Hormonal Control of the Hypothalamo-Pituitary-Gonadal Axis

Front Matter....Pages i-2
Role of Peptides in the Control of Gonadotropin Secretion....Pages 3-25
Molecular Aspects of the Release of Luteinizing Hormone Releasing Hormone (LHRH) from Hypothalamic Neurons....Pages 27-38
Role of Peptides in the Regulation of Gonadotropin and Prolactin Secretion....Pages 39-53
Estrous Cycle Dependent Modulation of Muscarinic Cholinergic Receptors in the Hypothalamus and Adenohypophysis....Pages 55-70
Hormones and other Messenger Molecules: An Approach to Unity....Pages 71-87
Regulation of the Synthesis, Release and Action of Hypothalamic Luteinizing Hormone Releasing Hormone....Pages 89-100
Degradation of LH-RH....Pages 101-114
Degradation of Luteinizing Hormone-Releasing Hormone by Rat Pituitary Plasma Membrane Associated Enzymes....Pages 115-126
GnRH Receptors: Identification, Localization and Implications for Biological Function....Pages 127-139
Physiological Regulation of Pituitary GnRH Receptors....Pages 141-151
GnRH Receptor Microaggregation: Regulation of Gonadotropin Release, GnRH Receptors, and Gonadotrope Responsiveness....Pages 153-167
Recent Progress in Cell Biology of Secretory Process in Anterior Pituitary Cells....Pages 169-180
Fluidity of Gonadotropin Storage in Cycling Female Rats....Pages 181-198
Regulation of Peptide Hormone Receptors in the Pituitary-Gonadal Axis: Receptors to Gonadotropins and Gonadotropin Releasing Hormone....Pages 199-218
Strategies for the Inhibition of Gonadotropin Action....Pages 219-234
The Role of Carbohydrate Moiety of Gonadotropin Molecule in Transduction of Biological Signal....Pages 235-248
Intraovarian Regulation of Follicular Granulosa Cell Differentiation....Pages 249-261
Calcium: A Cellular Mediator of Luteolysis....Pages 263-272
New Perspectives on the Endocrine Regulation of the Rabbit Corpus Luteum....Pages 273-288
Secretion and Action of Steroids in the Luteal Cell....Pages 289-307
Hormones in Antral Fluid and the Regulation of Ovarian Function....Pages 309-324
Regulation of Oocyte Maturation....Pages 325-336
Mechanisms Involved in Follicular Rupture in the Rat....Pages 337-353
The Role of Cell-Cell Communication in Neuropeptide-Stimulated and Dopamine-Inhibited Prolactin Release....Pages 355-366
Modulation of Prolactin Secretion at the Pituitary Level: Involvement of Adenylate Cyclase....Pages 367-383
Hormonal Regulation of Casein Gene Expression in Normal and Transformed Mammary Cells....Pages 385-396
In Vivo Regulation by Estradiol of the Messenger RNAs Encoding LH and FSH Subunits and the Secretion of Gonadotropins....Pages 397-409
Follicle Stimulating Hormone Regulation of Phosphodiesterase and Cell Response....Pages 411-422
Regulation of Steroidogenic Activities in Leydig Cells by LH and an LHRH Agonist....Pages 423-436
Molecular Heterogeneity of Luteinizing Hormone-Releasing Hormone....Pages 437-453
The Biological Actions of ‘Testicular LHRH’....Pages 455-465
Luteinizing Hormone-Releasing Hormone Independently Stimulates Cytodifferentiation of Granulosa Cells....Pages 467-478
Action of LHRH Analogues on Rat Leydig Cells in Vitro : Effects on Cyclic AMP, Ca 2+ , Cholesterol Side Chain Cleavage and Cell Size....Pages 479-492
Phospholipid Turnover in Gonadotropin-Releasing Hormone Target Cells: Comparative Studies....Pages 493-508
Relation of Endogenous Opiates to Secretion of Gonadotropins....Pages 509-519
Structure — Function of LH-RH Analogs and Design Applications to other Peptide Systems....Pages 521-529
Medical Castration with LHRH Agonists and the Need for Combined Treatment with an Antiandrogen in Prostate Cancer....Pages 531-549
Potential Use of LHRH and Analogues: Clinical Implications....Pages 551-562
Application of GnRH for Induction of Ovulation in Anovulatory Menstruating Women....Pages 563-576
Pulsatile Administration of Gn-RH in Hypothalamic Amenorrhea....Pages 577-592
On the Mode of Action of an LHRH Agonist in Man and Its Potential Use as Contraceptive....Pages 593-601
Hypothalamic-Pituitary-Gonadal Axis: Concluding Remarks....Pages 603-610
Back Matter....Pages 611-622