Microsomes, Drug Oxidations and Chemical Carcinogenesis

Content: 
Front Matter, Page iii
Copyright, Page iv
RATE-LIMITING FACTORS IN XENOBIOTIC METABOLISM BY CYTOCHROME P-450, SULPHOTRANSFERASE, AND GLUCURONYL TRANSFERASE, Pages 619-626, J.W. Bridges, P. Wiebkin, J.R. Fry
EPOXIDE HYDRATASE, Pages 627-635, F. Oesch
KINETIC STUDIES ON MECHANISM AND SUBSTRATE SPECIFICITY OF THE MICROSOMAL FLAVIN–CONTAINING MONOOXYGENASE, Pages 637-645, Daniel M. Ziegler, Lawrence L. Poulsen, Michael W. Duffel
EPOXIDE HYDRATASE AND ITS MEMBRANE ENVIRONMENT, Pages 647-650, P. Bentley, P. Stasiecki, F. Waechter, W. Stäubli, F. Oesch
INTERINDIVIDUAL VARIATIONS OF EPOXIDE HYDRATASE ACTIVITY IN HUMAN LIVER AND LUNG BIOPSIES, LYMPHOCYTES AND FIBROBLAST CULTURES, Pages 651-654, H.R. Glatt, J. Lorenz, R. Fleischmann, H. Remmer, E.E. Ohnhaus, E. Kaltenbach, F. Tegtmeyer, H. Rüdiger, F. Oesch
EXTRAMICROSOMAL EPOXIDE HYDRATION, Pages 655-658, B.D. Hammock, M. El Tantawy, S.S. Gill, L. Hasagawa, C.A. Mullin, K. Ota
METABOLISM OF BENZO(A)PYRENE BY LIPOSOMES CONTAINING PURIFIED MICROSOMAL DRUG-METABOLIZING ENZYMES, Pages 659-662, Peter Mackenzie, Matti Lang, Osmo Hänninen
COMPARISON OF GLUTATHIONE S-TRANSFERASES FROM RAT TISSUES WITH THE ACTIVITY IN HUMAN PLACENTA, Pages 663-666, B. Mannervik, C. Guthenberg, K. Åkerfeldt
FORMATION, METABOLISM, AND EXCRETION OF CONJUGATES OF PARACETAMOL, Pages 667-670, Peter Moldèus, Roland Grafström, Kari Ormstad, Sten Orrenius
SUBCELLULAR LOCALIZATION OF GLUTATHIONE S-TRANSFERASE ACTIVITY IN RAT LIVER, Pages 671-674, R. Morgenstern, J. Meijer, J.W. DePierre, L. Ernster
BILIARY METABOLITES OF BENZO(a)PYRENE 4,5-OXIDE IN THE RAT, Pages 675-678, John L. Plummer, Brian R. Smith, John R. Bend
HEPATIC AND EXTRAHEPATIC GLUTATHIONE S–TRANSFERASE ACTIVITIES IN VITAMIN A DEFICIENCY, Pages 679-682, Z.H. Siddik, E.G. Mimnaugh, M.A. Trush, T.E. Gram
PULMONARY METABOLISM AND EXCRETION OF ARENE OXIDES, Pages 683-686, Brian R. Smith, John L. Plummer, John R. Bend
METABOLISM OF ARYLAMINES: EVIDENCE FOR COMMON GENETIC CONTROL OF ARYLHYDROXAMIC ACID ACYLTRANSFERASE (AHAT) AND GENETICALLY POLYMORPHIC N-ACETYLTRANSFERASE (NAT) OF RABBIT LIVER, Pages 687-690, Irene B. Glowinski, Wendell W. Weber, Jacquelene M. Fysh, Jimmie B. Vaught, Charles M. King
PARTIAL PURIFICATION OF GLUTATHIONE (GSH)-S-ARYL- AND EPOXIDE-TRANSFERASE(S) OF TRYPANOSOMA CRUZI, Pages 691-694, Aminadav Yawetz, Moises Agosin
PURIFICATION AND PROPERTIES OF UDP-GLUCURONYLTRANSFERASE FROM RABBIT LIVER MICROSOMES, Pages 695-698, A. Yuasa, R. Sato
