Human Neural Stem Cells: From Generation to Differentiation and Application

Front Matter ....Pages i-xi
Front Matter ....Pages 1-1
 Derivation of Neural Stem Cells from the Developing and Adult Human Brain  (Claire M. Kelly, Maeve A. Caldwell)....Pages 3-20
 Human Somatic Stem Cell Neural Differentiation Potential  (David J. Eve, Paul R. Sanberg, Leonora Buzanska, Anna Sarnowska, Krystyna Domanska-Janik)....Pages 21-87
 Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury  (Pavla Jendelova, Eva Sykova, Slaven Erceg)....Pages 89-102
 Generation of Human Neural Stem Cells by Direct Phenotypic Conversion  (Daekee Kwon, Hee-Jin Ahn, Kyung-Sun Kang)....Pages 103-121
Front Matter ....Pages 123-123
 Epigenetic Regulation of Human Neural Stem Cell Differentiation  (Mizuki Honda, Kinichi Nakashima, Sayako Katada)....Pages 125-136
 Induced Pluripotent Stem Cells Reveal Common Neurodevelopmental Genome Deprograming in Schizophrenia  (Sridhar T. Narla, Brandon Decker, Pinaki Sarder, Ewa K. Stachowiak, Michal K. Stachowiak)....Pages 137-162
 Genome Editing in Human Neural Stem and Progenitor Cells  (Raul Bardini Bressan, Steven M. Pollard)....Pages 163-182
 Brain Organoids: Expanding Our Understanding of Human Development and Disease  (L. B. Chuye, A. Dimitri, A. Desai, C. Handelmann, Y. Bae, P. Johari et al.)....Pages 183-206
 Bioengineering of the Human Neural Stem Cell Niche: A Regulatory Environment for Cell Fate and Potential Target for Neurotoxicity  (Leonora Buzanska, Marzena Zychowicz, Agnieszka Kinsner-Ovaskainen)....Pages 207-230
Front Matter ....Pages 231-231
 Updates on Human Neural Stem Cells: From Generation, Maintenance, and Differentiation to Applications in Spinal Cord Injury Research  (Yang D. Teng, Lei Wang, Xiang Zeng, Liquan Wu, Zafer Toktas, Serdar Kabatas et al.)....Pages 233-248
 Human Neural Stem Cells for Ischemic Stroke Treatment  (Zaal Kokaia, Vladimer Darsalia)....Pages 249-263
 Modeling Complex Neurological Diseases with Stem Cells: A Study of Bipolar Disorder  (Cameron D. Pernia, Neal H. Nathan, Brian T. D. Tobe, Alicia M. Winquist, Richard L. Sidman, Yoshio Goshima et al.)....Pages 265-282
 Neural Stem Cell Dysfunction in Human Brain Disorders  (Ewa Liszewska, Jacek Jaworski)....Pages 283-305
 Human Fetal Neural Stem Cells for Neurodegenerative Disease Treatment  (Daniela Ferrari, Maurizio Gelati, Daniela Celeste Profico, Angelo Luigi Vescovi)....Pages 307-329