Hemoglobins, Part C Biophysical Methods

Contributors to Volume 232......Page 2
Preface......Page 5
Volume In Series......Page 7
[1] Acid-induced folding of heme proteins......Page 21
[2] X-ray crystallography of partially liganded structures......Page 34
[3] Structure and energy change in hemoglobin by hydrogen exchange labeling......Page 46
[4] High-pressure fluorescence methods for observing subunit dissociation in hemoglobin......Page 63
[5] Optical measurements of quaternary structural changes in hemoglobin......Page 77
[6] Allosteric equilibrium measurements with hemoglobin valency hybrids......Page 93
[7] Electron-transfer reactions of hemoglobin with small molecules A potential probe of conformational dynamics......Page 109
[8] Proton nuclear magnetic resonance studies of hemoglobin......Page 118
[9] Infrared methods for study of hemoglobin reactions and structures......Page 161
[10] Picosecond infrared spectroscopy of hemoglobin and myoglobin......Page 198
[11] Time-resolved resonance raman spectroscopy as probe of structure, dynamics, and reactivity in hemoglobin......Page 227
[12] Front-face fluorescence spectroscopy of hemoglobins......Page 254
[13] Stationary and time-resolved circular dichroism of hemoglobins......Page 270
[14] X-ray absorption spectroscopy of hemoglobin......Page 290
[15] Modulated excitation spectroscopy in hemoglobin......Page 317
[16] Picosecond phase grating spectroscopy applications to bioenergetics and protein dynamics......Page 347
[17] Assignment of rate constants for O2 and CO binding to α and β subunits within R- and T-state human hemoglobin......Page 386
[18] Ligand binding and conformational changes measured by time-resolved absorption spectroscopy......Page 410
[19] Femtosecond measurements of geminate recombination in heme proteins......Page 439
[20] Double mixing methods for kinetic studies of ligand binding in partially liganded intermediates of hemoglobin......Page 454
[21] Hemoglobin-liganded intermediates......Page 470
[22] Hemoglobin-oxygen equilibrium binding Rapid-scanning spectrophotometry and singular value decomposition......Page 486
[23] Oxygen equilibrium curve of concentrated hemoglobin......Page 512
[24] Bezafibrate derivatives as potent effectors of hemoglobin......Page 522
[25] Simulation of hemoglobin kinetics using finite element numerical methods......Page 540
[26] Adair fitting to oxygen equilibrium curves of hemoglobin......Page 582
[27] Weighted nonlinear regression analysis of highly cooperative oxygen equilibrium curves......Page 600
[28] Dimer-tetramer equilibrium in Adair fitting......Page 622
[29] Effects of wavelength on fitting Adair constants for binding of oxygen to human hemoglobin......Page 632
[30] Adair equation Rederiving oxygenation parameters......Page 659
[31] Linkage thermodynamics......Page 683
Author Index......Page 712
Subject Index......Page 735