CHOLESTEROL 7α -HYDROXYLASE IN RAT LIVER MICROSOMES - CHARACTERISTICS, SOLUBILISATION, RESOLUTION, AND SUBSTRATE SPECIFICITY, Pages 699-708, G.S. BOYD, N.G. HATTERSLEY, S. OZASA, K.E. SUCKLING
LAURATE HYDROXYLATION AND DRUG METABOLISM IN PIG LIVER AND KIDNEY MICROSOMES AND IN RECONSTITUTED SYSTEMS FROM PIG LIVER AND KIDNEY, Pages 709-720, B.S.S. Masters, Y. Yasukochi, R.T. Okita, L.K. Parkhill, H. Taniguchi, J.H. Dees
PRODUCT SPECIFICITY AND REGULATION OF TWO LAURATE HYDROXYLASES IN HIGHER PLANTS, Pages 721-724, J-P. Salaün, I. Benveniste, D. Reichhart, R. Feyereisen, F. Durst
EFFECT OF PHENOBARBITAL ON TRIGLYCERIDE METABOLISM IN THE RAT, Pages 725-728, D.M. Goldberg, M.W. Roomi, A. Yu, D.A.K. Roncari
ω-AND (ω-1)-HYDROXYLATION OF FATTY ACIDS IN RABBIT INTESTINAL MUCOSA MICROSOMES, Pages 729-732, Kosuke Ichihara, Ikuko Kasaoka, Emi Kusunose, Masamichi Kusunose
THE ROLE OF CYTOCHROME b5 IN THE LIVER MICROSOMAL ELONGATION OF FATTY ACIDS, Pages 733-736, S.R. Keyes, I. Jansson, D.L. Cinti
EVIDENCE FOR DIFFERENT HEPATIC MONOOXYGENASES IN (ω-1)- AND ω-HYDROXYLATION OF PROSTAGLANDINS, Pages 737-740, D. Kupfer, G.K. Miranda, A. Theoharides, D.E. Piccolo
EFFECT OF INDUCING AGENTS AND CYTOCHROME P–450 INHIBITORS ON LAURATE HYDROXYLASE ACTIVITIES IN RAT LIVER MICROSOMES, Pages 741-744, R.T. Okita, R.A. Prough, B.S.S. Masters
STEROID HYDROXYLASES IN LIVER MICROSOMES AND MITOCHONDRIA, Pages 745-748, Kyuichiro Okuda, Yohko Atsuta, Kuniko Murakami, Chieko Wakeshima
C-21 AND 6α-HYDROXYLATION OF PROGESTERONE BY SOLUBILIZED RABBIT HEPATIC MICROSOMAL FRACTIONS: NONOBLIGATORY REQUIREMENT FOR CYTOCHROME P450, Pages 749-752, I.R. Senciall, S. Rahal, A.C. Dey
MICROSOMAL LIPID PEROXIDATION: CATALYSIS, EFFECTS, AND INHIBITION BY CYTOSOLIC PROTEIN, Pages 753-759, R. Talcott, A. Ketterman, W. Harger, H. Denk, D. Kerjaschki, I. Zeiler, R. Eckerstorfer
CYTOCHROME P-450-CONTAINING MONOOXYGENASE SYSTEM OF YEAST MICROSOMES. PROPERTIES AND ROLE IN STEROL BIOSYNTHESIS, Pages 761-764, Yuzo Yoshida, Yuri Aoyama
STUDIES ON LIVER AND KIDNEY DRUG AND LAURIC ACID MONOOXYGENASES IN BOTH MICROSOMAL AND RECONSTITUTED SYSTEMS, Pages 765-768, Y. Yasukochi, R.T. Okita, B.S.S. Masters
LIPID PEROXIDATION INDUCED BY GLUTATHIONE DEPLETION, Pages 769-772, J. Högberg, I. Anundi, A. Kristoferson, J. Rajs
METABOLISM OF JUVENILE HORMONE (JH) MIMICS BY A RECONSTITUTED RAT LIVER CYTOCHROME P-450 PREPARATION, Pages 773-776, A. Morello, Y. Repetto, R.A. White, R.K. Hill, M. Agosin
AN OVERVIEW OF THE ROLE OF MICROSOMAL ENZYMES IN THE FORMATION OF TOXIC METABOLITES, Pages 777-789, James R. Gillette
MICROSOMAL ENZYMES AND THE TOXICITY OF THIONO-SULFUR COMPOUNDS, Pages 791-799, R.A. Neal
