LH-RH and its Analogues: Fertility and Antifertility Aspects

Opening remarks
Opening remarks
Contents
Physiological basis for clinical use of LH-RH and its analogues
Hypothalamic control of gonadotropin secretion and ovarian function
Induction of ovulation in amenorrhea infertile women with pulsatile administration of gonadotropin releasing hormone
Effects of different substituents in the A-ring of estradiol on its potency in sensitizing pituicytes to gonadotropin releasing hormone
Present status of LH-RH analog chemistry
Pharmacology of GnRH analogues
Binding sites for LH-RH in the human — does LH-RH exert extrapituitary actions in man?
Influence of LH-RH and des-Gly10 [D-Ala6]-LH-RH ethylamide on the biosynthesis of hCG in placental tissue culture
The pharmacologic profile of [(ImBzl)-D-His6,Pro9-NEt]-LH-RH (ORF 17070), an LH-RH agonist
Reversible pharmacologic castration of the female: implications for endometriosis, contraception and ovulation induction
Metabolism and pharmacokinetics of LH-RH agonists
Studies on controlled release systems for LH-RH analogues
Comparative reproductive pharmacology of LH-RH agonist and antagonist: contraceptive, therapeutic and safety aspects
Comparative non-human primate studies with LH-RH analogues
Long-term suppression of ovulation in the stumptailes macaque by active immunization against LH-RH or by LH-RH agonist administration
LH-RH agonists in the male: basic and clinical studies
A new approach to male contraception using combined androgen and GnRH analog treatment
LH-RH analog therapy of precocious puberty
Treatment of prostatic cancer with LH-RH analogues and control of therapy by cytology and DNA cytophotometry
Clinical experience (up to 40 months) with the LH-RH agonist Buserelin in the therapeutic approach to prostatic cancer
Antigonadal properties of LH-RH agonists: therapeutical applications in human
Contraceptive use of LH-RH agonists
LH-RH analogs and luteal function of the rhesus monkey
The effects of an LH-RH agonist on the premenstrual syndrome: a preliminary report
Discontinous intranasal application of the LH-RH analogon Buserelin in combination with an oral progestin in healthy female volunteers
Reversible down-regulation of pituitary-ovarian function induced by repetitive LH-RH agonist administration as a new approach for treatment and study of endometriosis in the human
The treatment of endometriosis with LH-RH agonists
Concluding remarks
List of First-mentioned Contributors