Microbial Toxins in Foods and Feeds: Cellular and Molecular Modes of Action

Front Matter....Pages i-xvii
UJNR Panel on Toxic Microorganisms....Pages 1-15
Front Matter....Pages 17-17
Overview Of Bacterial Toxins with a Nonreductionist Approach to the Mode of Action of Botulinal Neurotoxin....Pages 19-36
ADP-Ribosylation of Actin by Clostridial Toxins....Pages 37-44
Mechanisms of Action, Diagnostic and Rapid Methods of Analysis of Staphylococcus Aureus Enterotoxins ....Pages 45-56
Genetic Analysis of Regulation and Structure of Shiga-Like Toxin I in Escherichia Coli ....Pages 57-64
Characterization of 50-Kilobase Plasmid of Salmonella Choleraesuis Strain AH1-S44....Pages 65-73
Primary Structure and Conformation of Clostridium Botulinum Neurotoxin....Pages 75-89
The Escherichia Coli/Vibrio Cholerae Family Of Enterotoxins....Pages 91-102
Structure and Function of Clostridium Botulinum Derivative Toxin Analyzed with Monoclonal Antibodies....Pages 103-110
Rapid Method for Detection of Pathogenic Yersinia Enterocolitica and Yersinia Pseudotuberculosis Using Enzyme Immunoassay....Pages 111-118
Oligodeoxyribonucleotide Probe Specific For The 230 Kilobase Pair Virulence Plasmid in Enteroinvasive Escherichia Coli and Shigella ....Pages 119-126
Usefulness in the Epidemiology of Food Poisoning Cases of Detection of Specific Restriction Endonucleases in Some Serotypes of Salmonella and Yersinia ....Pages 127-129
Genetics of Thermostable Direct Hemolysin of Vibrio Parahaemolyticus ....Pages 131-135
Genetic Aspects of Clostridium Botulinum ....Pages 137-143
Molecular Structure and Biological Activities of Clostridium Botulinum C 2 Toxin....Pages 145-157
Genetic Studies on Vibrio Fluvialis and its Enterotoxins....Pages 159-171
Molecular Structure of Clostridium Botulinum Progenitor Toxins....Pages 173-180
Purification and Characterization of Bacillus Cereus Enterotoxin and its Application to Diagnosis....Pages 181-193
Mode of Action of Shiga and Shiga-Like Toxins....Pages 195-201
Structure and Function of Clostridium Perfringens Enterotoxin....Pages 203-212
Front Matter....Pages 17-17
Biochemical Characteristics and Actions of Toxins from Clostridium Difficile Isolated From Antibiotic Associated Diarrhea in Japan....Pages 213-223
Restriction Enzyme Analysis in the Epidemiology of Listeria Monocytogenes ....Pages 225-238
Molecular Genetic Analysis of Virulence Factors of Shigella Flexneri ....Pages 239-245
Front Matter....Pages 247-247
Mycotoxins and Mycotoxicoses: Overview....Pages 249-259
Interaction of T-2 Toxin with Cell Membranes....Pages 261-274
Biotransformation as a Determinant of Species Susceptibility to Aflatoxin B 1 : In Vitro Studies in Rats, Mouse, Monkey, and Human Liver....Pages 275-290
The GABA Receptor and the Action of Tremorgenic Mycotoxins....Pages 291-295
Application of Macromolecular Synthesis Measurements in Mycotoxin Toxicity Studies....Pages 297-324
Use of Aflatoxin-DNA and Protein Adducts for Human Dosimetry....Pages 325-334
Analysis of Aflatoxin B 1 - DNA Adducts....Pages 335-341
Production and Characterization of a Monoclonal Antibody to Tetraacetylnivalenol....Pages 343-347
Interaction of Aflatoxin B 1 within Specific Gene Sequences....Pages 349-362
Immunologic in Vivo Detection of Aflatoxin B 1 - DNA Adducts in Rats and Rainbow Trout....Pages 363-367
The Mode of Action of Anthraquinone Mycotoxins on ATP Synthesis in Mitochondria....Pages 369-375
Subcellular Distribution and Macromolecular Binding of Aflatoxin in Fetal and Neonatal Rat Liver....Pages 377-387
The Immunosuppressive Action of Gliotoxin and Related Epipolythiodioxopipderazines....Pages 389-393
Cellular Effects of Cytochalasins....Pages 395-402
Selective Antitumor Activity of T-2 Toxin-Antibody Conjugates....Pages 403-409
Effects of Cyclopiazonic Acid: Guinea Pig Skeletal Muscle....Pages 411-425
Immunoglobulin a Nephropathy as a Manifestation of Vomitoxin (Deoxynivalenol) Immunotoxicity....Pages 427-440
Front Matter....Pages 247-247
Combined Cyclopiazonic Acid and Aflatoxin B 1 Effects on Serum Bacteriostasis, Complement Activity, Glycocholic Acid, and Enzymes and Histopathologic Changes in Guinea Pigs....Pages 441-449
Mycotoxin-Induced Alterations in Ion Transport Across Cell Membranes....Pages 451-465
Biotransformation of Trichothecenes: The Role of Intestinal Microflora in the Metabolism and Toxicity of Trichothecene Mycotoxins....Pages 467-481
Deregulation of c-myc Gene and Modulation of Glucocorticoid Receptor by Aflatoxin B 1 ....Pages 483-488
Selective Effects of T-2 Toxin and Ochratoxin a on Immune Functions....Pages 489-495
Emestrin, a New Mycotoxin, Introduced Injuries in Various Organs of Mice....Pages 497-504
The Molecular Mechanism of Toxicity of Gliotoxin and Related Epipolythiodioxopiperazines....Pages 505-512
Activation and Specificity of Aflatoxin B 1 Binding on hhc M , a Human Oncogene of Low Efficiency, and Cell Transformation....Pages 513-527
Front Matter....Pages 529-529
Algal Toxins: General Overview....Pages 531-544
The Polyether Brevetoxins and Site Five of the Voltage-Sensitive Sodium Channel....Pages 545-551
Cellular Mechanisms of Action for Freshwater Cyanobacteria (Blue-Green Algae) Toxins....Pages 553-573
New Aspects of Tetrodotoxin....Pages 575-588
Polyether Toxins Implicated in Ciguatera and Seafood Poisoning....Pages 589-596
The Cellular Mechanism of Action of Maitotoxin and Ciguatoxin....Pages 597-603
Recent Progress in the Chemistry and Toxicology of Paralytic Shellfish Poisoning....Pages 605-610
Back Matter....Pages 611-617