Medical Toxicology: Proceedings of the 1991 EUROTOX Congress Meeting Held in Masstricht, September 1 – 4, 1991

Front Matter....Pages I-VIII
Front Matter....Pages 1-1
Medical Toxicology in Europe: Present and Future....Pages 3-11
Medical Toxicology — Clinical aspects....Pages 12-19
Research Aspects in Clinical Toxicology....Pages 20-25
Front Matter....Pages 27-27
Diagnosis in Clinical Toxicology....Pages 29-39
Haemoperfusion, Indications and Side-Effects....Pages 40-49
Accidental Poisoning with Hydrocarbon Products in Children During Six Months 1989....Pages 50-53
Clinical Neuropsychological Assessment of Patients Chronically Exposed to Organic Solvents....Pages 54-57
Front Matter....Pages 59-59
Risk Assessment — Scientific Aspects....Pages 61-72
Industrial Aspects of Risk Assessment....Pages 73-74
Risk Assessment: Governmental Aspects....Pages 75-82
Communicating About Toxicological Risks....Pages 83-93
Front Matter....Pages 95-95
Health Risk Assessment of Long Term Exposure to Chemicals: Application to Cadmium and Manganese....Pages 97-102
Animal Studies for Prediction of Chronic Toxicity....Pages 103-112
Toxicological Evaluation of Dimethomorph: Basis for Assessment of Risks from Dietary Exposure....Pages 113-116
Chronic Exposure to Vanadate as Factor of Arterial Hypertension in the Rat: Toxicodynamic Mechanisms....Pages 117-120
Front Matter....Pages 121-121
Dermal Toxicology....Pages 123-129
Cycads, Designer Drugs, Free Radicals and Neurodegenerative Disease....Pages 130-139
Electrophysiological and Flow Cytometric Studies on Mechanism of Gentamicin Nephrotoxicity in Cultured Renal Cells....Pages 140-143
Selective Cellular Toxicity After Exposure to 4-Ipomeanol, Bromobenzene (BrBz) and 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK) in Rat Lungs....Pages 144-147
Front Matter....Pages 149-149
Decreased Hepatic Phosphoenolpyruvate Carboxykinase Gene Expression after 2,3,7,8-Tetrachlorodibenzo- p -dioxin Treatment: Implications for the Acute Toxicity of Chlorinated Dibenzo- p -dioxins in the Rat....Pages 151-155
Front Matter....Pages 149-149
Co-Cultures of Rat Hepatocytes in the Study of Valproate Toxicity....Pages 156-159
Selenium-Silver Interaction in Mice....Pages 160-163
Front Matter....Pages 165-165
Environmental Impact on Domestic and Wild Animals: Field Data from a Veterinary Anti-Poison Center....Pages 167-171
Blood Mercury and Serum Selenium Concentrations in Reindeer Herders in the Arctic Area of Northern Finland....Pages 172-175
Front Matter....Pages 177-177
Natural Syndromes in Dogs....Pages 179-186
Inducible thyroid lesions in the rat with special reference to mediation or interactions with other organ systems....Pages 187-196
Mesulergine Induced Leydig Cell Tumours, a Syndrome Involving the Pituitary-Testicular Axis of the Rat....Pages 197-204
Variations in Prevalence of Endocrine Tumors Among Different Colonies of Rats? A Retrospective Study in the Hannover Registry Data Base....Pages 205-214
Front Matter....Pages 215-215
Biologically Based Modeling in Toxicology Research....Pages 217-227
QSAR Studies in Genetic Toxicology: Congeneric and Non Congeneric Chemicals....Pages 228-237
Quantitative and Qualitative Structure Activity Relationships in Developmental Toxicity....Pages 238-248
Multi-Compartment Model to Study the Effect of Air-Blood and Blood-Tissue Partition Coefficients on Concentration-Time-Effect Relationships....Pages 249-252
Concepts for Toxicokinetic-Toxicodynamic Modelling in Clinical Toxicology: Application to Acute Cardiac Glycoside Intoxications....Pages 253-256
Front Matter....Pages 257-257
Analytical Forensic Toxicology....Pages 259-267
Biological Effect Monitoring....Pages 268-277
Biological Monitoring of Exposure to Bitumen Fumes During Road Paving Operations....Pages 278-281
Toxicological Investigations on Unusual Materials (Hair and Vitreous Humor): Interest and Limitations....Pages 282-285
Front Matter....Pages 287-287
Ethylene Oxide: Metabolism in Human Blood and Its Implication to Biological Monitoring....Pages 289-289
Back Matter....Pages 291-291