High Density Lipoproteins, Dyslipidemia, and Coronary Heart Disease

Front Matter....Pages i-xi
Introduction to High-Density Lipoprotein, Dyslipidemia, and Coronary Heart Disease....Pages 1-14
Regulation of ApoA-I Gene Expression and Prospects to Increase Plasma ApoA-I and HDL Levels....Pages 15-24
High Density Lipoprotein Particles....Pages 25-32
The Kinetics and Remodeling of HDL Particles: Lessons from Inborn Errors of Lipid Metabolism....Pages 33-44
HDL Structure, Function, and Antiinflammatory Properties....Pages 45-53
Human Apolipoprotein A-I Deficiency....Pages 55-61
Human Apolipoprotein A-I Mutants....Pages 63-69
ATP Binding Cassette A1 Transporter Function and Tangier Disease....Pages 71-77
The Role ABCG1 in Cellular Cholesterol Efflux: Relevance to Atherosclerosis and Endothelial Function....Pages 79-82
In Vitro Studies and Mass Flux of Cholesterol Between Serum and Macrophages....Pages 83-88
Genetic LCAT Deficiency: Molecular Diagnosis, Plasma Lipids, and Atherosclerosis....Pages 89-93
Human Cholesteryl Ester Transfer Protein in Human HDL Metabolism....Pages 95-101
The HDL Receptor SR-BI....Pages 103-109
Genetic Loci Influencing Plasma High Density Lipoprotein Cholesterol Concentrations in Humans....Pages 111-120
Nutritional and Lifestyle Factors and High-Density Lipoprotein Metabolism....Pages 121-127
Effects of Ethanol Intake on High Density Lipoprotein Metabolism in Humans....Pages 129-138
Effects of Estrogen on HDL Metabolism....Pages 139-143
Effects of Niacin on HDL Metabolism....Pages 145-149
Effects of Statins on HDL Metabolism....Pages 151-155
Therapeutic Regulation of High-Density Lipoprotein Transport in the Metabolic Syndrome....Pages 157-163
Effects of Cholesterol Ester Transfer Protein Inhibition on HDL Metabolism....Pages 165-171
HDL Infusion Therapy....Pages 173-179
High Density Lipoproteins, Dyslipidemia, and Heart Disease: Past, Present, and Future....Pages 181-199
Back Matter....Pages 201-205