Human T Cell Clones: A New Approach to Immune Regulation

Front Matter....Pages i-xv
Front Matter....Pages 1-2
Molecular and Functional Analysis of the Human T Cell Antigen/MHC Receptor....Pages 3-14
The Murine T Cell Receptor....Pages 15-23
The Genes of the Murine T Cell Receptor....Pages 25-34
Molecular Studies of the Human T-Cell Antigen Receptor....Pages 35-46
Front Matter....Pages 47-47
Cloned HLA-D Genes: Characterisation and Approaches to Expression and Analysis of Function....Pages 49-57
SB-Specific CTL Clones Exhibit Functional Heterogeneity in their Susceptibility to Blocking by Anti-T3 and Anti-T4 Antibodies....Pages 59-69
Recognition of HLA class II Molecules by Functional Human T-Lymphocyte Clones (TLC’s)....Pages 71-82
Restriction Elements on Class II HLA Molecules Studied by Cloned Human T4 Cells....Pages 83-90
Molecular and Functional Analysis of HLA-Class II Molecules Responsible for the Primary MLR in Man....Pages 91-103
HLA-Class I Antigen Recognition by EB Virus-Specific and Allo-Specific Cytotoxic T Cells....Pages 105-114
Front Matter....Pages 115-116
Antigen Recognition by Human Influenza Virus Specific Helper T Lymphocyte Clones....Pages 117-124
Exogenous IL-2 Independent Antigen-Specific Human T Cells: Antigen-Specific Induction of Polyclonal B Cell Factors....Pages 125-133
Probing a repertoire of T cells responding to a mycobacterial antigen....Pages 135-145
Accessory Cell Requirements for the Proliferation of Antigen Specific Human T Cells....Pages 147-162
Nickel-Specific Human T Cell Clones: Functional Characterization and Requirements for Triggering....Pages 163-170
Front Matter....Pages 171-172
Human Lymphocyte Functional Antigens....Pages 173-185
Cell Surface Antigens Involved in Human Cytolytic T Lymphocyte-mediated Cytolysis....Pages 187-196
MHC-Restricted Antigen-Receptor Specific Regulatory T Cell Circuits in Man....Pages 197-208
Early Biochemical Events in T Lymphocytes Activated by Anti T3....Pages 209-217
Surface Structures Involved in Human Cytolytic T Lymphocyte Function....Pages 219-225
Front Matter....Pages 227-228
Manipulation of Autoimmune Diseases Using Autoimmune T Lymphocytes....Pages 229-237
Cloning of Autoimmune T Cells: Implications for Pathogenesis and Therapy....Pages 239-250
Self Education after Mismatched HLA Haploidentical Bone Marrow Transplantation....Pages 251-261
Human T-Cell Leukemia Viruses, T-Cell Leukemia and Aids....Pages 263-275
Front Matter....Pages 277-278
Autoregulation Of T-Cell Proliferation....Pages 279-284
Interleukin-2 Receptors....Pages 285-300
Response of T Cells to Synthetic Peptide Antigens: Specific Unresponsiveness Analogous to Tolerance....Pages 301-307
Antigen-T Lymphocyte Interactions in the Induction of Functional Unresponsiveness....Pages 309-315
Pathways and Mechanisms of Human T Cell Activation....Pages 317-325
Loss of Alloreactivity Associated with Acquired Suppressive and Natural Killer-Like Activities of Aged T Cell Clones....Pages 327-339
Phorbol Ester Induced Modulation of Lymphocyte Phenotype and Function....Pages 341-345
Front Matter....Pages 347-348
Regulation of growth and differentiation of human B cells....Pages 349-359
Antigen-Specific T Cell Helper Factors....Pages 361-368
Human T-Cell Hybrids Producing Antigen Specific Helper Factors....Pages 369-379
Influenza Specific Cytotoxic T-Cell Clones and Immune Interferon....Pages 381-388
The IL-1 Pathway in T Cell Activation....Pages 389-399
Front Matter....Pages 401-402
T Cell Clones Recognising Autologous Tumour Cells....Pages 403-410
Cell Surface Determinants Associated with the Interaction of Human CTL Clones and Autologous Tumor Cells....Pages 411-421
T3 − and T3 + Cloned Cytotoxic Lymphocytes: Functional and Phenotypic Characteristics....Pages 423-433
Murine and human tuberculin reactive T helper clones: their role in anti-tumour immunity....Pages 435-450
Back Matter....Pages 451-455