Kinins V

Front Matter....Pages i-xxvi
Tissue Kallikreins and Kinins: Roles in Human Disease and Target for New Drug Development....Pages 1-6
Control of Kininogen Gene Expression....Pages 7-18
Biochemistry of Renin....Pages 19-24
Angiotensin I Converting Enzyme....Pages 25-28
Pharmacokinetics of Angiotensin Converting Enzyme Inhibitors in Plasma and Tissue Using Radioinhibitor Binding and Displacement Assays....Pages 29-34
Role of the Endogenous Angiotensin II in the Antihypertensive Effect of MK 421 in Rats made Hypertensive by Norepinephrine or Vasopressin....Pages 35-38
Significance of Kallikrein-Kinin and Renin-Angiotensin Systems in the Hypotensive Mechanism of Angiotensin-I Converting Enzyme Inhibitors in Essential Hypertensives....Pages 39-48
Clinical Usefulness of Low-Dose Captopril on Mild to Moderate Essential Hypertension....Pages 49-53
Therapeutic Regime of Enalapril Maleate in Japan....Pages 55-61
Beneficial and Adverse Effects of Angiotensin Converting Enzyme Inhibitors....Pages 63-71
Structural Analysis of a Rat Renal Kallikrein Gene....Pages 73-80
Development of Competitive Antagonists of Bradykinin....Pages 81-86
Physiological Role of Renal Kallikrein-Kinin System in Human....Pages 87-96
Effects of Kinin on Electrolytes Transport and Regulation of Kininase Activity in Distal Nephron Segments of the Rat....Pages 97-104
Diversity of Kinin Effects on Transporting Epithelia....Pages 105-111
The Role of T-Kininogen and H and L Kininogens in Health and Disease....Pages 113-116
Recent Studies on the Rule of Kinins in Inflammatory Diseases of Human Airways....Pages 117-123
The Kallikrein-Kinin System in Inflammation....Pages 125-136
A Significant Role of Plasma Kallikrein-Kinin System in Plasma Exudation of Rat Carrageenin-Induced Pleurisy....Pages 137-144
Role of High Molecular Weight (HMW)-Kininogen in Inflammatory Exudation: Evidence With the Studies of the Hmw-Kininogen Deficient Rat....Pages 145-152
Kallikrein-Kinin System in Infectious Diseases....Pages 153-157
Kininogen in Tumor-Bearing Mice....Pages 159-168
Regional Distribution of Angiotensin Converting Enzyme in the Rat Kidney....Pages 169-174
Immunohistologic Characterization of Angiotensin Converting Enzyme in the Human Kidney Using Monoclonal and Polyclonal Antibodies....Pages 175-180
Effects of Mineralocorticoid on Kininase Activity Along the Distal Nephron Segments of the Rat....Pages 181-184
Selective Expression of Des-Arg 9 -Br Sensitive (Bi) Receptors in Vivo and in Vitro by Angiotensin Converting Enzyme Inhibitors....Pages 185-189
Demonstration of in Vivo Effects of ace Inhibitors by the use of Autoregressive Modelling....Pages 191-195
Contribution of Kinin System to the Antihypertensive Action of Angiotensin Converting Enzyme Inhibitors....Pages 197-205
Increased Insulin-Responsiveness by Ace-Inhibition in Non-Insulin Dependent Diabetes Mellitus....Pages 207-213
A New Structural Class of Biologically Active Peptide in Non-Mammals....Pages 215-220
Vasoactive Peptides from the Vespa Orientalis Hornet Venom....Pages 221-223
Bradykinin Analog Induce Histamine Release from Human Skin Mast Cells....Pages 225-229
Role of Cardiovascular Phospholipase A 2 and C in the Development of Doca-Salt Hypertensive Rats....Pages 231-236
Neutrophil Producing Capacity of 5-Lipoxygenase Metabolites of Arachidonic Acid After Major Surgery....Pages 237-242
The Mechanism of the Stimulatory Effect of Kallikrein on Prostacyclin Production in Vascular Endothelial Cells....Pages 243-247
The Effect of Bradykinin and its Fragments on the Arachidonate Cascade of Brain Microvessels....Pages 249-254