THE Ah LOCUS. GENETIC DIFFERENCES IN TOXIC AND TUMORIGENIC RESPONSE TO FOREIGN COMPOUNDS, Pages 801-812, Daniel W. Nebert
COMPARISON OF CAFFEINE METABOLISM BY PERFUSED RAT LIVER AND ISOLATED MICROSOMES, Pages 813-816, Maurice J. Arnaud, Christelle Welsch
RHYTHMIC RESPONSE OF THE HEPATIC 2- AND 4-BIPHENYL HYDROXY-LASE IN RATS TO DRUGS UPON INTERMITTENT TREATMENT, Pages 817-820, E. Bachmann, G. Zbinden
FUNCTIONAL CHANGES OF HEPATIC ENDOPLASMIC RETICULUM BY ADVERSE DRUG TREATMENT, Pages 821-824, F.A. de la Iglesia, C.J. DiFonzo, S. Pinn, R.A. Martin, R. Farkas, G. Feuer
A PROCEDURE FOR ISOLATION OF RABBIT PULMONARY EPITHELIAL CELLS FOR STUDY OF FOREIGN COMPOUND METABOLISM, Pages 825-828, Theodora R. Devereux, James R. Fouts
THE FORMATION OF AMPHETAMINE METABOLIC INTERMEDIATE COMPLEXES WITH CYTOCHROME P-450 IN MICROSOMES AND INTACT TISSUES, Pages 829-832, Michael R. Franklin, Judy L. Gumbrecht
COMPARATIVE ASPECTS OF HEPATIC MONOOXYGENASE INDUCTION IN RAT AND RAINBOW TROUT BY SEVERAL PCB ISOMERS, Pages 833-836, Ronald B. Franklin, Clifford R. Elcombe, Mary Jo Vodicnik, John J. Lech
GENETIC AND ENVIRONMENTAL INFLUENCES ON TOLBUTAMIDE METABOLISM, Pages 837-840, T.G. Geary, B.N. La Du Jr.
ETHCHLORVYNOL: POTENTIAL OF METABOLITES FOR ADVERSE EFFECTS IN MAN, Pages 841-844, J.P. Horwitz, W. Brukwinski, J. Treisman, D. Andrzejewski, E.B. Hills, H.L. Chung, C.Y. Wang
IRREVERSIBLE BINDING OF 6-THIOPURINE TO RAT HEPATIC MICROSOMAL PROTEINS IN VITRO AND IN VIVO, Pages 845-848, Richard M. Hyslop, Ian Jardine
ACTIVATION OF A PROESTROGEN — METHOXYCHLOR (DDT ANALOG) — BY HEPATIC MONOOXYGENASE, Pages 849-852, W.H. Bulger, R.M. Muccitelli, D. Kupfer
EFFECTS OF SOME FLAME RETARDANTS ON THE LIVER MICROSOMAL ENZYME SYSTEMS), Pages 853-856, Per Lundberg
THE DEVELOPMENT OF HEPATIC MIXED-FUNCTION OXIDASES - WARFARIN METABOLISM AS A PROBE, Pages 857-860, M.G. MacDonald, L.S. Kaminsky
LOSS AND RECOVERY OF HEPATIC MONOOXYGENASE ACTIVITIES AFTER THE ADMINISTRATION OF ALLYLISOPROPYLACETAMIDE (AIA) TO MICE, Pages 861-864, Laurel Deloria, Joseph Low, Gilbert J. Mannering
METABOLISM OF FLUROXENE AND ANALOGOUS FLUORINATED ETHER ANESTHETICS BY HIGHLY PURIFIED CYTOCHROMES P-450 AND THE ASSOCIATED ENZYME DESTRUCTION, Pages 865-868, M.J. Murphy, F.P. Guengerich, L.S. Kaminsky
EVALUATION OF 4-FORMYLAMINOANTIPYRINE AND OTHER N-DEMETHYLATED PRODUCTS OF AMINOPYRINE IN HEPATIC MICROSOMES BY HPLC, Pages 869-872, S. Nigam, B. Raack, I. Roots, G. Heinemeyer, A.G. Hildebrandt
THE EFFECT OF SELENIUM AND VITAMIN E DEFICIENCY ON THE TOXICITY OF NITROFURANTOIN IN THE CHICK, Pages 873-876, Francis J. Peterson, Ronald P. Mason, Jordan L. Holtzman, Gerald F. Combs Jr.
