Heme Oxygenase in Biology and Medicine

Front Matter....Pages i-xix
Front Matter....Pages 1-1
Development of Heme Oxygenase Inhibitors for the Prevention of Severe Jaundice in Infants....Pages 3-17
Carbon Monoxide....Pages 19-29
Correlation of the Altered Vascular Effects of Carbon Monoxide and the Cardiovascular Complications of Diabetes....Pages 31-41
Endogenous Carbon Monoxide has Protective Roles in Neointimal Development Elicited by Arterial Injury....Pages 43-54
End Tidal Breath Carbon Monoxide (ETCO) Levels in Pregnant Women....Pages 55-65
The Role of Heme Oxygenase in Pregnancy....Pages 67-82
Increased Carbon Monoxide in Exhaled Air in Patients with Inflammatory Respiratory Diseases....Pages 83-95
Carbon Monoxide and Iron, by-Products of Heme Oxygenase, Modulate Vascular Endothelial Growth Factor Synthesis in Vascular Smooth Muscle Cells....Pages 97-107
Front Matter....Pages 109-109
Co and Neonatal Cerebral Circulation....Pages 111-119
Differential Expression of Heme Oxygenase-1 in Rat Brain by Endotoxin (LPS)....Pages 121-134
Role of Heme Catabolism in Neurodegenerative Diseases....Pages 135-143
Heme Oxygenase-1 and Alzheimer Disease....Pages 145-155
Early Molecular Mechanisms for the Induction of Neuronal Membrane Asymmetry and Genomic DNA Cleavage....Pages 157-167
Heme Oxygenase (HO)-1 Expressing Macrophages/Microglial Cells Accumulate During Oligodendroglioma Progression....Pages 169-180
Front Matter....Pages 181-181
Heme Oxygenase and Ocular Surface Inflammation....Pages 183-192
Targeted Expression of Heme Oxygenase-1 and Pulmonary Responses to Hypoxia....Pages 193-204
Heme Oxygenase in Skeletal Muscle....Pages 205-213
Heme Oxygenase-1 (HO-1)....Pages 215-226
Thioredoxin Facilitates the Induction of Heme Oxygenase-1 in Response to Inflammatory Mediators....Pages 227-237
Front Matter....Pages 239-239
Induction of Heme Oxygenase-1 as a Protective Response Against Heme Protein-Induced Renal Injury....Pages 241-250
Front Matter....Pages 239-239
Regulation and Role of Heme Oxygenase-1 in Glomerulonephritis....Pages 251-258
Heme Oxygenase-1 Mediates Atrial Natriuretic Peptide Induced Protection of Renal Cells from Cyclosporin Toxicity....Pages 259-268
Heme Oxygenase and Atherosclerosis....Pages 269-278
Atherogenicity of Hypercholesterolemia in the Precense of Hemolysis in Spite of Heme Oxygenase-1 Induction....Pages 279-292
Anti-Atherogenic Properties of Heme Oxygenase....Pages 293-301
Heme Oxygenase and the Novel Tumour-Specific Anti-Vascular Compound Combretastatin A4-Phosphate....Pages 303-312
The Heme Oxygenase/Carbon Monoxide System in Hepatobiliary Pathophysiology....Pages 313-322
Front Matter....Pages 323-323
Human Heme Oxygenase (HO)-1 Deficiency and the Oxidative Injury of Vascular Endothelial Cells....Pages 325-334
Heme Oxygenase Induction in Liver Cells by Hepatocyte Growth Factor and Oxidative Stress....Pages 335-341
Response of Heme Oxygenase and Telomerase Enzymes to Oxidative Stress in Human Hepatoma Cell Line (HepG2)....Pages 343-351
The Influence of Glucuronidation on in Vitro Assessment of Bilirubin Production as Measure of HO Activity....Pages 353-363
Molecular Mechanism of Heme Oxygenase-1 Gene Induction by Activation of the Protein Kinase A-Dependent Signaling Pathway....Pages 365-375
Regulation of Heme Oxygenase-1 Gene Transcription Via the Stress-Response Element....Pages 377-386
Heme Oxygenase-1....Pages 387-397
Heme Oxygenase, Ginkgo Biloba Extract and its Terpenoids Protect Myocytes Against Oxidative Injury....Pages 399-408
Tobacco-Smoke-Inducible Human Heme Oxygenase-1 Gene Expression....Pages 409-421
Doppel Protein Expression Correlates with Heme Oxygenase 1 and Nitric Oxide Synthase Induction....Pages 423-430
Generation of Nitric Oxide and Carbon Monoxide Provide Protection Against Cardiac Anaphylaxis....Pages 431-435
Front Matter....Pages 437-437
Heme Oxygenase-1 Inhibits Vascular Smooth Muscle Cell Proliferation....Pages 439-447
Induction of Apoptosis in Vascular Smooth Muscle Cells by Heme Oxygenase-1-Derived Carbon Monoxide....Pages 449-457
Front Matter....Pages 437-437
Role of Heme Oxygenase in Angiogenesis and Renal Carcinoma....Pages 459-467
On the Promoting Action of Tamoxifen in the P-Dimethylaminoazobenzene Induced Hepatocarcinogenesis CF1 Mice Model and the Cytoprotective Role of Heme Oxygenase....Pages 469-479
Human Heme Oxygenase Gene Transfer Promotes Body Growth and Normalizes Blood Pressure in Spontaneously Hypertensive Rats Without Affecting Sprague-Dawley Rats....Pages 481-494
Back Matter....Pages 495-515