Mechanism of Bradykinin-Induced Nociceptive Response....Pages 255-259
Antagonism of the Algesic Action of Bradykinin on the Human Blister Base....Pages 261-268
Effects of Sodium Intake on Urinary Excretion and Renal Content of Bradykinin and its Metabolites in Rats....Pages 269-274
Kallikrein Release by Rat Kidney Slices : Effect of Norepinephrine....Pages 275-279
Relationship Between anp, Cyclic GMP and Tissue Kallikrein Following Saline Infusion in Healthy Volunteers....Pages 281-286
Bradykinin (BK) Enhances Diuresis and Natriuresis in Saline Volume-Expanded Dogs....Pages 287-291
Kininase Activities in the Human Pituitary Gland....Pages 293-298
Purification of Human Seminal Plasma Kininase II Using Affinity Chromatography....Pages 299-303
Dipeptidyl(Amino)Peptidase IV and Post Proline Cleaving Enzyme in Cultured Endothelial and Smooth Muscle Cells....Pages 305-311
Isolation and Study of the Properties of Kininase from the Venom of Spider Latrodectus Tredecimguttatus....Pages 313-318
Post Synthetic Modification of CK-MM by Kininase I....Pages 319-324
Structure of Human Carboxypeptidase N (Kininase I)....Pages 325-329
The Mechanism of Degradation of Bradykinin (Lysyl-Bradykinin) in Human Serum....Pages 331-336
Rocket Immunoassay of High and Low Molecular Weight Kininogens in Human Plasma....Pages 337-343
High Molecular Weight Kininogen Binds to Neutrophils....Pages 345-348
Inhibition of Thrombin-Induced Platelet Aggregation by High Molecular Weight Kininogen....Pages 349-351
Characterization of Kinins Released from Human Kininogens by Human Urinary Kallikrein....Pages 353-357
Ornitho-Kininogen and Ornitho-Kinin: Isolation, Characterization and Chemical Structure....Pages 359-367
The Kallikrein-Kininogen System in Myocardial Infarction....Pages 369-373
The Pathophysiological Role of Kinin and Chemical Mediators on Experimental Allergic Rhinitis....Pages 375-378
Release of Kinin and other Chemical Mediators After Antigenic Stimulation in Allergic Rhinitis Patients....Pages 379-383
Kallikrein Activity in Saliva of Patients with Inflammatory and Hyperplastic Diseases of the Oral Mucous Membrane....Pages 385-387
The Effect of Cyclosporine on Urinary Kallikrein Excretion in Patients with Rheumatoid Arthritis....Pages 389-392
The Influence of Oxindanac on Kallikrein Metabolism....Pages 393-397
Basic Pharmacology of Kinins: Pharmacologic Receptors and other Mechanisms....Pages 399-407
An Iodinatable Photoaffinity Probe Based on the Structure of Kallidin....Pages 409-414
Specific Binding Sites for Bradykinin and its Degradation Process in Cultured Rat Vascular Smooth Muscle Cells....Pages 415-420
Kinin Receptors on Epithelial Cells and Smooth Muscle of the Trachea....Pages 421-427
Different Involvement of Endothelium-Derived Relaxing Factor and Prostacyclin in Vasodilator Response to Bradykinin in Isolated Dog Blood Vessels....Pages 429-434
The Effect of a Bradykinin Antagonist on Vasodilatation in the Cat and Rabbit....Pages 435-438
Effects on Blood Pressure of Intracerebroventricular Administration of a Kinin Antagonist....Pages 439-445
Hageman Factor Dependent Kinin Generation System in Guinea Pig Skin: Extravascular Localization of the Components, and Prolonged Vascular Reaction in Inhibitor-Depleted Animal of this System....Pages 447-452
Hageman Factor Activation by Polysaccharides: Effect of Molecular Weight....Pages 453-460
Some Cardiovascular and Hematological Changes Induced in the Rat by Activation of Hageman Factor with Ellagic Acid....Pages 461-465