THE REDUCTIVE METABOLISM OF CARBON TETRACHLORIDE IN RECONSTITUTED MONOOXYGENASE SYSTEMS, Pages 877-880, Richard M. Philpot, Wolfgang M. Nastainczyk, Ronald P. Mason, C. Roland Wolf
OXIDATIVE BIOACTIVATION OF HALOFORMS INTO HEPATOTOXINS, Pages 881-884, L.R. Pohl, J.L. Martin, A.M. Taburet, J.W. George
EFFECTS OF ISONIAZID METABOLITES ON THE RATE OF HEPATIC MICROSOMAL DEFLUORINATION OF VOLATILE FLUORINATED ETHER ANESTHETICS, Pages 885-888, Susan A. Rice, M. Pamela Fish
EFFECTS OF INDOLE DERIVATIVES ON MONOOXYGENASE ACTIVITY IN RABBIT LIVER MICROSOMES, Pages 889-892, Howard G. Shertzer
COINCIDENT INDUCTION OF CYTOCHROME P450 AND PHENOL RED CONJUGATION IN CULTURED CHICK EMBRYO HEPATOCYTES: EFFECTS OF COBALTOUS AND MANGANOUS IONS, Pages 893-896, Peter Sinclair, Jacqueline Sinclair, William Bement, Andrea Farnham, Joanne Pomeroy, Herbert Bonkowsky
BENZENE METABOLISM AND TOXICITY IN CD-1, C57/B6, AND DBA/2N MICE, Pages 897-902, S.L. Longacre, J.J. Kocsis, R. Snyder
HEPATOTOXICITY DUE TO TETRACHLORODIBENZO(p) DIOXIN DEPENDS UPON AHH RESPONSIVENESS AND NONHEMOPROTEIN IRON, Pages 903-906, G.D. Sweeney, K.G. Jones, F.M. Cole
THE MECHANISM OF CYTOCHROME P-450-MEDIATED CYTOTOXICITY STUDIED WITH ISOLATED HEPATOCYTES EXPOSED TO BROMOBENZENE, Pages 907-911, H. Thor, S. Thorold, S. Orrenius
THE INFLUENCE OF THE NUTRITIONAL STATE ON RATES OF p-NITROANISOLE 0-DEMETHYLATION AND p-NITROPHENOL CONJUGATION IN PERFUSED RAT LIVERS, Pages 913-916, Ronald G. Thurman, Lester A. Reinke, Steven A. Belinksy, Frederick C. Kauffman
ACUTE DECLINE OF HEPATIC MICROSOMAL MONOOXYGENASE ACTIVITY AND OTHER PROPERTIES BY MORPHINE SULFATE, Pages 917-920, Th.A. van der Hoeven, R.P. Linnet
SUBSTITUENT EFFECTS ON TOXICITY AND COVALENT BINDING OF BROMOBENZENE DERIVATIVES, Pages 921-924, R.A. Wiley, R.P. Hanzlik, T. Gillesse
HEPATIC MICROSOMAL EPOXIDATION OF BROMOBENZENE TO PHENOLS AND ITS TOXICOLOGICAL IMPLICATION, Pages 925-928, S.S. Lau, G.D. Abrams, V.G. Zannoni
TOXICITY OF 2-CHLOROBENZYLIDENE MALONONITRILE AND HEPATIC MICROSOMAL MIXED FUNCTION OXIDASE SYSTEM, Pages 929-932, Sitaram S. Pawar, Manvendra S. Kachole, Umakant K. Halde
ALTERATION OF MICROSOMAL MONOOXYGENASE ACTIVITIES BY COBALT PRETREATMENT OF MICE, Pages 933-936, W. Legrum, G. Stuehmeier, K.J. Netter
