Maturation Phenomenon in Cerebral Ischemia IV: Apoptosis and/or Necrosis, Neuronal Recovery vs. Death, and Protection Against Infarction

Front Matter....Pages I-XVI
Front Matter....Pages 1-1
A Role for the Gtpase Pathway in Neuronal Damage after Cerebral Ischemia: The Impact of the DNA Array Technique on Stroke Research....Pages 3-9
Induction of Hypoxia-Inducible Factor-1 (HIF-1) in Adult and Neonatal Rat Brain: Possible Relationship to Hypoxia-induced Tolerance to Ischemia....Pages 11-17
Characterization of the elF2-Associated Protein p67 During Brain Ischemia and Reperfusion....Pages 19-23
Is DNA Methylation Deleterious in Cerebral Ischemia?....Pages 25-33
Distinct Ischemic Effects on HSC70, HSP72, and c-fos Expression in Young and Adult Gerbils....Pages 35-40
Bcl-w Expression and Localization in Brain Ischemia....Pages 43-48
Front Matter....Pages 49-49
Thrombosis After Ischemic Stroke-Platelet Aggregation....Pages 51-59
The Role of the Immunophilin FKBP12 in Cerebral Ischemia....Pages 61-69
Localization of Macrophage Migration Inhibitory Factor in the Brain Following Focal Cerebral Ischemia in the Rat....Pages 71-75
Environmental Influence on Neuronal and Dendritic Spine Plasticity After Permanent Focal Brain Ischemia....Pages 77-83
Relationship Between DNA Fragmentation, Energy State, and Protein Synthesis After Transient Focal Cerebral Ischemia in Mice....Pages 85-91
Changes in Postsynaptic Densities After Brain Ischemia....Pages 93-101
Functional Plasticity of the Brain After Ischemic Injury Assessed by Near Infrared Topography....Pages 103-110
Front Matter....Pages 111-111
TNF- a and Ceramide as Mediators of Neuronal Tolerance to Brain Ischemia....Pages 113-121
Upregulation of Transforming Growth Factor-Beta 1 Expression in Rat Hippocampal Neurons After Transient Forebrain Ischemia and After β 2 -Adrenoceptor Stimulation....Pages 123-133
Bcl-2-Protein Is Upregulated After Chemical Induction of Ischemic Tolerance Using 3-Nitropropionic Acid in Rats....Pages 135-139
Time Course of Postischemic Stroke Symptoms and Delayed Infarction After Transient Cerebral Ischemia in Gerbils: Effect of Chemical Preconditioning Using 3-Nitropropionic Acid....Pages 141-145
Cyclic AMP Response Element Binding Protein Phosphorylation May Be Closely Associated with Neuroprotective Mechanisms After Focal Ischemia in Rat Brain....Pages 147-155
Recent Evidence on the Neuroprotective Effects of Pituitary Adenylate Cydase-Activating Polypeptide....Pages 157-164
Evolution of Microcirculatory Derangement in Focal Ischemic Penumbra Following Pial Arteriolar Occlusion as Observed by the Novel Photoelectric Method....Pages 165-170
Front Matter....Pages 171-171
Delayed Maturation of Cortical Infarction: Role of Caspasesand NF- K B-Mediated Transcription....Pages 173-180
Cellular Components with Adaptive Responses Contributing to Expansion and Repair Process of Ischemic Brain Damages Caused by Major Vessel Occlusion....Pages 181-187
Combination Drug Therapy and Mild Hypothermia: Comparison with Neurosurgical Standard Regimen in a Rat Model of Reversible Focal Cerebral Ischemia....Pages 189-203
Thrombolysis in Acute Stroke....Pages 205-209
Front Matter....Pages 211-211
Cytochrome c Is Released from the Mitochondria of Vulnerable Hippocampal CA 1 Neurons in Rats After Transient Global Cerebral Ischemia....Pages 213-221
Formation of 4-Hydroxy-2-Nonenal-Modified Proteins in the Rat Brain Following Transient Global Ischemia Induced by Cardiac Arrest and Resuscitation....Pages 223-227
Mitochondrial Dysfunction and Maturation of Brain Damage After Transient Ischemia....Pages 229-239
Hypoxia-lnduced DNA Damage in the Rat Brain....Pages 241-251
Ultrastructure and Morphometry of Astroglial Mitochondria Following Temporary Ischemia....Pages 253-258
Front Matter....Pages 261-261
Translating Experimental Stroke Research into the Clinical Arena....Pages 263-278
Back Matter....Pages 281-284