Jan Gösta Waldenström and His World : The Life and Work of a Giant in Science, Medicine and Humanity

Foreword by Robert A. Kyle
Foreword by Giampaolo Merlini
Preface
	References
Acknowledgements
Contents
1 A Family of Pioneers
	References
2 Childhood in Stockholm and Student Years in Uppsala
	References
3 The Red Urine Story
	3.1 A Diagnostic Triumph
	3.2 The First Publication
	3.3 Hans Fischer in Munich
	3.4 In Munich with a Rockefeller Stipend
	3.5 Back in Sweden
	3.6 The Doctoral Thesis
	References
4 Letters to a Special Friend
	Reference
5 Assistant Professor in Uppsala
	5.1 Early Hematology Research
	5.2 The Growing Family
	References
6 Two New Diseases
	6.1 Uppsala, A Mecca of Physical Chemistry
	6.2 The Svedberg and the Ultracentrifuge
	6.3 Electrophoresis and Arne Tiselius
	6.4 Purpura Hyperglobilinemia
	6.5 Macroglobulinemia
	References
7 Exploring Medical Science in Wartime America
	7.1 Through Mined Waters to New York City
	7.2 Exploring Science in New York City
	7.3 Boston, “The Medical Capital of America”
	7.4 Washington University in St. Louis
	7.5 The University of Minnesota in Minneapolis
	7.6 The Mayo Clinic in Rochester
	7.7 Final Comments
	References
8 Turbulent Final Years in Uppsala
	8.1 Selecting a New Professor and Chairman
	8.2 The Winner in Uppsala
	8.3 The “Looser”
	References
9 “The Great Faculty” in Lund
	9.1 Introduction
	9.2 Pathology and Bacteriology
	9.3 Anatomy and Histology
	9.4 Physiology, Medical Chemistry, and Pharmacology
	9.5 The Department of Medicine
	References
10 Malmö General Hospital—MAS
	10.1 The Early Years
	10.2 The Next Generation
	10.3 Medicine
	References
11 Arrival in Malmö
	11.1 The Department of Medicine
	11.2 Department of Surgery
	11.3 Obstetrics and Gynecology
	11.4 Orthopedic Surgery
	11.5 Pathology and Bacteriology
	References
12 Autoimmune Hepatitis
	12.1 The German Society for Digestive and Metabolic Diseases—DGVS
	12.2 The 15th Congress of the DGVS
	12.3 A New Liver Disease
	References
13 A Charismatic Leader
	13.1 The Commander-in-Chief
	13.2 The Early Team
	13.3 New Routines
	13.4 Exciting the Medical Students
	References
14 The Carcinoid Syndrome
	14.1 The Discovery
	14.2 Intestinal Carcinoid
	14.3 A Meeting in Malmö
	14.4 Clinical Features
	14.5 From Bedside to the Bench
	14.6 Recent Contributions in the Carcinoid Syndrome
	References
15 Beginning of a Golden Age
	15.1 The New Wing
	15.2 Radiology
	15.3 Pathology
	15.4 The First Ph.D. Students
	15.5 Private Life
	References
16 Gammopathies—Jewel in the Crown
	16.1 A New Family
	16.2 The Harvey Lecture “Gammopathies”
	16.3 Monoclonal and Polyclonal Gammopathy
	16.4 Epidemiology of Gammopathies
	16.5 The Värmland Study
	16.6 Genetics of Monoclonal IgM
	16.7 MGUS, SMM, and MM
	16.8 Familial Autoimmunity
	References
17 Porphyria Research from Malmö
	17.1 Introduction
	17.2 The Porphyrin Diseases as Inborn Errors of Metabolism
	17.3 Enter Birgitta Haeger-Aronsen
	17.4 Neuropsychiatry and Genetics of Porphyria
	17.5 Diabetes Insipidus
	17.6 Pathogenesis of Porphyria and Its Rational Therapy