CHARACTERISTICS OF THE MICROSOMAL AND MITOCHONDRIAL DEAMINATION OF BENZYLAMINE, Pages 937-940, P.M. Bélanger, M. Lalande
OXIDATION OF N-HYDROXY-AMPHETAMINE AND -PHENTERMINE BY ACTIVE OXYGEN, Pages 941-944, A.K. Cho, M.S. Maynard, R.M. Matsumoto
N-METHYLCARBAZOLE METABOLISM: A PROBE FOR CHARACTERIZING THE MULTIPLE FORMS OF CYTOCHROME P-450, Pages 945-948, D.R. Koop, D.P. Gurka, P.F. Hollenberg
INCREASED ACTIVITY OF THE PENTOSE PATHWAY AFTER ADMINISTRATION OF trans-STILBENE OXIDE, Pages 949-952, J. Seidegård, J.W. DePierre, L. Ernster
INTERACTIONS BETWEEN ENERGY METABOLISM AND MIXED-FUNCTION OXIDATION IN PERFUSED RAT LIVER, Pages 953-956, Lester A. Reinke, Marion Danis, Steven A. Belinksy, Ronald G. Thurman, Frederick C. Kauffman
EVIDENCE FOR MORE THAN ONE FORM OF CYTOCHROME P-450 IN HEPATIC MICROSOMAL FRACTIONS OF HUMAN LIVER SAMPLES, Pages 957-960, A.R. Boobis, M.J. Brodie, G.C. Kahn, D.S. Davies
THE IN VITRO METABOLISM OF 3-ACETYLPYRIDINE, 3-ACETYLPYRIDINE-N-OXIDE, AND 1-(-3-PYRIDYL)-ETHANOL, Pages 961-964, J.W. Gorrod, J. Bryan, D.A. Cowan, L.A. Damani
STUDIES ON SEX DIFFERENCES IN THE O-DEALKYLATION ACTIVITIES OF 7-HYDROXYCOUMARIN O-ALKYL DERIVATIVES IN LIVER MICROSOMES OF RATS, Pages 965-968, T. Kamataki, M. Ando, Y. Yamazoe, K. Ishii, R. Kato
AUGMENTATION BY HEMATIN OF RATES OF BENZO[a]PYRENE HYDROXYLATION: THE POSSIBLE INVOLVEMENT OF CYTOCHROME P-450, Pages 969-972, Curtis J. Omiecinski, Mont R. Juchau
MULTIPLICITY OF NADPH- AND NADH-SUPPORTED N- AND O-DEALKYLATING SYSTEMS OF HEPATIC MICROSOMES, Pages 973-976, Shin-ichi Kuwahara, Gilbert J. Mannering
4-CHLOROBIPHENYL HYDROXYLASE: A MONOOXYGENASE PREFERENTIALLY INDUCED BY 3-METHYLCHOLANTHRENE, Pages 977-980, A. Parkinson, L. Copp, S. Safe
NADH-AND NADPH-DEPENDENT REDUCTION OF INDICINE N-OXIDE BY MICROSOMAL CYTOCHROME P-450, Pages 981-984, G. Powis, L. Wincentsen
METABOLISM AND IRREVERSIBLE BINDING OF PHENCYCLIDINE BY RABBIT LUNG AND LIVER MICROSOMES, Pages 985-988, F.C.P. Law, T.E. Farquharson
CLEAVAGE OF VICINAL DIOLS BY LIVER MICROSOMES, Pages 989-992, P. Laskowski, C. Chen
CHARACTERISATION OF THE FORM OF P-450 INDUCED BY METHYLENE-DIOXY COMPOUNDS IN RATS AND MICE, Pages 993-996, J.W. Bridges, T.R. Fennell