Isolation and Characterization of Plant Inhibitors Directed Against Plasma Kallikrein and Factor XII....Pages 467-471
A Monoclonal Antibody Recognizing an Iscosapeptide Sequence in the Heavy Chain of Human Factor XII Inhibits Surface-Catalyzed Activation....Pages 473-476
Effects of Intravascular Ionic and Non-Ionic Radiographic Contrast Agents on Parameters of the Kallikrein-Kinin-System....Pages 477-480
Changes in Components of the KK-System After Recirculation and the Addition of Plasma Kallikrein....Pages 481-486
Degradation of Hageman Factor by Chymotrypsin-Like Protease Released from Rat Mast Cells During Degranulation....Pages 487-492
Kinin Release from Human LMW-Kininogen by the Cooperative Action of Human Plasma Kallikrein and Leukocyte Elastase....Pages 493-498
Binding of a Monoclonal Anti-Human Plasma Prekalliprein Antibody to the Complexes of Kallikrein with Cl-Inhibitor and α 2 -Macroglobulin Analyzed by Immunoblot and “Sandwich” Assays....Pages 499-505
Human Urinary Kallikreins A, B and D: Isolation, Purification and Properties....Pages 507-511
Human Urinary Prokallikrein -Structural Analysis on Activation Mechanism....Pages 513-518
Human Urinary Kallikrein: Amino Acid Sequence and Carbohydrate Attachment Sites....Pages 519-525
Structural Analysis of ASN-Linked Oligosaccharides of Porcine Pancreatic Kallikrein....Pages 527-532
Fast Atom Bombardment Mass Spectrometry (FAB-MS): Analysis of Complex Carbohydrate Chains of Tissue Kallikreins....Pages 533-538
Isolation of [Hydroxyproline 3 ]Lysyl-Bradykinin Formed By Kallikrein from Human Plasma Protein....Pages 539-544
Tissue Kallikrein Effectively Activates Latent Matrix Degrading Metalloenzymes....Pages 545-548
A Micro-Kininogenase Assay for Studies of Kallikrein in Renal Micropuncture/Microperfusion....Pages 549-554
Exercise-Induced Increase in Glandular Kallikrein Activity in Human Plasma and its Significance in Peripheral Glucose Metabolism....Pages 555-562
Kallikrein-Induced Rat Uterus Contraction is Dependent on Kinin Release....Pages 563-566
Relationship Between Human Seminal Kallikrein-Kinin System and Spermatogenesis....Pages 567-572
Tonin and Kallikrein-Kinin System....Pages 573-580
Bradykinin Infusion in Long Term Postoperative Parenteral Nutrition Improves Nitrogen Balance and Protein Synthesis....Pages 581-585
Quantification, Isolation and Structural Determination of Bradykinin and Hydroxyprolyl-Bradykinin in Tumor Ascites....Pages 587-592
Studies on Kallikrein-Kinin System and Enzymes Activity in Organs and Urine from Diabetic Mice Models....Pages 593-597
Serum Kininases I and II in Patients with Extrinsic and Intrinsic Asthma....Pages 599-602
Dose — Dependent Effects of Bradykinin Infusion in Postoperative Patients....Pages 603-608
Evidence for Multiple Functions of T-Lymphocytes Associated Serine Proteinases....Pages 609-613
Components of the Plasma Defense Systems in Intensive Care Patients with and with Without ARDS....Pages 615-620
Interrelationship Between Urinary Kallikrein and Arginine-Vasopressin in Man....Pages 621-627
Attenuation of Atrial Natriuretic Peptide by Kallikrein in Taurine Administered Rats....Pages 629-634
Mechanism of Taurine Natriuresis in Rats....Pages 635-640
Interaction of Atrial Natriuretic Peptide and Amiloride on the Renal Kallikrein-Kinin System....Pages 641-645
Opposite Effects on Kallikrein Excretion of Natriuretic Doses of Angiotensin Infused into the Dog and the Rat: Reversal of the Effect in the Rat by Atrial Natriuretic Peptide....Pages 647-652
Back Matter....Pages 653-662