Human Genetics: Problems and Approaches

Front Matter....Pages I-XXXVI
Introduction....Pages 1-9
History of Human Genetics....Pages 11-23
The Human Genome: Chromosomes....Pages 25-82
The Human Genome: Genes and DNA....Pages 83-127
Formal Genetics of Humans: Modes of Inheritance....Pages 129-162
Formal Genetics of Humans: Linkage Analysis and Gene Clusters....Pages 163-193
Formal Genetics of Humans: Multifactorial Inheritance and Common Diseases....Pages 195-256
Gene Action: Genetic Diseases....Pages 257-360
Gene Action: Developmental Genetics....Pages 361-383
Mutation: Spontaneous Mutation in Germ Cells....Pages 385-430
Mutation: Somatic Mutation, Cancer, and Aging....Pages 431-456
Mutation: Induction by Ionizing Radiation and Chemicals....Pages 457-493
Population Genetics: Description and Dynamics....Pages 495-548
Population Genetics: Consanguinity, Genetic Drift....Pages 549-582
Human Evolution....Pages 583-621
Behavioral Genetics: Research Strategies and Examples....Pages 623-691
Behavioral Genetics: Affective Disorders and Schizophrenia....Pages 693-704
Behavioral Genetics: Differences Between Populations....Pages 705-710
Genetic Counseling and Prenatal Diagnosis. Human Genome Project....Pages 711-732
Genetic Manipulations and the Biological Future of the Human Species....Pages 733-748
Back Matter....Pages 749-851