INTERACTION OF THE ENZYME INDUCER, HOE 17,879, WITH MICROSOMAL ENZYME SYSTEMS, Pages 997-1000, Friedrich E. Beyhl
RELATION BETWEEN IN VITRO ALTERATION BY ALLYL COMPOUNDS AND FORMS OF CYTOCHROME P-450, Pages 1001-1004, V. Luu-The, J. Cumps, P. Dumont
THE RAPID ACTIVATION OF P-450-MEDIATED METABOLISM BY CORTICOSTEROIDS, Pages 1005-1008, J.W. Bridges, D. Benford, D.V. Parke
METABOLISM IN VITRO OF CAPSAICIN, A PUNGENT PRINCIPLE OF RED PEPPER, WITH RAT LIVER HOMOGENATES, Pages 1009-1012, Sang Sup Lee, Satyendra Kumar
METABOLISM OF BENZO(A)PYRENE AND ONCOGENIC TRANSFORMATION OF C3H/10T1/2 MOUSE EMBRYO FIBROBLASTS, Pages 1013-1024, Charles Heidelberger, E.B. Gehly, W.E. Fahl, Colin R. Jefcoate
AN OVERVIEW OF THE SALMONELLA MUTAGENICITY TEST, Pages 1025-1040, Bruce N. Ames, Lynne Haroun
BAY-REGION ACTIVATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO ULTIMATE MUTAGENS AND CARCINOGENS, Pages 1041-1051, D.M. Jerina, H. Yagi, D.R. Thakker, R.E. Lehr, A.W. Wood, W. Levin, A.H. Conney
BIOTRANSFORMATION OF BENZO(a)PYRENE TO DNA-BINDING PRODUCTS BY ISOLATED HEPATOCYTES, Pages 1053-1064, Bengt Jernström, Thomas Guenthner, Lennart Dock, Sten-Åke Svensson, Sten Orrenius
CATALYTIC ACTIVITY AND STEREOSPECIFICITY OF PHENOBARBITAL-INDUCIBLE AND 5,6-BENZOFLAVONE-INDUCIBLE ISOZYMES OF LIVER MICROSOMAL CYTOCHROME P-450 IN THE OXYGENATION OF BENZO[a]-PYRENE AND trans-7,8-DIHYDROXY-7,8-DIHYDROBENZO[a]PYRENE, Pages 1065-1080, K.P. Vatsis, J. Deutsch, H.V. Gelboin, M.J. Coon
METABOLISM OF NITROSAMINES: AN OVERVIEW, Pages 1081-1092, Peter N. Magee
SPECIES DIFFERENCES IN MICROSOMAL ACTIVATION OF MUTAGENS AND CARCINOGENS, WITH SPECIAL REFERENCE TO NEW POTENT MUTAGENS FROM PYROLYSATES OF AMINO ACIDS AND PROTEINS, Pages 1093-1102, Taijiro Matsushima, Takie Yahagi, Yuji Takamoto, Minako Nagao, Takashi Sugimura
MICROSOMES AND DRUG OXIDATIONS: PERSPECTIVES AND CHALLENGES, Pages 1103-1118, A.H. Conney
CATALYTIC PROPERTIES OF MICROSOMAL AND PURIFIED EPOXIDE HYDROLASE TOWARD K-REGION ARENE OXIDES, Pages 1119-1123, R.N. Armstrong, W. Levin, D.M. Jerina
DRUG-METABOLIZING SYSTEMS IN THE LIVER OF THE NORTHERN PIKE, ESOX LUCIUS, Pages 1125-1128, L. Balk, J. Meijer, J. Seidegård, R. Morgenstern, J.W. DePierre
