Late Sequelae in Oncology

Front Matter....Pages I-XI
Front Matter....Pages 1-1
Impact of Endogenous and Exogenous Factors on Radiation Sequelae....Pages 3-12
Endogenous and Exogenous Factors Modifying Chemosensitivity to Cytostatic Drugs....Pages 13-19
Front Matter....Pages 21-21
Radiation-Induced Injury of the Central Nervous System....Pages 23-27
Cytostatic-Induced Central Nervous System Abnormalities....Pages 29-34
Radiation Myelopathy....Pages 35-42
Acute and Late Toxicity on Peripheral Nerves After Radiotherapy....Pages 43-49
Acute and Late Toxicity on Peripheral Nerves After Chemotherapy — A Review....Pages 51-58
Endocrine Dysfunction After Brain Tumor Therapy in Children....Pages 59-64
Endocrine Dysfunction in Adults After Radiotherapy for Pituitary Adenomas and Suprasellar Tumors....Pages 65-71
Late Sequelae Affecting the Ear....Pages 73-79
Ototoxicity in Pediatric Oncology....Pages 81-86
Front Matter....Pages 87-87
Biological Basis for Skin and Mucosal Toxicity....Pages 89-91
Radiation-Induced Fibrosis: Experimental Studies....Pages 93-97
Lymphedema of the Arm After Treatment of Breast Cancer....Pages 99-104
Skin and Mucosal Damage After Radiotherapy for Head and Neck Tumors....Pages 105-110
Mucosal Toxicity After Radiochemotherapy....Pages 111-119
Complications of the Small Intestine and the Pancreas After Intraoperative Radiotherapy....Pages 121-126
Skin Toxicity....Pages 127-131
Front Matter....Pages 133-133
Radiation Pneumopathy — Experimental and Clinical Data....Pages 135-140
Lung Toxicity of Chemotherapeutic Agents....Pages 141-149
Front Matter....Pages 133-133
Differential Diagnosis of Treatment Sequelae in the Lung....Pages 151-159
Front Matter....Pages 161-161
Evaluation of Late Cardiotoxicity by Pulsed Doppler Echocardiography in Patients Treated for Hodgkin’s Disease....Pages 163-173
Anthracycline-Induced Cardiotoxicity in Children: Pathophysiology and Prevention....Pages 175-180
Radiation-Induced Cardiotoxicity: Experimental Data....Pages 181-189
Cardiotoxicity After Megavoltage Irradiation and Chemotherapy for Hodgkin’s Disease with Special Emphasis on Coronary Heart Disease Mortality — The Freiburg Experience 1940–1992....Pages 191-195
Cardiac Morbidity and Mortality Following Radiotherapy....Pages 197-203
Front Matter....Pages 205-205
Nephrotoxicity of Ifosfamide in Children....Pages 207-213
Radiation Nephritis....Pages 215-224
Front Matter....Pages 225-225
Long-Term Gonadal Dysfunction and Its Impact on Bone Mineralization in Patients Following COPP/ABVD Chemotherapy for Hodgkin’s Disease....Pages 227-233
Gonadal Dysfunction After Radiotherapy....Pages 235-242
Front Matter....Pages 243-243
Dose-Time Considerations for Skeletal Growth Disturbances After Radiotherapy....Pages 245-250
Disturbances in Growth of Bone, Muscle, and Fat Tissue Following Irradiation in Childhood....Pages 251-253
Growth Failure Secondary to Radiotherapy of Brain Tumors in Childhood....Pages 255-260
Front Matter....Pages 261-261
Experiments on the Carcinogenic Potential of Antineoplastic Agents....Pages 263-271
Secondary Malignancies Following Cytotoxic Chemotherapy....Pages 273-277
Secondary Malignancies After Radiotherapy....Pages 279-289
Back Matter....Pages 291-300