Host-Parasite Cellular and Molecular Interactions in Protozoal Infections

Front Matter....Pages I-XIX
Pattern of Variant Surface Glycoprotein Coating in Nascent Metacyclic Trypanosoma Brucei in the Salivary Glands of Glossina Morsitans....Pages 1-8
Evolution of Antigenic Variation in African Trypanosomes....Pages 9-18
Structural Studies on the Glycophospholipid Membrane Anchor of Trypanosoma Brucei Variant Surface Glycoprotein....Pages 19-28
Metabolism of Trypanothione and Glutathionylspermidine in Trypanosomatids....Pages 29-40
Differentiation of Trypanosoma brucei from Bloodstream to Procyclic Trypomastigotes....Pages 41-49
Digestive Enzymes, Receptor-Mediated Endocytosis and Their Role in the Nutrition of the Bloodstream-Form Trypanosome....Pages 51-65
The Cytoskeleton of Trypanosoma Brucei : Genes and Proteins....Pages 67-72
Genetic Re-Assortment of African Trypanosomes in Glossina ....Pages 73-78
Cell Surface Glycoproteins of Trypanosoma Cruzi....Pages 79-87
A Specific Inhibitor of Trypanosoma Cruzi Neuraminidase Found in Human Plasma....Pages 89-95
Definition of Trypanosoma Cruzi Antigens by Antibodies and T Cells....Pages 97-105
Molecular Pathogenicity of Leishmania in Intracellular Parasitism of Macrophages: Association of Virulent Phenotype with Increased Expression of a Major Membrane Glycoprotein and Microsomal N-Acetylglucosaminyl-Transferase....Pages 107-116
Infectivity of Leishmania Promastigotes is Dependent on the Expression of a 65,000 Dalton Surface Antigen....Pages 117-122
Characterization of Developmentally Regulated Molecules of Leishmania ....Pages 123-136
Leishmania Antigens Probed by Monoclonal Antibodies to Leishmania Membrane and to Acetylcholine Receptor....Pages 137-147
Structural Studies on Surface Glycoproteins of Leishmania Promastigotes: Isolation, Amino Acid Composition and Amino Terminal Sequence Studies....Pages 149-156
Membrane Attachment of the Major Surface Protein of Leishmania Promastigotes....Pages 157-163
The Promastigote Surface Protease of Leishmania....Pages 165-168
Acid Protease Activity of Leishmania gp63 and Its Possible Role in Virulence....Pages 169-173
The Roles of Surface Membrane Enzymes and Transporters in the Survival of Leishmania ....Pages 175-182
The Plasma Membrane H + -ATPase of Leishmania donovani Promastigotes....Pages 183-188
Phosphomonoesterases and Proteinases of Leishmanias....Pages 189-195
The Structure, Localization, and Function of the Lipophosphoglycan of Leishmania Donovani ....Pages 197-201
 Leishmania Host-Parasite Interactions : The Development of Chemotherapeutic Targets and Specific Drug Delivery Systems I. Lipoprotein Mediated Antileishmanial Chemotherapy....Pages 203-211
Recognition processes involved in binding and ingestion of L. donovani by host macrophages....Pages 213-221
Interaction of Leishmania and Membrane-Stabilizing Drugs with Human Phagocytic Cells....Pages 223-227
Suppression of Macrophage Accessory Functions by Leishmania Donovani ....Pages 229-233
Extracellular Development of Erythrocytic Malaria Parasites....Pages 235-244
The Relative Roles of N- And O-Linked Carbohydrate in the Invasion of Human Red Cells by Merozoites of Plasmodium Falciparum....Pages 245-254
Antigens of Plasmodium Falciparum Merozoites: Identification, Isolation and Functional Characterization....Pages 255-263
Studies on the Plasmodium Falciparum 195,000 Molecular Mass Merozoite Surface Antigen Precursor....Pages 265-274
Aspects of the Posttranslational Modification of a Major Plasmodium Falciparum Merozoite Surface Antigen....Pages 275-279
Export of Plasmodium Falciparum Proteins to the Host Erythrocyte Membrane: Special Problems of Protein Trafficking and Topogenesis....Pages 281-296
Inhibition of Knob Formation on Plasmodium Falciparum -Infected Erythrocytes by 2-Fluoro-L-Histidine....Pages 297-306
The Knob Protein Gene of Plasmodium Falciparum....Pages 307-314
Phosphoproteins Associated with the Host Erythrocyte Membrane during Plasmodium Chabaudi Infection....Pages 315-319
Malarial Sporozoite - Hepatocyte Interactions Mediating Invasion and Exoerythrocytic Development....Pages 321-327
Immuno-Electron Microscopic Observations on Plasmodium Falciparum Sporozoites Using Ultracryomicrotomy....Pages 329-334
Structural Homology of Membrane Proteins of Babesia Rodhaini....Pages 335-344
The Mechanism by which Interferon Gamma Blocks the Growth of Toxoplasma Gondii in Cultured Fibroblasts....Pages 345-354
Modification of Host Cell Phagocytic Compartments by Intracellular Toxoplasma Gondii ....Pages 355-364
Characterization of a 42 kDa Rhoptry Antigen of Toxoplasma Gondii ....Pages 365-369
 Entamoeba Histolytica : Activation and Release of Membrane Dense Bodies....Pages 371-376
 Entamoeba Histolytica : Effect of Bacterial Associates on Isoenzyme Patterns and Virulence....Pages 377-385
Trypanosomatid-Vector Interfaces - In Vitro Studies on Parasite Substrate Interactions....Pages 387-396
The Microecology of Leishmania in the Gut and Proboscis of the Sandfly....Pages 397-406
The Cellular and Molecular Interactions of Malaria Species with Their Mosquito Vectors....Pages 407-415
Concluding Remarks....Pages 416-418
Back Matter....Pages 419-427