DIETARY PROTEIN AND MIXED FUNCTION OXIDASE ACTIVITY, Pages 1129-1132, Steven K. Clinton, C. Richard Truex, Peter B. Imrey, Willard J. Visek
THE METABOLISM OF 1,2-DISUBSTITUTED HYDRAZINES IN ISOLATED HEPATOCYTES, Pages 1133-1136, M.W. Coomes, P. Wiebkin, R.A. Prough
MUTAGENICITY AND METABOLISM OF CYCLOPENTA(cd)PYRENE, Pages 1137-1140, Eric Eisenstadt, Avram Gold
SOME CHARACTERISTICS OF THE DRUG-METABOLIZING ENZYMES IN ISOLATED HEPATIC NUCLEI, Pages 1141-1144, L.S. Gontovnick, G.D. Bellward
MICROSOMAL METABOLISM OF DIALLYLNITROSAMINE, Pages 1145-1148, C.J. Grandjean, S. Knepper, N. Morris
MUTANTS OF CULTURED HEPATOMA CELLS DEFICIENT IN ARYL HYDROCARBON HYDROXYLASE, Pages 1149-1152, Oliver Hankinson
QUALITATIVE AND QUANTITATIVE STUDIES OF DNA-BINDING METABOLITES OF BENZO(a)PYRENE BY FLUORESCENCE SPECTROSCOPY, Pages 1153-1156, Bengt Jernström, Lennart Dock, Ola Undeman, Astrid Gräslund
USE OF THE AMES ASSAY FOR STUDYING FACTORS AFFECTING THE ACTIVATION OF 2-AMINOANTHRACENE TO MUTAGENIC METABOLITES, Pages 1157-1160, J.C. Kawalek, A.W. Andrews
CYTOCHROME P-450 FORM 4, A MAJOR DETERMINANT OF 2-AMINOANTHRACENE MUTAGENESIS, Pages 1161-1164, R.L. Norman, E.F. Johnson, U. Müller-Eberhard
RAT HEPATOCYTES IN PRIMARY MONOLAYER CULTURE: A TOOL FOR INVESTIGATING THE REGULATION OF CARCINOGEN METABOLISM, Pages 1165-1168, Debra P. Gayda, Michael W. Pariza
THE METABOLISM OF 3- AND 9-HYDROXYBENZO(a)PYRENE BY RAT LIVER MICROSOMAL FRACTIONS, Pages 1169-1172, J. Capdevila, R.A. Lubet, R.A. Prough
EFFECT OF CHRONIC ETHANOL CONSUMPTION ON MICROSOMAL ENZYMES: POTENTIAL RELATIONSHIP TO CHEMICAL MUTAGENESIS AND CARCINOGENESIS, Pages 1173-1176, Helmut K. Seitz, Anthony J. Garro, Charles S. Lieber
CHARACTERIZATION OF THE CYTOCHROME P-450-CONTAINING MIXED FUNCTION OXIDASE SYSTEM OF RAT COLON, Pages 1177-1180, H.W. Strobel, W.F. Fang, R.J. Oshinsky
INDUCTION OF N- AND C-HYDROXYLATIONS OF 2-ACETYLAMINOFLUORENE IN RAT HYPERPLASTIC LIVER NODULES AND HEPATOMAS, Pages 1181-1184, S.S. Thorgeirsson, D.S. Levitt, C.L. Smith
MULTIPLE ACTIVATION PATHWAYS OF 7,12-DIMETHYLBENZ[a]ANTHRACENE, Pages 1185-1188, Shen K. Yang, George D. Easton, Ming W. Chou
INFLUENCE OF MODIFIERS OF MFO ACTIVITY ON THE IN VITRO METABOLISM OF CYCLIC NITROSAMINES, Pages 1189-1192, G. David McCoy, Chi-hong B. Chen, Stephen S. Hecht
