Medicinal Chemistry Advances. Proceedings of the Seventh International Symposium on Medicinal Chemistry, Torremolinos, Spain 2–5 September 1980

Content: 
Other Pergamon Titles of Related Interest, Page ii
Front Matter, Page iii
Copyright, Page iv
List of Contributors, Pages ix-xii
Introduction, Page xiii, R. Madroñero, F.G. De Las Heras, S. Vega
Current Options in Drug Design, Pages 1-10, A. Burger
Medicinal Chemistry and Current Problems in Drug Development, Pages 11-26, F.P. Doyle
2′-Fluoro-arabinosyl Pyrimidine Nucleosides: Chemistry, Antiviral, and Potential Anticancer Activities, Pages 27-40, J.J. Fox, C. Lopez, K.A. Watanabe
Nucleoside Antibiotics. Mode of Action, Pages 41-53, D. Vázquez
Antitumor and Antiviral Activity of N6-Hydroxyadenine Nucleosides and Related Derivatives, Pages 55-67, A. Giner-Sorolla, J.H. Burchenal, C. Lopez
Alkylating Nucleosides, Pages 69-83, M.T. García-López, F.G. de las Heras
Molecular Engineering: A General Approach to QSAR, Pages 85-96, R. Carbo, C. Arnau
Towards More Realistic Computer Simulations in Theoretical Molecular Biology, Pages 97-102, E. Clementi
AB Initio Quantum Chemical Approach to the Antibiotic Activity of β-Lactams, Pages 103-116, C. Petrongolo, G. Ranghino, R. Scordamaglia
Cyclic Analogues of Agonists as a Tool for Structure-Activity Relationships, Pages 117-129, G. Lambrecht, E. Mutschler
Thromboxane A2 and Atherosclerosis, Pages 131-140, F. Numano
Biological Activities of Some Metabolites and Analogues of Prostacyclin, Pages 141-158, B.J.R. Whittle, S. Moncada, J.R. Vane
The Role of Platelet Inhibitors in Degenerative Vascular Diseases, Pages 159-164, G. deStevens
Thromboxane-Dependent Platelet Aggregation: Role and Limitations, Pages 165-169, B.B. Vargaftig, M. Chignard, J.P. Le Couedic, J. Benveniste
Pharmacological and Biochemical Studies on Benzodiazepines, Pages 171-178, S. Garattini, S. Caccia, T. Mennini
Receptor Mapping, Pages 179-190, L.G. Humber
Multiple Analgesic Receptors, Pages 191-209, P.D. Garcia de Jalón, F. Pelayo
New Approaches to Antiviral Agents, Pages 211-224, L. Carrasco, C. Fernández-Puentes, M.A. Alonso, J.C. Lacal, A. Muñoz, J.M. Fernández-Sousa, D. Vázquez
New Antiviral Agents: Some Recent Developments, Pages 225-238, D. Shugar
Chemical Control of Oncogenic Events by RNA Tumor Viruses, Pages 239-258, P. Chandra
General Mechanisms of Action of Hypolipidemic Agents, Pages 259-269, F. Grande
Central Mechanisms of Anorectic Drugs, Pages 271-282, R. Samanin
Antiobesity Agents Acting Through Peripheral Mechanisms, Pages 283-297, A.C. Sullivan, J. Triscari, K. Comai
Agents Acting on Mucociliary System, Pages 299-315, A. Giráldez
Adrenergic and Anticholinergic Bronchodilators; Do They Act as Bronchospasmolytics? Perspectives in the development of anti-asthmatics, Pages 317-328, E.J. Ariëns
Agents Acting on the Immunological Component in Respiratory Diseases, Pages 329-343, J.W.F. Wasley
Present Knowledge of GABA Receptor Agonists, Pages 345-353, G. Bartholini
New Trends in Minor Tranquilizers, Pages 355-368, E. Kyburz
Trans-N-Alkyl-6, 7-Dihydroxyoctahydrobenzo[g]-Quinolines: Apomorphine Congeners Lacking the Non-Oxygenated Aromatic Ring, Pages 369-381, J.G. Cannon, J.A. Beres, T. Lee, J.P. Long
Dopamine Receptor Blockade by Substitute Benzamide Drugs, Pages 383-396, D.J. Roberts
Target Enzyme-Activated Irreversible Enzyme Inhibitors, Pages 397-409, B.W. Metcalf
Proteolytic Enzyme Inhibitors, Pages 411-422, H. Tschesche
Sialidases and Their Inhibitors, Pages 423-434, R. Schauer, A.P. Corfield
Inhibitors of Cyclic Nucleotide Phosphodiesterases, Pages 435-445, J.C. Stoclet, C. Lugnier
The Systematics of Bioactive Peptide Structure-Activity Relationships, Pages 447-459, J.S. Morley
Chemical and Biological Properties of Beta-Lipotropin and Endorphins: Metabolism and Mechanisms of Inactivation, Pages 461-472, M.M. Puig
Neurohypophysial Hormones and Neurophysins: Structures, Precursors and Evolution, Pages 473-485, R. Acher, J. Chauvet, M.T. Chauvet
Relations Between the Structure and Biological Activity of Insulin, Pages 487-502, D. Brandenburg
Index, Pages 503-512