha....Pages 223-232
Life after IL2....Pages 233-244
Regulatory Polypeptides in the Lympho-Hemopoietic System....Pages 245-260
Cachectin/TNF: A Mediator of Lethal Endotoxemia....Pages 261-269
The Molecular Complex of Macrophage Migration Inhibitory Activity (MIF) and its Role in Inflammatory Reactions....Pages 271-281
Front Matter....Pages 282-282
Molecular Biology of Interleukin-3....Pages 283-294
The Molecular and Biological Properties of the Human and Murine Members of the CSF-1 Family....Pages 295-311
Isolation and Characterization of Mouse and Human cDNA Clones Encoding IL-4 and IgA-Enhancing Factor/Eosinophil CSF (IL-5)....Pages 313-324
Molecular Cloning and Characterization of the Human Gene for Interleukin-3 (IL-3)....Pages 325-337
Structure-Function Studies of Lymphokines by Total Chemical Synthesis....Pages 339-351
Front Matter....Pages 352-352
Cytokines in Metabolic Bone Disease....Pages 353-358
Lymphokine Production in Autoimmunity: Usefulness of mRNA Assays....Pages 359-369
Interleukin-2 Receptor Directed Immunosuppressive Therapy....Pages 371-392
An Improved Method for the Generation of Human Activated Killer Cells....Pages 393-407
Growth and Differentiation Factors for Human Metachromatically Staining Cells....Pages 409-418
Front Matter....Pages N3-N3
Lymphokine Research and the Biology of Immunologic Diseases....Pages 419-428
Front Matter....Pages N4-N4
Summary of the Interleukin 1 Workshop Discussions....Pages 429-441
Hematopoietic Growth Factors....Pages 443-447
Fifth International Lymphokine Workshop: Summary of Suppressor/Effector Factors Session....Pages 449-453
Clinical Uses of Lymphokines Workshop Summary....Pages 455-461
Front Matter....Pages N4-N4
Workshop Summary: Interleukin 2....Pages 463-469
Summary of Workshop on “Lymphokines Activating Cells for Killer Functions”....Pages 471-474
B Cell Stimulatory Factors....Pages 475-478
Back Matter....Pages 479-481