AUTOCATALYZED COVALENT BINDING OF 3H(−)t-7,8-DIOL BENZO(a)PYRENE TO MIXED-FUNCTION OXIDASE ENZYMES AND DNA: THE ROLE OF EPOXIDE HYDRATASE, Pages 1193-1197, E.M. Gozukara, G. Belvedere, J. Deutsch, M.J. Coon, F.P. Guengerich, H.V. Gelboin
REGULATION OF DNA MODIFICATION BY SELECTIVE CONJUGATION OF BENZO(a)PYRENE METABOLITES, Pages 1199-1202, W.E. Fahl, A.L. Shen, G. Keller, S.A. Wrighton, C.R. Jefcoate
METABOLISM OF BENZO(a)PYRENE IN LITTLE SKATE MIXED-FUNCTION OXIDASE SYSTEMS, Pages 1203-1206, Louise M. Ball, Tahani H. Elmamlouk, John R. Bend
INDUCIBILITY OF THE METABOLISM OF BENZO[a]PYRENE BY POLYCHLORINATED BIPHENYLS (PCBs) IN LIVER AND LUNG MICROSOMAL PREPARATIONS FROM RATS AND RABBITS, Pages 1207-1210, Alvito P. Alvares, Julie L. Eiseman, Shen K. Yang
COVALENT BINDING OF VINYL CHLORIDE METABOLITES IN VITRO: ROLES OF CYTOCHROME P-450, NADPH-CYTOCHROME P-450 REDUCTASE, EPOXIDE HYDRATASE, AND ALCOHOL DEHYDROGENASE, Pages 1211-1214, F.P. Guengerich, W.M. Crawford Jr., P.S. Mason, M.B. Mitchell, P.G. Watanabe
EVIDENCE FOR INHIBITORY COMPLEXES FORMED WITH CYTOCHROME P-450 AND A METABOLITE OF 1,1-DISUBSTITUTED HYDRAZINES, Pages 1215-1218, R.N. Hines, R.A. Prough
OVARIAN ARYL HYDROCARBON HYDROXYLASE ACTIVITY AND OOCYTE DESTRUCTION, Pages 1219-1222, Donald R. Mattison, Raymond H. Menard, Snorri S. Thorgeirsson
BINDING OF REACTIVE METABOLITES OF AROMATIC HYDROCARBONS TO SPECIFIC MICROSOMAL PROTEINS, Pages 1223-1226, Anders Tunek, Cecilia Schelin, Bengt Jergil
SECONDARY OXYGENATION OF THE CARCINOGEN 2-ACETYLAMINOFLUORENE (= 2-AAF) IN VITRO AND IN VIVO, Pages 1227-1230, W. Lenk, R. Rosenbauer-Thilmann
METABOLISM OF 7,12-DIMETHYLBENZ(a)ANTHRACENE IN RAT ADRENALS, Pages 1231-1234, Johan Montelius, Jan Rydstrüm
THE INFLUENCE OF ORGANIC SOLVENTS ON CYTOCHROME P-450-MEDIATED METABOLISM OF BIPHENYL AND BENZO(A)PYRENE, Pages 1235-1238, O.G. Nilsen, R. Toftgård
EFFECTS OF ESTRONE, ESTRADIOL AND ESTRIOL PRETREATMENT ON HEPATIC, LUNG, AND INTESTINAL ARYL HYDROCARBON HYDROXYLASE ACTIVITIES IN FEMALE RATS, Pages 1239-1242, S.J. Stohs, W.A. Al-Turk, E.B. Roche
FORMATION OF BENZO(A)PYRENE METABOLITES IN ISOLATED INTESTINAL SACS, Pages 1243-1246, Eino Hietanen, Osmo Hänninen, Matti Lang
INDEX, Pages 1247-1258