	References
18 Inga Marie Nilsson—“The Queen of Coagulation”
	18.1 A Rising Star Getting Help from Stockholm
	18.2 Erik Jorpes
	18.3 The Doctoral Thesis of Inga Marie Nilsson
	18.4 Anti-hemophilic Globulin
	18.5 Early Use of Cohn Fraction I-0 (AHF) in Von Willebrand’s Disease
	18.6 Hemophilia in Sweden
	18.7 Professor of Coagulation Research
	18.8 Factor VIII Bypass with Activated Factor VII
	18.9 A Royal Bleeding Condition
	18.10 The Legacy
	References
19 Carl-Bertil Laurell and His Outstanding Laboratory of Clinical Chemistry
	19.1 Introduction
	19.2 Carl-Bertil Laurell in Uppsala
	19.3 Carl-Bertil Laurell in Lund
	19.4 Carl-Bertil Laurell Arrives in Malmö
	19.5 Alpha-1 Antitrypsin Deficiency
	References
20 The Division of Cardiology
	20.1 The Period 1950–8
	20.2 Bengt W. Johansson as Leader
	20.3 Concluding Comment
	References
21 Bengt Skanse and Endocrinology in Malmö
	21.1 Bengt Skanse
	21.2 Thyroid Diseases
	21.3 Other Contributions
	21.4 Aldosterone
	21.5 Continued Growth of Endocrinology
	21.6 The Tragedy
	21.7 Endocrinology After Bengt Skanse
	References
22 Hematology
	22.1 The International Society of Hematology
	22.2 Hematology Research in Malmö
	22.3 Concluding Remarks
	References
23 A Friendship with Bertel von Bonsdorff
	23.1 Bertel von Bonsdorff
	23.2 All Light Comes From the East
	23.3 The Friendship and the Letters
	23.4 The Bertel von Bonsdorff Festschrift in 1964
	23.5 The Jan Waldenström Festschrift in 1966
	23.6 ISA, The International Society of Amyloidosis
	References
24 Visitors and Visits
	24.1 Introduction
	24.2 VIIth International Congress of Internal Medicine 1962
	24.3 Partners in Progress
	24.4 Visitors to Malmö
	24.5 Two Very Special Visitors
	References
25 The Nobel Symposium on Gamma Globulins
	25.1 Nobel Symposia
	25.2 The First Day: Structure of Gamma Globulins
	25.3 Day 2. Structure and Heterogeneity of Gamma Globulins
	25.4 Day 3. A Visit to Uppsala
	25.5 Day 4. Control of Biosynthesis
	25.6 Days 4–5. Clinical Aspects on Control of Gamma Globulin Synthesis
	25.7 The Take Home Message
	References
26 Emeritus Professor of Medicine
	26.1 The Farewell Lecture
	26.2 JW’s Private Practice
	26.3 Editor of Acta Medica Scandinavica
	References
27 New Activities in Stockholm
	27.1 Skandia International Symposia
	27.2 Radiumhemmet, Jerzy Einhorn, and Oncology in Sweden
	27.3 The THX Doctor
	References
28 Jan Waldenström. An Esteemed Globetrotter
	28.1 A Popular Visitor
	28.2 The Jahre Prize
	28.3 Other Honors
	28.4 Fogarty Scholar at NIH in 1978
	28.5 At Home
	28.6 Concluding Remark
	References
29 Macroglobulinemia—An Update
	29.1 1984—The 40th Anniversary
	29.2 Significant News from the Bing Center for Waldenström’s Macroglobulinemia
	29.3 10th International Workshop on Waldenström’s Macroglobulinemia
	29.4 Macroglobulinemia Then and Now, a Success Story
	References
30 Happy Years
	30.1 A Man with Temperament
	30.2 JW More Private
	30.3 The 80th Birthday at Torup Castle
	References
31 The Final Years
	31.1 The Last Decade
	31.2 The Legacy
	References
Author Index